EA-2192

EA-2192
Names
Preferred IUPAC name
S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate
Other names
Diisopropylaminoethyl methyl thiolophosphonate
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • CC(C)N(CCSP(=O)(C)O)C(C)C
Properties
C9H22NO2PS
Molar mass 239.31 g·mol−1
Appearance White solid
Very soluble
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely toxic
Lethal dose or concentration (LD, LC):
630 μg/kg (Rat, oral)
18 μg/kg (Rat, iv)
50 μg/kg (Mouse, iv)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

EA-2192 is an extremely toxic degradation product of the VX nerve agent.[1][2] It is a white solid that is very soluble and stable in water.

EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself.[3]

EA-2192 behaves similar to aged Soman as it is the dealkylated form of VX and cannot be reversed with common oxime reactivators.

EA-2192 from VX

See also

References

  1. ^ Ellison, D. Hank (2007). Handbook of chemical and biological warfare agents (2nd ed.). Boca Raton, Fla.: CRC. ISBN 9780849314346.
  2. ^ Hoenig, Steven L. (2007), Compendium of Chemical Warfare Agents, Springer, ISBN 978-0-387-34626-7
  3. ^ Munro, NB; Talmage, SS; Griffin, GD; Waters, LC; Watson, AP; King, JF; Hauschild, V (December 1999). "The sources, fate, and toxicity of chemical warfare agent degradation products". Environmental Health Perspectives. 107 (12): 933–74. doi:10.1289/ehp.99107933. PMC 1566810. PMID 10585900.
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