Mitochondrially encoded tRNA asparagine also known as MT-TN is a transfer RNA which in humans is encoded by the mitochondrial MT-TN gene.[1]
The MT-TN gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 73 base pairs.[2] The structure of a tRNA molecule is a distinctive folded structure which contains three hairpin loops and resembles a three-leafed clover.[3]
MT-TN is a small 73 nucleotide RNA (human mitochondrial map position 5657-5729) that transfers the amino acid asparagine to a growing polypeptide chain at the ribosome site of protein synthesis during translation.
Mutations in MT-TN have been associated with isolated ophthalmoplegia. Ophthalmoplegia is a condition characterized by eye muscle weakness. Common symptoms of the disorder include hearing loss, loss of sensation in the limbs, ataxia, and neuropathy.[4] Multiple mutations of 5692A>G and 5703G>A have been found in patients with ophthalmoplegia.[5][6][7] Such mutations in MT-TN resulted in a failure in oxidative phosphorylation and protein synthesis of the mitochondria. In addition, a 5728A>G transition of MT-TN was found to result in a combined deficiency of complex I and IV, with symptoms of failure to thrive, renal failure, and mental retardation.[8]
MT-TN mutations have been associated with complex IV deficiency of the mitochondrial respiratory chain, also known as the cytochrome c oxidase deficiency. Cytochrome c oxidase deficiency is a rare genetic condition that can affect multiple parts of the body, including skeletal muscles, the heart, the brain, or the liver. Common clinical manifestations include myopathy, hypotonia, and encephalomyopathy, lactic acidosis, and hypertrophic cardiomyopathy.[9] 5709T>C[10][11] mutations in MT-TN have been found in patients with the deficiency.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
American fitness company SoulCycleFront entrance to a Manhattan SoulCycle studio.TypeSubsidiaryIndustryPhysical fitnessFounded2006; 17 years ago (2006)FoundersElizabeth CutlerJulie RiceRuth ZukermanHeadquartersNew York CityNumber of locations99 (2020)[1]U.S. Locations: 60 (2023)Key peopleEvelyn Webster, CEOProductsExercise equipmentServicesIndoor cycling and Spinning classesNumber of employees1,500 (2016)ParentEquinox GroupWebsitesoul-cycle.com Ruth Zukerman in July 201…
This article uses bare URLs, which are uninformative and vulnerable to link rot. Please consider converting them to full citations to ensure the article remains verifiable and maintains a consistent citation style. Several templates and tools are available to assist in formatting, such as reFill (documentation) and Citation bot (documentation). (August 2022) (Learn how and when to remove this template message) Hall Green StadiumFull nameHall Green Greyhound StadiumLocationYork Road, Hall Green, …
Este artículo se refiere o está relacionado con un evento de salud pública reciente o actualmente en curso. La información de este artículo puede cambiar frecuentemente. Por favor, no agregues datos especulativos y recuerda colocar referencias a fuentes fiables para dar más detalles. Pandemia de COVID-19 en Colombia Parte de la pandemia de COVID-19 Mapa de departamentos con casos confirmados de coronavirus (SARS-CoV-2)[1][2][3] de 32 departamentos más el Distrito Capi…
Airport in London, EnglandLondon HeliportIATA: noneICAO: EGLWSummaryAirport typePublicOwnerReuben BrothersOperatorThe London Airport Ltd.LocationBattersea, London, EnglandElevation AMSL18 ft / 5 mCoordinates51°28′12″N 000°10′46″W / 51.47000°N 0.17944°W / 51.47000; -0.17944Websitewww.londonheliport.co.uk MapEGLWLocation in Greater LondonRunways Direction Length Surface m ft 02/20 38 × 16 125 × 52 Concrete Sources: UK AIP at …
1st century CE High Priest of Israel This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Joseph Cabi ben Simon – news · newspapers · books · scholar · JSTOR (January 2012) (Learn how and when to remove this template message) Joseph Cabi ben Simon was a Herodian-era High Priest of Israel in Jerusalem, Iudaea Provinc…
Blick vom Nosal Blick vom Nosal Gutshof und Park Parkanlage Untere Seilbahnstation 1939 Die Kuźnice ist ein Stadtteil der polnischen Stadt Zakopane in der Westtatra im Powiat Tatrzański in der Woiwodschaft Kleinpolen. Inhaltsverzeichnis 1 Lage 2 Geschichte 3 Etymologie 4 Verkehr 5 Tourismus 6 Weblinks 7 Belege 8 Panorama Lage Der Stadtteil liegt im Süden der Stadt auf einer Höhe von 1011 Metern über NN innerhalb des Tatra-Nationalparks im Tal Dolina Bystrej. Um den Ortsteil erheben sich die…
جبل تيان آن من الموقع الصين المنطقة زانغجياجي إحداثيات 29°03′10″N 110°28′59″E / 29.0528°N 110.483°E / 29.0528; 110.483 الارتفاع 1519 متر النتوء 1518.6 متر تعديل مصدري - تعديل جبل تيان آن من (الصينية: 天門山 ؛ بينيين: Tiānmén Shān) هو جبل يقع داخل حديقة جبل تيان آن من الوطنية في…
Truida Heil-Bonnet Na de Steenwedstrijd mocht Truida Heil-Bonnet in de Turnhal Amsterdam een beker in ontvangst nemen (24 december 1947) Persoonlijke informatie Volledige naam Geertruida Johanna Heil-Bonnet Bijnaam Truida Geboortedatum 11 juli 1920 Geboorteplaats Amsterdam Overlijdensdatum 4 juli 2014 Overlijdensplaats Varsseveld Nationaliteit Nederland Sportieve informatie Discipline gymnastiek Club DOC Amsterdam (Dol Olympia Combinatie) Varsseveldse Gymnastiek Vereniging Olympische Spele…
Ґуставо Маркассіо Gustavo Marcaccio Громадянство АргентинаМісце проживання Буенос-Айрес, АргентинаДата народження 3 травня 1977Місце народження Буенос-Айрес, АргентинаЗріст 170 смРобоча рука праваБекхенд одноручнийПризові, USD $131,434Одиночний розрядМатчів в/п 2–3 (на турнірах Т…
ガリレオシリーズ > ガリレオ (テレビドラマ) ガリレオ 湯川学の研究室の再現セット(FCGビル内)ジャンル テレビドラマ、ミステリー原作 東野圭吾『ガリレオシリーズ』(文藝春秋)第1シーズン 『探偵ガリレオ』『予知夢』ガリレオΦ『ガリレオの苦悩』第2シーズン 『ガリレオの苦悩』『聖女の救済』『虚像の道化師 ガリレオ7』『禁断の魔術 ガリレオ8』脚本 第…
Natalia Almada Natalia Almada adalah seorang pembuat film dokumenter keturunan Meksiko-Amerika Serikat. Film dokumenter yang dibuatnya selalu mengungkapkan permasalahan lintas budaya.[1] Natalia Almada lahir di Kota Meksiko City pada tahun 1974.[2] Almada telah merilis beberapa film, yaitu To the Other Side (2005), El General (2009), dan El Velador (2012).[1] Film-film Almada telah diputar di Documenta, Museum Seni Modern, Museum Guggenheim dan The Whitney Biennial.[3…
Agnee 2Theatrical Release PosterSutradara Iftakar Chowdhury Produser Jaaz Multimedia Ditulis olehPemeran Om Mahiya Mahi Ashish Vidyarthi Amit Hasan Penata musikSavvyAkaashPerusahaanproduksiJaaz MultimediaDistributorJaaz Multimedia (Worldwide)Eskay Movies(India)Tanggal rilis 18 Juli 2015 (2015-07-18) Negara Bangladesh Bahasa Bengal Agnee 2 adalah film Bangladesh-India produksi tahun 2015 bergenre aksi yang disutradarai oleh Iftakar Chowdhury. Film ini merupakan sequel lanjutan dari fil…
تحتاج النصوص المترجمة في هذه المقالة إلى مراجعة لضمان معلوماتها وإسنادها وأسلوبها ومصطلحاتها ووضوحها للقارئ، لأنها تشمل ترجمة اقتراضية أو غير سليمة. فضلاً ساهم في تطوير هذه المقالة بمراجعة النصوص وإعادة صياغتها بما يتناسب مع دليل الأسلوب في ويكيبيديا.هذه المقالة يتيمة إذ …
1965 studio album by Roy OrbisonOrbisongsStudio album by Roy OrbisonReleasedNovember 1965RecordedSeptember 15, 1960 - June 1, 1965GenreRockLength30:34LabelMonumentProducerFred FosterRoy Orbison chronology There Is Only One Roy Orbison(1965) Orbisongs(1965) The Orbison Way(1966) Orbisongs is a compilation LP released by Monument Records in 1965 after Roy Orbison had left the label and joined MGM. It features tracks such as the stereo version of Oh, Pretty Woman, a different version of Dan…
Fictional British school of magic from the Harry Potter universe Not to be confused with Hogwort. This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Hogwarts – news · newspapers…
2 Raja-raja 9Kitab Raja-raja (Kitab 1 & 2 Raja-raja) lengkap pada Kodeks Leningrad, dibuat tahun 1008.KitabKitab 2 Raja-rajaKategoriNevi'imBagian Alkitab KristenPerjanjian LamaUrutan dalamKitab Kristen12← pasal 8 pasal 10 → 2 Raja-raja 9 (atau II Raja-raja 9, disingkat 2Raj 9) adalah pasal kesembilan Kitab 2 Raja-raja dalam Alkitab Ibrani dan Perjanjian Lama di Alkitab Kristen. Dalam Alkitab Ibrani termasuk Nabi-nabi Awal atau Nevi'im Rishonim [נביאים ראשונים] dalam …
East German discus thrower You can help expand this article with text translated from the corresponding article in German. (March 2022) Click [show] for important translation instructions. View a machine-translated version of the German article. Machine translation, like DeepL or Google Translate, is a useful starting point for translations, but translators must revise errors as necessary and confirm that the translation is accurate, rather than simply copy-pasting machine-translated text i…
Fakultas Ekonomi dan Bisnis Universitas Jenderal SoedirmanFEB UnsoedLambang Universitas Jenderal SoedirmanNama sebelumnyaFakultas Ekonomi Universitas Jenderal SoedirmanDidirikan1963Lembaga indukUniversitas Jenderal SoedirmanAfiliasiABEST21, LAMEMBA DekanProf. Wiwiek Rabiatul Adawiyah, B.Acc, M.Sc, Ph.D (2021-sekarang)AlamatFakultas Ekonomi dan BisnisJl. Prof. Dr. HR Boenyamin No. 708, Kampus Grendeng Unsoed, Purwokerto, Jawa Tengah, Indonesia KampusUrbanWarna KelabuSitus webhttp://www.feb.…
American pornographic actress and model (born 1970) Stacy ValentineValentine at a Penthouse talent call in Woodland Hills, Los Angeles, December 2004BornStacy Baker (1970-08-09) August 9, 1970 (age 53)Tulsa, Oklahoma, U.S.Other namesStacy, Stacey, Stacey Valentin, Staci Valentine, Stacey ValentineHeight5 ft 4 in (1.63 m)Websitewww.stacyvalentine.com Stacy Valentine (born Stacy Baker on August 9, 1970) is an American former pornographic actress. She is a member of both th…
South Korean comedian and actress (born 1989) For the actress of the same name, see Lee Se-young. In this Korean name, the family name is Lee. Lee Se-YoungBorn (1989-04-28) April 28, 1989 (age 34)Incheon, South KoreaMediumStand-upTelevision comedyNationalitySouth KoreanYears active2011-presentGenresObservationalSketchWitParodySlapstickDramaticSitcom Korean nameHangul이세영Revised RomanizationI Se-yeongMcCune–ReischauerI Se-yŏng Lee Se-Young (born April 28, 1989) is a South Korean come…
Lokasi Pengunjung: 18.117.9.85