In enzymology, a succinyl-CoA:(R)-benzylsuccinate CoA-transferase (EC 2.8.3.15) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + (R)-2-benzylsuccinate ${\displaystyle \rightleftharpoons }$ succinate + (R)-2-benzylsuccinyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and (R)-2-benzylsuccinate, whereas its two products are succinate and (R)-2-benzylsuccinyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase. This enzyme is also called benzylsuccinate CoA-transferase. This enzyme participates in benzoate degradation via coa ligation.

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• Leuthner B, Heider J (2000). "Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate". J. Bacteriol. 182 (2): 272–7. doi:10.1128/JB.182.2.272-277.2000. PMC 94273. PMID 10629170.
• Heider J (2001). "A new family of CoA-transferases". FEBS Lett. 509 (3): 345–9. doi:10.1016/S0014-5793(01)03178-7. PMID 11749953.