William Pearson (scientist)

William R Pearson
Born
William Raymond Pearson
Education
Known forFASTA[6][7][8]
AwardsAAAS Fellow (2008)[1]
ISCB Fellow (2018)[2]
Scientific career
FieldsComputational biology[3]
InstitutionsUniversity of Virginia
ThesisStudies on the arrangement of repeated sequences in DNA (1977)
Websitefasta.bioch.virginia.edu/wrpearson

William Raymond Pearson is professor of biochemistry and molecular Genetics in the School of Medicine[3][9] at the University of Virginia.[10][11][12] Pearson is best known for the development of the FASTA format.

Education

Pearson graduated with a BS in chemistry from the University of Illinois Urbana-Champaign. He received his PhD in 1977 from Caltech.[5] As a graduate student, he published several papers describing computer programs for analyzing biological data.[13][14]

Career and research

After his PhD, Pearson did a postdoctoral fellowship at Johns Hopkins University. In 1983, he joined the faculty of Biochemistry at the University of Virginia School of Medicine.[10] Immediately after joining the faculty, he collaborated with David J. Lipman at the NIH to write the FASTP program,[7] and later FASTA.[8] Pearson's research interests are in computational biology.[3] He was named an American Association for the Advancement of Science (AAAS) Fellow in 2008, and an International Society for Computational Biology (ISCB) Fellow in 2018 for outstanding contributions to the fields of computational biology and bioinformatics. [1] [2]

References

  1. ^ a b Anon (2008). "AAAS fellows". www.aaas.org.
  2. ^ a b Anon (2018). "ISCB Fellows". iscb.org. International Society for Computational Biology.
  3. ^ a b c William Pearson publications indexed by Google Scholar Edit this at Wikidata
  4. ^ William Pearson's ORCID 0000-0002-0727-3680
  5. ^ a b Pearson, William Raymond (1977). Studies on the arrangement of repeated sequences in DNA (PhD thesis). OCLC 637417263. ProQuest 302832904.
  6. ^ Pearson, William R. (1990). [5] Rapid and sensitive sequence comparison with FASTP and FASTA. Methods in Enzymology. Vol. 183. pp. 63–98. doi:10.1016/0076-6879(90)83007-V. ISBN 9780121820848. ISSN 0076-6879. PMID 2156132. Closed access icon
  7. ^ a b Lipman, D.; Pearson, W. (1985). "Rapid and sensitive protein similarity searches". Science. 227 (4693): 1435–1441. Bibcode:1985Sci...227.1435L. doi:10.1126/science.2983426. ISSN 0036-8075. PMID 2983426. Closed access icon
  8. ^ a b Pearson, W. R.; Lipman, D. J. (1988). "Improved tools for biological sequence comparison". Proceedings of the National Academy of Sciences of the United States of America. 85 (8): 2444–2448. Bibcode:1988PNAS...85.2444P. doi:10.1073/pnas.85.8.2444. PMC 280013. PMID 3162770.
  9. ^ "Biochemistry Research - Pearson". fasta.bioch.virginia.edu/wrpearson.
  10. ^ a b "Pearson, William R." med.virginia.edu.
  11. ^ "Biomedical Sciences Graduate Program - William R. Pearson". bims.virginia.edu.
  12. ^ William Pearson publications indexed by the Scopus bibliographic database. (subscription required)
  13. ^ Garrard, WT; Pearson, WR; Wake, SK; Bonner, J (1974). "Stoichiometry of chromatin proteins". Biochemical and Biophysical Research Communications. 58 (1): 50–57. doi:10.1016/0006-291x(74)90889-4. PMID 4831079.
  14. ^ Pearson, WR; Davidson, EH; Britten, RJ (1977). "A program for least squares analysis of reassociation and hybridization data". Nucleic Acids Research. 4 (6): 1727–1737. doi:10.1093/nar/4.6.1727. PMC 342517. PMID 896473.