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COPG1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1R4X
Identifiers
Aliases	COPG1, COPG, coatomer protein complex subunit gamma 1, COPI coat complex subunit gamma 1
External IDs	OMIM: 615525; MGI: 1858696; HomoloGene: 56745; GeneCards: COPG1; OMA:COPG1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	129,277,773 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	87,890,577 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; anterior pituitary; ; body of pancreas; ; mucosa of transverse colon; ; islet of Langerhans; ; minor salivary glands; ; right lobe of thyroid gland; ; body of stomach; ; right adrenal gland; ; rectum;
	Top expressed in
	yolk sac; ; dentate gyrus of hippocampal formation granule cell; ; molar; ; superior frontal gyrus; ; supraoptic nucleus; ; Pituitary Gland; ; dermis; ; central gray substance of midbrain; ; islet of Langerhans; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; structural molecule activity;
Cellular component	cytoplasm; membrane coat; COPI-coated vesicle membrane; membrane; transport vesicle; cytosol; cytoplasmic vesicle; Golgi apparatus; Golgi membrane; COPI vesicle coat; endoplasmic reticulum membrane; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment;
Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; protein transport; organelle transport along microtubule; intracellular protein transport; establishment of Golgi localization; endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle-mediated transport; intra-Golgi vesicle-mediated transport; protein secretion;
	Sources:Amigo / QuickGO
Orthologs
	22820
	54161
	ENSG00000181789
	ENSMUSG00000030058
	Q9Y678
	Q9QZE5
	NM_016128
	NM_017477; NM_201244
	NP_057212
	NP_059505; NP_957696
	Wikidata
View/Edit Human	View/Edit Mouse

Coatomer subunit gamma is a protein that in humans is encoded by the COPG gene.^[5]^[6] It is one of seven proteins in the COPI coatomer complex that coats vesicles as they bud from the Golgi complex.^[5]

Interactions

COPG has been shown to interact with Dopamine receptor D1,^[7] COPZ1^[5]^[8] and COPB1.^[5]^[9]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000181789 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030058 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b ^c ^d Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (February 2001). "Identification and characterization of novel isoforms of COP I subunits". J Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.
^ "Entrez Gene: COPG coatomer protein complex, subunit gamma".
^ Bermak, Jason C; Li Ming; Bullock Clayton; Weingarten Paul; Zhou Qun-Yong (February 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. 81 (2). Germany: 77–85. doi:10.1078/0171-9335-00222. ISSN 0171-9335. PMID 11893085.
^ Faulstich, D; Auerbach S; Orci L; Ravazzola M; Wegchingel S; Lottspeich F; Stenbeck G; Harter C; Wieland F T; Tschochner H (October 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell Biol. 135 (1). UNITED STATES: 53–61. doi:10.1083/jcb.135.1.53. ISSN 0021-9525. PMC 2121028. PMID 8858162.
^ Lowe, M; Kreis T E (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48). UNITED STATES: 30725–30. doi:10.1074/jbc.271.48.30725. ISSN 0021-9258. PMID 8940050.