AP2A2

AP2A2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAP2A2, ADTAB, CLAPA2, HIP-9, HIP9, HYPJ, adaptor related protein complex 2 alpha 2 subunit, adaptor related protein complex 2 subunit alpha 2
External IDsOMIM: 607242; MGI: 101920; HomoloGene: 5335; GeneCards: AP2A2; OMA:AP2A2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

161

11772

Ensembl

ENSG00000281385
ENSG00000280759
ENSG00000183020

ENSMUSG00000002957

UniProt

O94973

P17427

RefSeq (mRNA)

NM_001242837
NM_012305

NM_007459
NM_001357068

RefSeq (protein)

NP_001229766
NP_036437

NP_031485
NP_001343997

Location (UCSC)Chr 11: 0.92 – 1.01 MbChr 7: 141.14 – 141.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.[5][6][7]

Interactions

AP2A2 has been shown to interact with EPN1[8] and SHC1.[9]

References

  1. ^ a b c ENSG00000280759, ENSG00000183020 GRCh38: Ensembl release 89: ENSG00000281385, ENSG00000280759, ENSG00000183020 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002957 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202.
  6. ^ Robinson MS (Mar 1989). "Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins)". The Journal of Cell Biology. 108 (3): 833–42. doi:10.1083/jcb.108.3.833. PMC 2115374. PMID 2564002.
  7. ^ "Entrez Gene: AP2A2 adaptor-related protein complex 2, alpha 2 subunit".
  8. ^ Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (Aug 1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis". Nature. 394 (6695): 793–7. Bibcode:1998Natur.394..793C. doi:10.1038/29555. PMID 9723620. S2CID 4430975.
  9. ^ Okabayashi Y, Sugimoto Y, Totty NF, Hsuan J, Kido Y, Sakaguchi K, Gout I, Waterfield MD, Kasuga M (Mar 1996). "Interaction of Shc with adaptor protein adaptins". The Journal of Biological Chemistry. 271 (9): 5265–9. doi:10.1074/jbc.271.9.5265. PMID 8617812.

Further reading


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