Clomocycline

Clomocycline
Skeletal formula of clomocycline
Ball-and-stick model of the clomocycline molecule
Clinical data
Other names(2Z,4S,4aS,5aS,6S,12aS)-7-chloro-4-dimethylamino-6,10,11,12a-tetrahydroxy-2-[hydroxy-(hydroxymethylamino)methylidene]-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione
ATC code
Identifiers
  • (4S,4aS,5aS,6S,12aR)-7-Chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-N-(hydroxymethyl)-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H25ClN2O9
Molar mass508.91 g·mol−1
3D model (JSmol)
  • Clc1c4c(c(O)cc1)C(\O)=C3\C(=O)[C@]2(O)C(=O)/C(C(=O)[C@@H](N(C)C)[C@@H]2C[C@@H]3[C@@]4(O)C)=C(\O)NCO
  • InChI=1S/C23H25ClN2O9/c1-22(34)8-6-9-16(26(2)3)18(30)14(21(33)25-7-27)20(32)23(9,35)19(31)12(8)17(29)13-11(28)5-4-10(24)15(13)22/h4-5,8-9,16,27-28,30-31,34-35H,6-7H2,1-3H3,(H,25,33)/t8?,9-,16-,22-,23-/m0/s1 checkY
  • Key:GJGDLRSSCNAKGL-BJNNJSPUSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Clomocycline is a tetracycline antibiotic. It is used to treat Pustulosis palmaris et plantaris.[1]

References

  1. ^ Ward JM, Corbett MF, Hanna MJ (September 1976). "A double-blind trial of clomocycline in the treatment of persistent palmoplantar pustulosis". The British Journal of Dermatology. 95 (3): 317–322. doi:10.1111/j.1365-2133.1976.tb07020.x. PMID 788767. S2CID 38040660.
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