The 2022 Málaga Open was a professional tennis tournament played on hard courts. It was the first edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Málaga, Spain between 27 June and 3 July 2022.
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
