Spegatrine

Spegatrine
Spegatrine 2D skeletal
Spegatrine 3D BS-model
Identifiers
ChemSpider
  • InChI=1S/C20H24N2O2/c1-3-11-9-22(2)18-8-15-14-6-12(24)4-5-17(14)21-20(15)19(22)7-13(11)16(18)10-23/h3-6,13,16,18-19,21,23H,7-10H2,1-2H3/p+1/b11-3-/t13-,16-,18?,19+,22?/m1/s1
    Key: CC=C1C[N+]2(C3CC1C(C2CC4=C3NC5=C4C=C(C=C5)O)CO)C

    2.1.5Isomeric SMILES

    C/C=C\1/C[N+]2([C@H]3C[C@H]1[C@H](C2CC4=C3NC5=C4C=C(C=C5)O)CO)C
Properties
C20H25N2O2+
Molar mass 325.425 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Spegatrine is an α1- and α2-adrenergic receptor antagonist isolated from Rauvolfia verticillata. Its dimer dispegatrine has greater antagonist affinity for α-adrenergic receptors.[1]

See also

References

  1. ^ "COMPARISON OF THE EFFECTS OF SPEGATRINE AND DISPEGATRINE ON α-ADRENOCEPTORS--《Acta Pharmaceutica Sinica》1986年01期". en.cnki.com.cn. Retrieved 2020-09-16.


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