Imidazenil

Le informazioni riportate non sono consigli medici e potrebbero non essere accurate. I contenuti hanno solo fine illustrativo e non sostituiscono il parere medico: leggi le avvertenze.
Niente fonti!
Questa voce o sezione sull'argomento farmaci non cita le fonti necessarie o quelle presenti sono insufficienti.
Puoi migliorare questa voce aggiungendo citazioni da fonti attendibili secondo le linee guida sull'uso delle fonti.
Imidazenil
Nome IUPAC
6-(2-Bromophenyl)-8-fluoro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide
Caratteristiche generali
Formula bruta o molecolareC18H12BrFN4O
Massa molecolare (u)399,223 g/mol
Numero CAS151271-08-8
PubChem119194
SMILES
C1C2=C(N=CN2C3=C(C=C(C=C3)F)C(=N1)C4=CC=CC=C4Br)C(=O)N
Dati farmacocinetici
MetabolismoEpatico
Escrezionerenale
Indicazioni di sicurezza
Modifica dati su Wikidata · Manuale

L'imidazenil è uno psicofarmaco appartenente alla categoria delle imidazobenzodiazepine; è un farmaco ansiolitico sperimentale che è strettamente correlato ad altre imidazobenzodiazepine come midazolam, flumazenil e bretazenil.

L'imidazenil è un agonista parziale del recettore delle benzodiazepine (GABA A) molto potente con un profilo di effetti insolito, che produce alcuni degli effetti associati alle normali benzodiazepine come gli effetti anticonvulsivanti e ansiolitici, ma senza alcun effetto sedativo o amnestico. Infatti, l'imidazenil blocca gli effetti sedativi del diazepam, ma senza abbassare la soglia convulsiva, e quindi potenzialmente potrebbe essere un antidoto più flessibile rispetto all'antagonista, il flumazenil, che è solitamente utilizzato per trattare il sovradosaggio di benzodiazepine.

L'imidazenil non è stato ancora sviluppato commercialmente per l'uso nell'uomo, tuttavia è stato suggerito come un trattamento sicuro ed efficace per l'ansia, un anticonvulsivante potente ma non sedativo che potrebbe essere particolarmente utile nel trattamento della schizofrenia.

Voci correlate

Altri progetti

  Portale Chimica

Read other articles:

Aida (film 2015)

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Oktober 2016. AidaSutradaraDriss MriniDitulis olehDriss MriniTanggal rilis 22 Februari 2015 (2015-02-22) Durasi94 menitNegaraMarokoBahasaArab Maroko (Darija)IbraniPrancis Aida (Arab: عايدةcode: ar is deprecated ) adalah sebuah film drama Maroko 2015 yang d...

 

Penghargaan Dadasaheb Phalke

Penghargaan Dadasaheb PhalkeJenisNasionalKategoriSinema IndiaDeskripsiPenghargaan Prestasi Seumur HidupDiinstitusikan1969Penghargaan pertama1969Penghargaan terakhir2015Total yang diberi penghargaan46Dianugerahi olehDirektorat Festival FilmBiaya penghargaan₹1.000.000 (US$14,000)MedaliSwarna Kamal (Teratai Emas)Penerima pertamaDevika RaniPenerima saat iniManoj Kumar Penghargaan Dadasaheb Phalke adalah penghargaan tertinggi dalam bidang sinema di India. Penghargaan tersebut dipe...

 

Academy Awards ke-49

Academy Awards ke-49TanggalSenin, 28 Maret 1977TempatDorothy Chandler Pavilion, Los AngelesPembawa acaraRichard Pryor, Jane Fonda, Ellen Burstyn, Warren BeattyProduserWilliam FriedkinPengarah acaraMarty PasettaSorotanFilm TerbaikRockyPenghargaan terbanyakAll the President's Men dan Network (4)Nominasi terbanyakNetwork dan Rocky (10)Liputan televisiJaringanABCDurasi3 jam, 38 menit ← ke-48 Academy Awards ke-50 → Academy Awards ke-49 diadakan pada 28 Maret 1977, di Dorothy ...

Louis XV

Vous lisez un « bon article » labellisé en 2022. Louis XV Louis XV en costume de sacre, huile sur toile de Louis-Michel van Loo (1762). Titre Roi de France et de Navarre 1er septembre 1715 – 10 mai 1774(58 ans, 8 mois et 9 jours) Couronnement 25 octobre 1722, en la cathédrale de Reims Régent Duc d'Orléans (1715-1723) Premier ministre Cardinal DuboisDuc d'OrléansPrince de CondéCardinal de FleuryDuc de ChoiseulRené-Nicolas de Maupeou Gouvernement M...

 

Battle of Saint-Mihiel

Battle of the First World War Battle of Saint-MihielPart of the Western Front of World War IA Renault FT tank ploughing its way through a trench and starting toward the German line near Saint Michel, France.Date12–15 September 1918LocationSaint-Mihiel salient, France48°53′21″N 05°32′37″E / 48.88917°N 5.54361°E / 48.88917; 5.54361Result Allied victoryBelligerents  United States  France  German Empire Austria-HungaryCommanders and leader...

 

Dover, Massachusetts

Town in Massachusetts, United StatesDover, MassachusettsTownThe Dover Church FlagSealNickname: Town of FriendshipDover is one of the smallest towns in Norfolk county.Coordinates: 42°14′45″N 71°17′00″W / 42.24583°N 71.28333°W / 42.24583; -71.28333Country United StatesState MassachusettsCounty NorfolkSettled1635Incorporated1836Government • TypeOpen town meetingArea • Total39.9 km2 (15.4 sq mi) •...

229762 Gǃkúnǁʼhòmdímà

Trans-Neptunian object 229762 GǃkúnǁʼhòmdímàGǃkúnǁʼhòmdímà and its satellite Gǃòʼé ǃHú, imaged by the Hubble Space Telescope on 2 January 2018Discovery[1][2][3]Discovered byM. E. SchwambM. E. BrownD. L. RabinowitzDiscovery sitePalomar Obs.Discovery date19 October 2007DesignationsMPC designation(229762) GǃkúnǁʼhòmdímàPronunciation English: /ˌɡuːnhoʊmˈdiːmə/ Juǀʼhoan: [ᶢᵏǃ͡χʼṹᵑ̊ǁʰòmdímà] �...

 

Yokohama Municipal Subway

Yokohama Municipal SubwayLogoInfoWilayahYokohama, JepangJenisAngkutan cepatJumlah jalur2 (Biru dan hijau)Jumlah stasiun42Situs webwww.city.yokohama.lg.jp/koutuu/subOperasiDimulai1972 April 12 (12-16-1972)OperatorBiro Transportasi Kota YokohamaTeknisPanjang sistem534 km (332 mi)Lebar sepur1.435 mm (4 ft 8+1⁄2 in) Peta rute Map of Yokohama Municipal Subway Yokohama Municipal Subway (横浜市営地下鉄code: ja is deprecated , Yokohama-shiei chikatetsu)...

 

1621 in Ireland

This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: 1621 in Ireland – news · newspapers · books · scholar · JSTOR (May 2022) (Learn how and when to remove this message) List of events ← 1620 1619 1618 1617 1616 1621 in Ireland → 1622 1623 1624 1625 1626 Centuries: 15th 16th 17th 18th 19th Decades: 1...

Carol Cleveland

Questa voce o sezione sull'argomento attori britannici non cita le fonti necessarie o quelle presenti sono insufficienti. Puoi migliorare questa voce aggiungendo citazioni da fonti attendibili secondo le linee guida sull'uso delle fonti. Segui i suggerimenti del progetto di riferimento. Carol Cleveland Carol Cleveland (Londra, 13 gennaio 1942) è un'attrice e comica statunitense naturalizzata inglese. È nota soprattutto per la sua partecipazione agli show televisivi del gruppo comico b...

 

1995 Queensland state election

State election in Australia For the local government elections held in March, see 1995 Queensland local elections. 1995 Queensland state election ← 1992 15 July 1995 (1995-07-15) 1998 → All 89 seats in the Legislative Assembly of Queensland45 Assembly seats were needed for a majorityTurnout91.43 ( 0.05 pp)   First party Second party   N/LC Leader Wayne Goss Rob Borbidge Party Labor National–Liberal Coalition Leader since 2 March ...

 

2023 Tour of Slovenia

Cycling race 2023 Tour of Slovenia2023 UCI ProSeriesPeloton ascending on Planina (Stage 3)Race detailsDates14–18 June 2023Stages5Distance833.3 km (517.8 mi)Winning time20h 00′ 24″Results Winner  Filippo Zana (ITA) (Team Jayco–AlUla)  Second  Matej Mohorič (SLO) (Team Bahrain Victorious)  Third  Diego Ulissi (ITA) (UAE Team Emirates) Points  Ide Schelling (NED) (Bora–Hansgrohe) Mountains  Samuele Zoccarato (ITA) (...

Purwoduksino

Artikel ini tidak memiliki referensi atau sumber tepercaya sehingga isinya tidak bisa dipastikan. Tolong bantu perbaiki artikel ini dengan menambahkan referensi yang layak. Tulisan tanpa sumber dapat dipertanyakan dan dihapus sewaktu-waktu.Cari sumber: Purwoduksino – berita · surat kabar · buku · cendekiawan · JSTOR Artikel ini perlu dikembangkan agar dapat memenuhi kriteria sebagai entri Wikipedia.Bantulah untuk mengembangkan artikel ini. Jika tidak d...

 

كريج هودجز

كريج هودجز   معلومات شخصية الميلاد 27 يونيو 1960 (العمر 63 سنة)بارك فورست الطول 6 قدم 2 بوصة (1.9 م) مركز اللعب مدافع مسدد الهدف  الجنسية  الولايات المتحدة الوزن 86 كيلوغرام[1]  المدرسة الأم جامعة كاليفورنيا الحكومية في لونغ بيتش[2]  الحياة العملية الدوري ...

 

سفارة ألمانيا في مصر

سفارة ألمانيا لدى مصر ألمانيا مصر   الإحداثيات 30°03′18″N 31°13′08″E / 30.0550073°N 31.2189901°E / 30.0550073; 31.2189901   البلد مصر  المكان القاهرة العنوان 2 شارع برلين، الجبلاية، الزمالك، محافظة القاهرة· السفير فرانك هارتمان ، الاختصاص مصر  الموقع الالكتروني الموقع الرسمي...

Military ranks of Saint Kitts and Nevis

This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Military ranks of Saint Kitts and Nevis – news · newspapers · books · scholar · JSTOR (May 2021) (Learn how and when to remove this message) The Military ranks of Saint Kitts and Nevis are the military insignia used by the Saint Kitts and Nevis Defence Force. ...

 

Andrei Vasilevski (tennis)

Belarusian tennis player (born 1991) Andrei Vasilevski Андрэй ВасілеўскіCountry (sports) BelarusResidenceMinsk, BelarusBorn (1991-05-28) 28 May 1991 (age 32)Minsk, Belarusian SSR, Soviet UnionHeight1.85 m (6 ft 1 in)Turned pro2009PlaysRight-handed (two handed-backhand)CoachAliaksandr VasilevskiPrize money$411,099SinglesCareer record0-5 (at ATP Tour level, Grand Slam level, and in Davis Cup)Career titles0Highest rankingNo. 569 (...

 

Lebanese New Zealanders

Ethnic group Lebanese New ZealandersTotal population1,278 (2018 Census)[1]Regions with significant populationsAuckland and WellingtonLanguagesArabic (Lebanese Arabic), English (New Zealand English)ReligionMajority: Christian: Maronite Catholic, Greek Orthodox, Greek Catholic, Protestant Minority: Islam: Shia Islam, Sunni Islam, Alawite, Jewish and DruzeRelated ethnic groupsLebanese British, Lebanese Americans, Lebanese Canadians, Lebanese Australians Part of a series of articles onLeb...

History of the Jews in Russia

Ethnic group Russian Jews יהדות רוסיה (Hebrew) Русские евреи (Russian) רוסישע ייִדן (Yiddish) The Jewish Museum and Tolerance Center in Moscow, the largest Jewish museum in Russia.Regions with significant populationsIsrael1,200,000[1]United States350,000[2]Germany178,500[3]Russia83,896 according to the 2021 census[4]Australia10,000–11,000[5]LanguagesHebrew, Russian, YiddishReligionJudaism (31%), Jewish ...

 

Hari Kemerdekaan (Bosnia dan Herzegovina)

Hari KemerdekaanVječna vatra dihiasi dengan bendera Bosnia pada Hari Kemerdekaan 2019Nama resmiHari Kemerdekaan Bosnia dan HerzegovinaDirayakan olehFederasi Bosnia dan HerzegovinaJenisPGPGMaknaHari ketika warga negara Bosnia dan Herzegovina memilih kemerdekaan pada referendum kemerdekaan pada tahun 1992..[1]PerayaanTari, konserTanggal1 MaretFrekuensitahunan Hari Kemerdekaan Bosnia dan Herzegovina (bahasa Bosnia: Dan nezavisnosti Bosne i Hercegovine) adalah hari libur umum yang di...