Flucindole

Flucindole
Clinical data
Other namesWIN-35150; WIN35150; WIN-35,150
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 6,8-Difluoro-N,N-dimethyl-2,3,4,9-tetrishydro-1H-carbazol-3-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H16F2N2
Molar mass250.293 g·mol−1
3D model (JSmol)
  • CN(C)C1CCC2=C(C1)C3=CC(=CC(=C3N2)F)F
  • InChI=1S/C14H16F2N2/c1-18(2)9-3-4-13-10(7-9)11-5-8(15)6-12(16)14(11)17-13/h5-6,9,17H,3-4,7H2,1-2H3
  • Key:FXNCRITWFOVSEP-UHFFFAOYSA-N
  (verify)

Flucindole (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name; developmental code name WIN-35150) is an antipsychotic with a tricyclic and tryptamine-like structure that was never marketed.[1][2] It is the 6,8-difluoro derivative of ciclindole.[3] The drug is about 5 to 10 times more potent than ciclindole both in vitro and in vivo.[2]

See also

References

  1. ^ Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 556. ISBN 978-1-4757-2085-3. Retrieved 2 November 2024.
  2. ^ a b Wood PL, McQuade PS (1984). "Ciclindole and flucindole: novel tetrahydrocarbazolamine neuroleptics". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 8 (4–6): 773–7. doi:10.1016/0278-5846(84)90057-5. PMID 6152347. S2CID 39252411.
  3. ^ Edelson J, Benziger DP (1980). "Disposition of a series of tetrahydrocarbazoles". Drug Metabolism Reviews. 11 (2): 263–89. doi:10.3109/03602538008994027. PMID 7011760.
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