Angiotensină

Angiotensina este un hormon peptidic care determină vasoconstricție, și, ulterior, creșterea tensiunii arteriale. Acesta este parte a sistemului renină-angiotensină. Angiotensina stimulează eliberarea de aldosteron, hormon corticosuprarenal. Aldosteronul determină retenția de sodiu, care la fel duce la creșterea tensiunii arteriale.

Efecte

Cardiovasculare

Ele sunt vasoconstrictoare puternice directe prin cresterea rezistentei vasculare periferice, având efect atât pe artere, cât și pe vene. Angiotensina II are potențial protrombotic prin adeziunea și agregarea trombocitelor și sinteza de inhibitori ai activatorilor plasminogenului. Stimulează creșterea miocitelor și a celulelor musculare netede, determinând hipertrofie cardiacă.

SNC

Angiotensina II are efect dipsogen (crește senzatia de sete) prin efectele sale asupra organului subfornical al creierului; scade răspunsul reflexului baroreceptor, și stimulează ingestia de sare. Angiotensina crește secreția de ADH în neurohipofiză, precum și secreșia de ACTH din adenohipofiză.

Glande suprarenale

Angiotensina acționează asupra cortexului suprarenal, determinând eliberarea de aldosteron, un hormon implicat în retenția sodiului și secreția potasiului la nivel renal. Concentrația plasmatică crescută a angiotensinei este responsabilă pentru concentrația crescută a aldosteronului prezent în timpul fazei luteale a ciclului menstrual.

Renal

Angiotensina are un efect direct asupra tubilor proximali, prin creșterea reabsorbției de sodiu. Creșterea tensiunii arteriale va menține presiunea de perfuzie renală, însă constricția arteriolelor glomerulare aferente și eferente va tinde să limiteze fluxul sanguin renal. Efectul asupra rezistenței arteriolei eferente este mai mare decât asupra celei a arteriolei aferente, datorită diametrului bazal al acesteia mai mic. Concentrații mari ale angiotensinei pot contracta mezangiul glomerular, reducând suprafața de filtrare glomerulară. Angiotensina II determină eliberarea locală de prostaglandine, care pot declanșa vasodilatație renală.

Read other articles:

PBCom Tower

Office in Makati, PhilippinesPBCom TowerThe building in 2019Record heightTallest in the Philippines from 2000 to 2017[I]Preceded byPetron MegaplazaSurpassed byGrand Hyatt ManilaGeneral informationStatusCompletedTypeOfficeLocation6795 Ayala Avenue corner V.A. Rufino Street, Salcedo Village, Makati, PhilippinesCoordinates14°33′29.90″N 121°1′9.51″E / 14.5583056°N 121.0193083°E / 14.5583056; 121.0193083Construction started1997Opening2000CostUS$74 million[1...

 

Daniel Nguyen

Daniel NguyenKebangsaan Amerika Serikat (2013 - 9/2019)  Vietnam (10/2019 - )Tempat tinggalOxnard, California, Amerika SerikatLahir16 Oktober 1990 (umur 33)Long Beach, California, Amerika SerikatMemulai pro2013KampusUniversitas California SelatanPelatihAmir MarandyTotal hadiah$185,586TunggalRekor (M–K)0–0Gelar0Peringkat tertinggiNo. 189 (13 Juli, 2015)Peringkat saat iniNo. 472 (2 Juli 2018)Hasil terbaik di Grand Slam (tunggal)Australia TerbukaQ1Prancis TerbukaQ1Wimbled...

 

Balto (film)

BaltoSutradaraSimon WellsProduserSteve HicknerSkenarioCliff Ruby Elana Lesser Roger S. H. Schulman David Steven CohenCeritaCliff Ruby Elana LesserPemeran Kevin Bacon Bridget Fonda Jim Cummings Phil Collins Bob Hoskins Penata musikJames HornerSinematograferJan Richter-FriisPenyuntingRenee EdwardsNick FletcherSim Evan-JonesPerusahaanproduksiAmblin EntertainmentAmblimationDistributorUniversal PicturesTanggal rilis 22 Desember 1995 (1995-12-22) Durasi77 menitNegaraAmerika Serikat[1...

Francis Turretin

Francis TurretinFrancis TurretinLahir(1623-10-17)17 Oktober 1623Meninggal28 September 1687(1687-09-28) (umur 63)PekerjaanTeolog Francis Turretin (17 Oktober 1623 – 28 September 1687; juga dikenal sebagai François Turrettini ) adalah seorang teolog skolastik Reformed Jenewa keturunan Italia.[1] Turretin paling dikenal sebagai penentang teologi Calvinis moderat dari Akademi Saumur [2] (yang dipopulerkan oleh Moise Amyraut dan disebut sebagai Amyraldisme ). Ia adalah sal...

 

Padang Ganting, Tanah Datar

Padang GantingKecamatanPemandangan Alam Padang GantingNegara IndonesiaProvinsiSumatera BaratKabupatenTanah DatarPemerintahan • Camat-Populasi • Total- jiwaKode Kemendagri13.04.11 Kode BPS1305070 Luas- km²Nagari/kelurahan- Padang Ganting adalah sebuah kecamatan di Kabupaten Tanah Datar, Sumatera Barat, Indonesia.Berjarak kira-kira 18 km dari Batusangkar (Ibu Kota Kabupaten Tanah Datar) lbsKecamatan Padang Ganting, Kabupaten Tanah Datar, Sumatera BaratNagari A...

 

Eastbourne College

Public school in Eastbourne, East Sussex, England Eastbourne CollegeAddressOld Wish RoadEastbourne, East Sussex, BN21 4JYEnglandCoordinates50°45′46″N 0°16′52″E / 50.7627°N 0.2811°E / 50.7627; 0.2811InformationTypePublic schoolPrivate day and boardingMottoEx oriente salus(The haven [the bourne] from the East)Religious affiliation(s)Church of EnglandEstablished1867FoundersWilliam Cavendish, 7th Duke of Devonshire and other prominent Eastbourne citizensLocal a...

Соколиные горы

Соколиные горы Основная информация Площадь51 га Дата основания1983 Расположение 50°49′00″ с. ш. 27°04′30″ в. д.HGЯO Страна Украина Соколиные горы Медиафайлы на Викискладе Соколиные горы — ландшафтный заказник, расположенный в Ровненском районе Ровненской...

 

Pygostylia

Clade of dinosaurs PygostyliansTemporal range: Early Cretaceous–Present, 136–0 Ma PreꞒ Ꞓ O S D C P T J K Pg N Fossil pygostylian (Confuciusornis sanctus) House sparrow (Passer domesticus) Scientific classification Domain: Eukaryota Kingdom: Animalia Phylum: Chordata Clade: Dinosauria Clade: Saurischia Clade: Theropoda Clade: Avialae Clade: Avebrevicauda Clade: PygostyliaChatterjee, 1997 Subgroups[2] †Confuciusornithidae †Jinguofortisidae[1] Ornithothoraces...

 

2024 New York Republican presidential primary

2024 New York Republican presidential primary ← 2016 April 2, 2024 2028 → ← CTRI →91 Republican National Convention delegates   Candidate Donald Trump Nikki Haley (withdrawn) Home state Florida South Carolina Delegate count 91 0 Popular vote 131,710 20,733 Percentage 82.1% 12.9% County results Congressional district results Trump   60 – 70%   70 – 80%   80 – 90%   >90% Elect...

Saúl Craviotto

Spanish sprinter kayaker Saúl CraviottoCraviotto at the 2013 World ChampionshipsPersonal informationBirth nameSaúl Craviotto RiveroNationalitySpanishBorn (1984-11-03) 3 November 1984 (age 39)Lleida, Catalonia, Spain[1]EducationCatholic University of Murcia[2]Height192 cm (6 ft 4 in)[3]Weight98 kg (216 lb)SportCountrySpainSportSprint kayakEvent(s)K-1 200 m, K-2 200 m, K-2 500 m, K-4 500 mClubClub Deportivo Basico Piragua Madrid[2...

 

Laconi

Laconi LàconiKomuneComune di LaconiLokasi Laconi di Provinsi OristanoNegaraItaliaWilayah SardiniaProvinsiOristano (OR)Pemerintahan • Wali kotaAnna Paola ZacchedduLuas • Total124,75 km2 (48,17 sq mi)Ketinggian555 m (1,821 ft)Populasi (2016) • Total1,878[1]Zona waktuUTC+1 (CET) • Musim panas (DST)UTC+2 (CEST)Kode pos08034Kode area telepon0782Situs webhttp://www.comune.laconi.or.it Laconi (bahasa Sardinia: Là...

 

KM Malta Airlines

Flag carrier of Malta Not to be confused with Malta Air or Air Malta. KM Malta Airlines IATA ICAO Callsign KM KMM SKY KNIGHT Founded2 October 2023; 7 months ago (2023-10-02)(preceded by Air Malta)Commenced operations31 March 2024; 39 days ago (2024-03-31)AOC #MT-80HubsMalta International AirportFleet size7Destinations17Parent companyGovernment of MaltaHeadquartersLuqa, MaltaWebsitewww.kmmaltairlines.com KM Malta Airlines Ltd is the flag carrier of Malt...

Arthur Schopenhauer

German philosopher (1788–1860) Schopenhauer redirects here. For other uses, see Schopenhauer (disambiguation). Arthur SchopenhauerSchopenhauer in 1855Born(1788-02-22)22 February 1788Danzig (Gdańsk), Crown of the Kingdom of Poland, Polish–Lithuanian CommonwealthDied21 September 1860(1860-09-21) (aged 72)Frankfurt, German ConfederationNationalityGermanEducation Illustrious Gymnasium University of Göttingen University of Jena (PhD, 1813) Relatives Johanna Schopenhauer (mother) Adele S...

 

Hazenmore

Village in Saskatchewan, CanadaHazenmoreVillageVillage of HazenmoreHazenmoreShow map of Pinto Creek No. 75HazenmoreShow map of SaskatchewanCoordinates: 49°41′13″N 107°08′17″W / 49.687°N 107.138°W / 49.687; -107.138CountryCanadaProvinceSaskatchewanRural municipalityPinto Creek No. 75Post office Founded1913Government • TypeMunicipal • Governing bodyHazenmore Village Council • MayorTrevor Stender • Administr...

 

Daftar kabupaten dan kota di Papua Pegunungan berdasarkan waktu pembentukan

Lambang Provinsi Papua Pegunungan Peta lokasi Provinsi Papua Pegunungan di Indonesia Artikel utama: Daftar kabupaten di Indonesia menurut waktu pembentukan Berikut adalah artikel mengenai Daftar kabupaten dan/atau kota di Papua Pegunungan berdasarkan waktu pembentukan yang diurutkan berdasarkan abjad. Referensi berdasarkan Undang-Undang Republik Indonesia yang pertama dikeluarkan saat pembentukan kabupaten/kota tersebut meskipun terdapat perundang-undangan terbaru dikemudian hari. No. KodeKe...

Redhead, New South Wales

Suburb of Greater Newcastle, New South Wales, AustraliaRedheadGreater Newcastle, New South WalesRedhead BluffRedheadCoordinates33°00′36″S 151°43′23″E / 33.010°S 151.723°E / -33.010; 151.723Population3,785 (2021 census)[1] • Density701/km2 (1,815/sq mi)Established1829Postcode(s)2290Area5.4 km2 (2.1 sq mi)Location 16 km (10 mi) SSW of Newcastle 6 km (4 mi) SSE of Charlestown LGA(s)City of Lake ...

 

Sabam Sirait

Ini adalah nama Batak Toba, marganya adalah Sirait. Sabam Siraitᯘᯅᯔ᯲ ᯘᯪᯒᯤᯖ᯲ Anggota Dewan Perwakilan Daerahdari DKI JakartaMasa jabatan15 Januari 2018 – 29 September 2021Pengganti Antar Waktu hingga 30 September 2019PendahuluAndi Mappetahang FatwaPenggantiDailami FirdausAnggota Dewan Perwakilan RakyatMasa jabatan1 Oktober 1999 – 30 September 2004Daerah pemilihanDKI JakartaMasa jabatan1 Oktober 1992 – 30 September 1997Daerah pemilihanIrian J...

 

Vincent Laban

Questa voce sugli argomenti calciatori francesi e calciatori ciprioti è solo un abbozzo. Contribuisci a migliorarla secondo le convenzioni di Wikipedia. Segui i suggerimenti dei progetti di riferimento 1, 2. Vincent LabanLaban nel 2010Nazionalità Francia Cipro (dal 2012) Altezza177 cm Peso73 kg Calcio RuoloCentrocampista Squadra Aviron Bayonnais CarrieraSquadre di club1 2003-2005 Nantes 262 (6)2005-2007 Digenīs Morphou42 (8)2007-2013 Anorthōsis119 (16)2...

Stavisky affair

Financial scandal in France Alexandre StaviskyPolice Magazine14 January 1934 The Stavisky affair was a financial scandal in France in 1934, involving embezzler Alexandre Stavisky. The scandal had political ramifications for the Radical-Socialist government after it was revealed that Prime Minister Camille Chautemps had protected Stavisky, who died suddenly in mysterious circumstances. Political rightists engaged in large anti-government demonstrations on 6 February 1934, which resulted in the...

 

Fret

Bar across the neck of stringed instruments For other uses, see Fret (disambiguation). This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Fret – news · newspapers · books · scholar · JSTOR (November 2018) (Learn how and when to remove this message) The neck of a guitar showing the nut (in the background, colour...