Midazolam

Midazolam
Formula kimikoaC18H13ClFN3
SMILES kanonikoa2D eredua
MolView3D eredua
MotaBentzodiazepina
Masa molekularra325,078 Da
Erabilera
Konposatu aktiboaBuccolam (en) Itzuli
Tratatzen duantsietate-nahasmendu, agitation in dementia (en) Itzuli eta status epilepticus (en) Itzuli
Interakzioakpetidina, petidina, periciazine (en) Itzuli, tramadol, tramadol, Metadona, Metadona, Morfina, Morfina, Oxikodona, Oxikodona, hydromorphone (en) Itzuli, hydromorphone (en) Itzuli, dihydrocodeine (en) Itzuli, dihydrocodeine (en) Itzuli, Kodeina, Kodeina, tapentadol (en) Itzuli, tapentadol (en) Itzuli, Buprenorfina, fentanil, mirtazapine (en) Itzuli, Alfentanilo, Alfentanilo, Alfentanilo, Sufentanilo, Sufentanilo, (±)-thiopental (en) Itzuli, Fenobarbital, sodium oxybate (en) Itzuli, loxapine (en) Itzuli, loxapine (en) Itzuli, loxapine (en) Itzuli, loxapine (en) Itzuli, loxapine (en) Itzuli, itraconazole (en) Itzuli, Erritonabir eta Erritonabir
ElkarrekintzaAlpha-1B adrenergic receptor (en) Itzuli
HaurdunaldiaAustralian pregnancy category C (en) Itzuli eta US pregnancy category D (en) Itzuli
RolaGABAA receptor positive allosteric modulators (en) Itzuli, hypnotics and sedatives (en) Itzuli, Antsiolitiko, GABA Modulators (en) Itzuli, anesthesia adjuvants (en) Itzuli, intravenous anesthetics (en) Itzuli, farmako esentzial eta Bentzodiazepina
Identifikatzaileak
InChlKeyDDLIGBOFAVUZHB-UHFFFAOYSA-N
CAS zenbakia59467-70-8
ChemSpider4047
PubChem4192
Gmelin6931
ChEMBLCHEMBL655
EC zenbakia261-774-5
ECHA100.056.140
MeSHD008874
RxNorm6960
Human Metabolome DatabaseHMDB0014821
UNIIR60L0SM5BC
NDF-RTN0000147927
KEGGC07524 eta D00550
PDB Ligand08J
Ohar medikoa
Ohar medikoa
Oharra: Wikipediak ez du mediku aholkurik ematen. Tratamendua behar duzula uste baduzu, jo ezazu sendagilearengana.

Midazolam[1] erdibizitza laburreko bentzodiazepina da. Eragin antsiolitiko, hipnotiko, amnesiko, konbultsiokontrako, muskulu erlaxatzaile eta segarriak ditu.

Midazolam uretan disolbagarria den bentzodiazepina bakarra da, gainerakoak liposolugarriak baitira. Bere erdibizitza 2 ordu ingurukoa da eta honek bere erabilpen terapeutikoan zeresana izango du.

Erabilera terapeutikoa

Anestesia orokorraren aurremedikazio gisa erabiltzen da kirurgian, sedazioa eragiten baitu.

Bestalde, zenbait herrialdetan insomnioaren tratamenduan ere erabiltzen da.

Eragin desiragaitzak

  • Ajea
  • Asaldura psikomotoreak
  • Funtzio kognitiboen asaldura

Kontraindikazioak

Erreferentziak

  1. ↑ Gipuzkoako Sendagileen Elkargo Ofiziala. Hiztegia. .

Kanpo estekak

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