Ramulamma is born into the Dalit caste, making her an "untouchable", in the village. At the age of 13, she is impregnated by the Dora, Jagannayak Patwari. After giving birth to the baby, Patwari learns of its existence. He orders his men to throw the baby away and kill Ramulamma. The baby is found by Naxalites and raised by them. Injured, Ramulamma is taken care of, by a Dalit couple, who treat her as their sister. They live in a typical feudal village in Telangana, where the Doralu (feudal lords), exploit peasants in the name of bonded labour and debts. Ramulamma is asked to work at the palace of the Dora, as a maid for the Dorasani, the wife of the Dora.
One day, Patwari's son attempts to rape Ramulamma. She kills him in his bed. Learning of this, Patwari tries to kill Ramulamma, but she is rescued by Komaranna, a naxalite leader, and is taken to the forest, where Komaranna and the other naxalites live.
She learns their ideology, begins to believe in it, and gradually becomes the leader, after Komaranna steps down. Meanwhile, Ramulamma's son is killed by Patwari. CBI officer, Krishna, who was sent by the Central Government to look into the Naxalite issue, convinces Ramulamma and Komaranna to surrender. But later, he finds that the central government is corrupt and that the Doras are ruling it. He learns that Ramulamma is to be killed by the Dora. He helps Ramulamma escape from jail, but Komaranna and he die in the gunfight with the police. Ramullama finally kills Patwari, in front of the whole village.
The music was composed by Vandemataram Srinivas. Srinivas gained Nandi award and Filmfare south award for his work. The songs (except two) were sung by him.[2]
The film was reviewed by Zamin Ryot.[3] A critic from Andhra Today wrote that "A big hit for the dashing, dare-devil heroine Vijayashanti after a long time is Ose Ramulamma".[4]