1IU1
164
11765
ENSG00000166747
ENSMUSG00000031731
O43747
P22892
NM_001128NM_001030007
NM_001301211NM_009677
NP_001025178NP_001119
NP_001288140NP_033807
AP-1 complex subunit gamma-1 is a protein that in humans is encoded by the AP1G1 gene.[5][6]
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.[7]
AP1G1 has been shown to interact with:
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