Annonacina
| Annonacina | |
|---|---|
 | |
| Caratteristiche generali | |
| Formula bruta o molecolare | C35H64O7 |
| Massa molecolare (u) | 596,88 |
| Numero CAS | |
| PubChem | 354398 |
| SMILES | CCCCCCCCCCCCC(C1CCC(O1)C(CCCCC(CCCCCC(CC2=CC(OC2=O)C)O)O)O)O |
| Indicazioni di sicurezza | |
L'annonacina è una sostanza organica naturale appartenente alla classe delle acetogenine, isolata da piante appartenenti alla famiglia delle annonaceae.
Bibliografia
- (EN) A Lannuzel, et al., The mitochondrial complex i inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism, in Neuroscience, vol. 121, n. 2, International Brain Research Organization, 6 ottobre 2003, pp. 287–296, DOI:10.1016/S0306-4522(03)00441-X, PMID =14521988. URL consultato il 13 dicembre 2006.
- (EN) Champy, Pierre; Hoeglinger, Guenter U.; Feger, Jean; Gleye, Christophe; Hocquemiller, Reynald; Laurens, Alain; Guerineau, Vincent; Laprevote, Olivier; Medja, Fadia; Lombes, Anne; Michel, Patrick P.; Lannuzel, Annie; Hirsch, Etienne C.; Ruberg, Merle, Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: Possible relevance for atypical parkinsonism in Guadeloupe, in Journal of Neurochemistry, vol. 88, n. 1, 2004, pp. 63–69, DOI:10.1046/j.1471-4159.2003.02138.x, PMID 14675150.
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