Search Results: Receptor desensitization


Receptor
Rabu, 2025-01-08 05:30:56

Look up receptor in Wiktionary, the free dictionary. Receptor may refer to: Sensory receptor, in physiology, any neurite structure that, on receiving environmental...

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Receptor (biochemistry)
Sabtu, 2026-05-16 00:35:41

In biochemistry and pharmacology, receptors are proteins that receive and transduce signals that may be integrated into biological systems. These signals...

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Antihistamine
Rabu, 2026-07-15 01:31:22

receptor and heightens the receptor's activity; the receptor antagonists work by binding to the receptor and blocking the activation of the receptor by...

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Adrenergic receptor
Rabu, 2026-06-17 02:25:46

The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)...

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Receptor antagonist
Selasa, 2026-08-04 08:20:06

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than...

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Opioid receptor
Kamis, 2026-04-30 22:29:31

Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...

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Androgen receptor
Rabu, 2025-10-22 12:06:49

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by...

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Cannabinoid receptor
Minggu, 2026-08-02 06:52:26

Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system of vertebrates– a class of cell membrane receptors in the G protein-coupled...

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NMDA receptor
Sabtu, 2026-06-20 09:31:42

receptor (also known as the NMDA receptor or NMDAR) is a glutamate receptor and a predominantly Ca2+ ion channel found in neurons. The NMDA receptor is...

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GABAA receptor
Sabtu, 2026-07-18 07:12:24

The GABAA receptor (GABAAR) is an ionotropic receptor (i.e., ligand-gated ion channel). Its endogenous ligand is γ-aminobutyric acid (GABA), the major...

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5-HT2A receptor
Kamis, 2026-08-06 09:18:27

5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)...

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Agonist
Jumat, 2026-07-03 06:36:42

An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to...

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Alpha-2 adrenergic receptor
Kamis, 2026-05-07 05:18:45

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists...

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Imidazoline receptor
Selasa, 2025-09-30 22:57:59

Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act. There are three main classes of imidazoline receptor: I1 is...

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Beta blocker
Rabu, 2026-07-22 15:30:45

blockers, also spelled β-blockers and also sometimes known as β-adrenergic receptor antagonists, are a class of medications predominantly used to manage abnormal...

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GLP-1 receptor agonist
Sabtu, 2026-07-25 17:10:32

Glucagon-like peptide-1 (GLP-1) receptor agonists, also known as GLP-1 agonists, GLP-1RAs, and informally as simply GLP-1s, are a class of medications...

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Mu-opioid receptor
Rabu, 2026-06-03 23:34:46

The μ-opioid receptors (using the Greek letter mu, abbreviated MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin...

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Nicotinic acetylcholine receptor
Kamis, 2026-07-23 04:32:29

acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to...

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Muscarinic acetylcholine receptor
Jumat, 2026-06-26 21:52:11

Muscarinic acetylcholine receptors (mAChRs) are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain...

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Androgen insensitivity syndrome
Jumat, 2026-04-03 20:46:15

involving the inability to respond to androgens, typically due to androgen receptor dysfunction. It affects 1 in 20,000 to 64,000 XY (karyotypically male)...

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P2 receptor
Minggu, 2023-09-17 21:35:55

P2 receptor may refer to: Nucleotides, if released into the extracellular environment, can lead to cell death or other harmful cellular consequences. To...

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Cell surface receptor
Kamis, 2026-07-16 10:08:08

Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells. They act in cell...

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Scavenger receptor
Sabtu, 2016-10-22 19:53:57

Scavenger receptor may refer to: Scavenger receptor (immunology) Scavenger receptor (endocrinology) This disambiguation page lists articles associated...

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Receptor editing
Senin, 2025-03-10 02:55:29

Receptor editing is a process that occurs during the maturation of B cells, which are part of the adaptive immune system. This process forms part of central...

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Cannabinoid
Kamis, 2026-07-23 05:33:24

specific membrane-bound receptors. The discovery of cannabinoid receptors in the 1980s resolved this debate. These receptors are common in animals, with...

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Opioid
Minggu, 2026-08-09 18:05:58

natural substances found in the opium poppy plant. Opioids work on opioid receptors in the brain and other organs to produce a variety of morphine-like effects...

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Receptor degrader
Jumat, 2025-12-19 03:28:28

A receptor degrader binds to a receptor and induces its breakdown, causing down-regulation of signaling of that receptor. It is distinct from the mechanism...

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Hypnotic
Sabtu, 2026-08-08 00:53:59

histamine H1 receptor antagonism, serotonin 5-HT2A receptor antagonism, α1-adrenergic receptor antagonism, and/or dopamine D2 receptor antagonism. While...

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Orexin antagonist
Jumat, 2026-06-26 12:08:32

of one (selective orexin receptor antagonist or SORA) or both (dual orexin receptor antagonist or DORA) of the orexin receptors, OX1 and OX2. Medical applications...

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Psychedelic drug
Senin, 2026-08-10 01:32:32

to and activating a receptor in the brain called the serotonin 5-HT2A receptor, and hence are a type of serotonin 5-HT2A receptor agonist. By activating...

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Orexin receptor
Sabtu, 2026-08-08 08:45:13

The orexin receptor (also referred to as the hypocretin receptor) is a G-protein-coupled receptor that binds the neuropeptide orexin. There are two variants...

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Alpha-1 adrenergic receptor
Selasa, 2026-07-21 08:47:56

The alpha-1 (α1) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G protein. It consists...

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Niacin receptor
Jumat, 2022-07-22 09:08:05

niacin receptors (or nicotinic acid receptors, abbreviated NIACR) are: Niacin receptor 1 (NIACR1, formerly known as GPR109A) Niacin receptor 2 (NIACR2...

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NMDA receptor antagonist
Minggu, 2026-08-02 05:03:14

NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the N-methyl-D-aspartate receptor (NMDAR). They are commonly...

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G protein-coupled receptor
Sabtu, 2026-07-18 03:47:00

protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G...

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Fc receptor
Kamis, 2026-04-09 15:31:03

In immunology, an Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells,...

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Taste receptor
Rabu, 2026-07-15 13:41:59

A taste receptor is a type of cellular receptor that facilitates the sensation of taste. When food or other substances enter the mouth, molecules interact...

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5-HT1A receptor
Senin, 2026-07-27 12:45:05

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter...

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Dopamine receptor
Selasa, 2026-06-23 02:43:19

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate...

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Hydroxycarboxylic acid receptor
Minggu, 2023-08-13 11:35:44

hydroxycarboxylic acid receptor (abbreviated HCA receptor and HCAR) family includes the following human proteins: Hydroxycarboxylic acid receptor 1 (HCA1, formerly...

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Dopamine receptor D2
Kamis, 2026-05-14 23:38:40

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard's lab had suggested...

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Hormone receptor positive breast cancer
Jumat, 2026-01-30 14:32:12

A hormone-receptor-positive (HR+) tumor is a tumor which consists of cells that express receptors for certain hormones. The term most commonly refers...

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CAR T cell
Senin, 2026-07-27 12:39:31

antigen receptor T cells (CAR T cells)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor proteins...

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Receptor theory
Rabu, 2025-09-10 05:09:18

Receptor theory is the application of receptor models to explain drug behavior. Pharmacological receptor models preceded accurate knowledge of receptors...

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AMPA receptor
Rabu, 2026-05-06 12:02:46

acid receptor (AMPA receptor, AMPAR, or quisqualate receptor) is a nonselective ionotropic glutamate receptor (iGluR) that mediates fast...

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Acetylcholine receptor
Selasa, 2026-07-21 23:48:54

An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine,...

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Sigma-1 receptor
Sabtu, 2026-07-04 05:11:11

The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling...

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Downregulation and upregulation
Minggu, 2026-05-17 15:09:38

downregulation is the cellular decrease in the expression of a specific receptor in response to its increased activation by a molecule, such as a hormone...

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Ligand (biochemistry)
Jumat, 2026-07-31 18:03:14

the function of the receptor that triggers a physiological response is called a receptor agonist. Ligands that bind to a receptor but fail to activate...

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TRPV1
Kamis, 2026-06-04 22:13:18

transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein...

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Receptor tyrosine kinase
Sabtu, 2026-07-04 08:54:04

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...

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Olfactory receptor
Kamis, 2026-07-30 18:16:31

Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible...

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Angiotensin II receptor blocker
Sabtu, 2026-08-08 06:07:13

Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT1) antagonists, also known as angiotensin receptor blockers, angiotensin...

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Anti-NMDA receptor encephalitis
Rabu, 2026-06-03 02:24:11

Anti-NMDA receptor encephalitis is a type of brain inflammation caused by antibodies. Early symptoms may include fever, headache, and feeling tired. This...

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Glycine receptor
Kamis, 2026-03-12 05:19:54

The glycine receptor (abbreviated as GlyR or GLR) is the receptor of the amino acid neurotransmitter glycine. GlyR is an ionotropic receptor that produces...

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5-HT receptor
Sabtu, 2026-07-11 19:35:13

5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in...

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Cell signaling
Minggu, 2026-08-09 02:18:03

process involves three components: the first messenger (the ligand), the receptor, and the signal itself. In biology, signals are mostly chemical in nature...

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RAGE (receptor)
Rabu, 2026-07-08 09:41:05

RAGE (receptor for advanced glycation end-products), also called AGER, is a 35 kilodalton transmembrane receptor of the immunoglobulin super family which...

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GABAB receptor
Sabtu, 2026-07-18 22:39:07

GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA). GABAB receptors are found in the central nervous system and...

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Serotonin 5-HT2A receptor agonist
Minggu, 2026-08-09 16:28:51

5-HT2A receptor agonist, or simply 5-HT2A agonist, is a drug which acts as an agonist of the serotonin 5-HT2A receptor. The serotonin 5-HT2A receptor is one...

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Serotonin receptor agonist
Rabu, 2026-07-08 15:05:10

A serotonin receptor agonist is an agonist of one or more serotonin receptors. They activate serotonin receptors in a manner similar to that of serotonin...

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GABA receptor
Senin, 2025-09-29 14:24:56

of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled...

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Retatrutide
Jumat, 2026-08-07 09:30:05

and Company. It is a triple hormone receptor agonist on the GLP-1, GIP, and glucagon receptors. GLP-1 receptors improve insulin sensitivity and increase...

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GABA receptor agonist
Rabu, 2026-06-17 01:17:51

A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other...

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Adenosine receptor
Sabtu, 2025-11-01 07:04:51

The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as the endogenous ligand. There are four...

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Nuclear receptor
Sabtu, 2026-06-13 03:04:53

In the field of molecular biology, nuclear receptors are a class of proteins responsible for sensing steroids, thyroid hormones, vitamins, and certain...

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Pharmacology
Senin, 2026-08-10 05:30:00

broad terms, pharmacodynamics discusses the chemicals with biological receptors, and pharmacokinetics discusses the liberation, absorption, distribution...

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Melanocortin 1 receptor
Senin, 2026-06-29 12:16:37

melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a...

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Juxtacapillary receptors
Minggu, 2025-09-21 00:52:11

Juxtacapillary receptors, J-receptors, or pulmonary C-fiber receptors are sensory nerve endings located within the alveolar walls in juxtaposition to the...

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5-HT3 receptor
Selasa, 2026-07-21 22:08:29

The 5-HT3 receptors are a subclass of serotonin receptors. They belong to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and differ structurally...

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Alpha-7 nicotinic receptor
Sabtu, 2026-07-04 02:36:09

The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor implicated in long-term memory, consisting...

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Ligand-gated ion channel
Minggu, 2026-06-21 02:30:59

Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow...

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Cannabinoid receptor 1
Minggu, 2026-07-19 08:09:31

Cannabinoid receptor 1 (CB1), is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. It was discovered by determination...

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Neurotransmitter
Senin, 2026-08-10 03:10:40

Voltage- gated Ca++ channel Synaptic vesicle Neurotransmitter transporter Receptor Neurotransmitter Axon terminal Synaptic cleft Dendrite A neurotransmitter...

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Signaling peptide receptor
Rabu, 2024-08-21 03:05:17

peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins. An example is the tropomyosin receptor kinase...

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Estrogen receptor
Minggu, 2026-08-09 08:28:15

Estrogen receptors (ERs) are proteins found in cells that function as receptors for the hormone estrogen (17β-estradiol). There are two main classes of...

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Δ-opioid receptor
Minggu, 2026-06-07 03:25:09

The δ-opioid receptor, also known as delta opioid receptor or simply delta receptor, abbreviated DOR or DOP, is an inhibitory 7-transmembrane G-protein...

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Cetirizine
Rabu, 2026-07-22 13:32:52

because second-generation antihistamines are more selective for the H1 receptor. Compared to other second-generation antihistamines, cetirizine can cause...

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Histamine H1 receptor
Selasa, 2026-05-19 02:24:59

The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors. This receptor is activated by the biogenic...

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Insulin receptor substrate
Rabu, 2026-02-25 20:28:27

insulin receptor contains a NPXY motif. The PTB-domain binds the NPXY sequence. Thus, the insulin receptor binds IRS. IRS1 (see also Insulin receptor substrate...

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Estrogen receptor alpha
Senin, 2026-06-29 07:52:31

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear...

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Decoy receptors
Selasa, 2026-05-12 04:03:11

A decoy receptor is a receptor that is able to recognize and bind specific ligands efficiently, but is not able to support its intended function. This...

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Ryanodine receptor
Senin, 2026-06-15 00:49:04

Ryanodine receptors (RyR) are classified as high-conductance, intracellular calcium release channels, typically present in the membrane of the sarcoplasmic...

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Graves' disease
Kamis, 2026-08-06 15:18:06

disease is unclear, but symptoms are a result of antibodies binding to receptors on the thyroid, causing over-expression of thyroid hormone. Persons are...

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Receptor-mediated endocytosis
Senin, 2026-01-26 11:29:35

Receptor-mediated endocytosis (RME), also called clathrin-mediated endocytosis, is a process by which cells absorb metabolites, hormones, proteins – and...

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Scavenger receptor (immunology)
Minggu, 2025-11-23 05:36:37

Scavenger receptors are a large and diverse superfamily of cell surface receptors. Its properties were first recorded in 1970 by Drs. Brown and Goldstein...

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Complement receptor
Sabtu, 2025-07-19 12:28:43

complement receptor is a membrane-bound receptor belonging to the complement system, which is part of the innate immune system. Complement receptors bind effector...

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Muscarinic acetylcholine receptor M1
Sabtu, 2026-07-25 22:25:25

The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by...

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Progesterone receptor
Minggu, 2026-05-24 02:49:24

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated...

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Muscarinic antagonist
Rabu, 2026-08-05 00:33:54

A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic...

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Soluble transferrin receptor
Senin, 2023-08-14 02:56:51

transferrin receptor conventionally refers to the cleaved extracellular portion of transferrin receptor 1 that is released into serum. This receptor is a protein...

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Anticholinergic
Sabtu, 2026-07-11 19:23:54

parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible...

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Κ-opioid receptor
Senin, 2026-07-27 13:38:07

The κ-opioid receptor or kappa opioid receptor, abbreviated KOR or KOP for its ligand ketazocine, is a G protein-coupled receptor that is encoded by the...

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Glucocorticoid receptor
Rabu, 2026-04-15 13:14:55

glucocorticoid receptor (GR or GCR) also known by its gene name NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the steroid receptor for glucocorticoids...

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Amylin receptor
Jumat, 2026-08-07 14:58:20

The amylin receptors (AMYRs) are a family of 3 receptors that are activated by amylin, a peptide hormone secreted together with insulin. They are each...

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5-HT1B receptor
Rabu, 2026-07-29 09:20:49

5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene. The 5-HT1B receptor is a 5-HT receptor subtype...

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Glucagon-like peptide-1
Senin, 2026-07-27 21:36:32

is preserved in patients with type 2 diabetes. Glucagon-like peptide-1 receptor agonists gained approval as drugs to treat diabetes and obesity starting...

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5-HT6 receptor
Jumat, 2026-03-20 07:02:10

The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT). It is a G protein-coupled...

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Hormone receptor
Selasa, 2026-06-23 07:46:05

hormone receptor is a receptor molecule that binds to a specific hormone. Hormone receptors are a wide family of proteins made up of receptors for thyroid...

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Cannabinoid receptor 2
Selasa, 2026-03-17 09:21:25

The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It...

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T-cell receptor
Senin, 2026-05-25 03:18:42

The T-cell receptor (TCR) is a protein complex, located on the surface of T cells (also called T lymphocytes). They are responsible for recognizing fragments...

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Dopamine antagonist
Sabtu, 2026-06-20 01:23:22

anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics...

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Paired receptors
Senin, 2025-10-06 10:31:35

Paired receptors are pairs or clusters of receptor proteins that bind to extracellular ligands but have opposing activating and inhibitory signaling effects...

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Olfactory receptor neuron
Sabtu, 2026-08-01 13:24:11

An olfactory receptor neuron (ORN), also called an olfactory sensory neuron (OSN), is a sensory neuron within the olfactory system. ORNs are the principal...

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Angiotensin II receptor
Senin, 2025-10-27 12:56:01

The angiotensin II receptors, (ATR1) and (ATR2), are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in...

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5-HT2C receptor
Kamis, 2026-08-06 09:12:47

The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2...

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Folate receptor
Sabtu, 2026-02-21 22:50:16

Folate receptors bind folate and reduced folic acid derivatives and mediate delivery of tetrahydrofolate to the interior of cells. It is then converted...

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Opioid antagonist
Minggu, 2026-07-12 11:58:35

opioid receptor antagonist, is a receptor antagonist that acts on one or more of the opioid receptors. Opioid antagonists can work on receptors in the...

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Sigma-2 receptor
Selasa, 2026-03-24 06:09:14

The sigma-2 receptor (σ2R) is a sigma receptor subtype that has attracted attention due to its involvement in diseases such as neurological diseases, neurodegenerative...

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Melatonin receptor agonist
Minggu, 2025-12-21 17:46:00

Melatonin receptor agonists are analogues of melatonin that bind to and activate the melatonin receptor. Agonists of the melatonin receptor have a number...

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Tropomyosin receptor kinase B
Minggu, 2026-07-19 10:50:36

Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type...

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Oxytocin receptor
Jumat, 2026-07-24 10:30:00

The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. In humans, the oxytocin...

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Trk receptor
Sabtu, 2026-07-11 12:32:13

Trk receptors are a family of tyrosine kinases that regulates synaptic strength and plasticity in the mammalian nervous system. Trk receptors affect neuronal...

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Estrogen receptor test
Senin, 2024-07-01 02:38:36

The estrogen receptor test (ERT) is a laboratory test to determine whether cancer cells have estrogen receptors. This information can guide treatment of...

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Insulin receptor
Minggu, 2026-04-26 03:59:00

The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase...

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Non-catalytic tyrosine-phosphorylated receptor
Senin, 2025-03-03 14:55:21

tyrosine-phosphorylated receptors (NTRs), also called immunoreceptors or Src-family kinase-dependent receptors, are a group of cell surface receptors expressed by...

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Alpha-adrenergic agonist
Minggu, 2026-08-09 00:14:59

selectively stimulate alpha adrenergic receptors. The alpha-adrenergic receptor has two subclasses, α1 and α2. Alpha 2 receptors are associated with sympatholytic...

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B-cell receptor
Jumat, 2026-08-07 21:01:48

The B-cell receptor (BCR) is a transmembrane protein on the surface of a B cell. A B-cell receptor is composed of a membrane-bound immunoglobulin molecule...

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Melanocortin 4 receptor
Senin, 2026-07-27 13:49:05

The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor involved in regulating energy homeostasis, appetite, and sexual function. It plays...

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Losartan
Minggu, 2026-06-28 17:06:08

to treat high blood pressure (hypertension). It is in the angiotensin receptor blocker (ARB) family of medication, and is considered protective of the...

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Glutamate receptor
Rabu, 2026-05-20 22:20:23

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base...

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Dependence receptor
Minggu, 2025-11-23 22:18:41

In cellular biology, dependence receptors are proteins that mediate programmed cell death by monitoring the absence of certain trophic factors (or, equivalently...

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Erythropoietin receptor
Rabu, 2025-10-22 02:48:42

The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. EpoR is a 52 kDa peptide with a single carbohydrate chain resulting...

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Neurotransmitter receptor
Kamis, 2026-05-07 13:18:50

A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside...

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Glucagon receptor
Senin, 2025-10-13 10:22:07

glucagon receptor is a 62 kDa protein that is activated by glucagon and is a member of the class B G-protein coupled family of receptors (secretin receptor family)...

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Sulfonylurea receptor
Kamis, 2024-11-28 03:30:20

In molecular biology, the sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of antidiabetic...

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Mineralocorticoid receptor antagonist
Senin, 2026-03-23 22:29:13

A mineralocorticoid receptor antagonist (MRA or MCRA) or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid...

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Toll-interleukin receptor
Senin, 2025-10-06 02:23:40

receptor/Resistance protein (TIR) homology domain is an intracellular signaling domain found in MyD88, SARM1, interleukin-1 receptors, toll receptors...

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Adenosine A2A receptor
Selasa, 2026-06-30 12:35:23

The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it. This protein is a member of...

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Ectodysplasin A receptor
Rabu, 2025-11-12 02:50:20

Ectodysplasin A receptor (EDAR) is a protein that in humans is encoded by the EDAR gene. EDAR is a cell surface receptor for ectodysplasin A which plays...

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Vasopressin receptor 1B
Minggu, 2025-07-27 11:04:38

Vasopressin V1b receptor (V1BR) also known as vasopressin 3 receptor (VPR3) or antidiuretic hormone receptor 1B is a protein that in humans is encoded...

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IL1RL2
Kamis, 2025-07-17 00:36:28

receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene. The protein encoded by this gene is a member of the interleukin 1 receptor...

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Histamine H4 receptor
Kamis, 2026-05-21 14:38:37

The histamine H4 receptor, like the other three histamine receptors, is a member of the G protein-coupled receptor superfamily that in humans is encoded...

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Bombesin receptor
Sabtu, 2025-09-13 17:07:37

The bombesin receptors are a group of G-protein coupled receptors which bind bombesin. Three bombesin receptors are currently known: BB1, previously known...

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Glucagon-like peptide-1 receptor
Selasa, 2026-07-07 15:31:32

The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...

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Outer membrane receptor
Minggu, 2026-02-08 03:53:41

Outer membrane receptors, also known as TonB-dependent receptors, are a family of beta barrel proteins named for their localization in the outer membrane...

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Sex-hormonal agent
Jumat, 2024-05-10 06:19:22

A sex-hormonal agent, also known as a sex-hormone receptor modulator, is a type of hormonal agent which specifically modulates the effects of sex hormones...

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Sigma receptor
Kamis, 2026-07-09 05:44:30

Sigma receptors (σ-receptors) are protein receptors that bind ligands such as 4-PPBP (4-phenyl-1-(4-phenylbutyl) piperidine), SA 4503 (cutamesine), ditolylguanidine...

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Mannose receptor
Kamis, 2026-07-23 03:24:20

The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells...

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Transduction (physiology)
Kamis, 2025-02-06 08:11:45

potential by a sensory receptor. It begins when stimulus changes the membrane potential of a sensory receptor. A sensory receptor converts the energy in...

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GABAA receptor agonist
Senin, 2026-07-06 21:22:39

A GABAA receptor agonist is a drug that acts as an orthosteric agonist of the GABAA receptor, the major signaling receptor of the inhibitory neurotransmitter...

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VLDL receptor
Jumat, 2026-02-27 14:16:18

very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable...

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Muscarinic agonist
Rabu, 2026-05-20 13:54:35

acetylcholine receptor agonist, also known as a muscarinic agonist or as a muscarinic agent, is an agent that activates the muscarinic acetylcholine receptor. The...

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Dopamine receptor D1
Jumat, 2026-06-12 14:24:42

Dopamine receptor D1, also known as DRD1, is one of the two types of D1-like receptor family—receptors D1 and D5. It is a protein that in humans is encoded...

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Phencyclidine
Jumat, 2026-07-10 02:57:35

member of the arylcyclohexylamine class. PCP works primarily as an NMDA receptor antagonist. PCP is most commonly used in the US. While usage peaked in...

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Receptor–ligand kinetics
Sabtu, 2026-05-23 23:37:08

denoted as receptor(s) and ligand(s). Receptor–ligand binding kinetics also involves the on- and off-rates of binding. A main goal of receptor–ligand kinetics...

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Receptor modulator
Kamis, 2025-11-06 06:20:37

A receptor modulator, or receptor ligand, is a general term for a substance, endogenous or exogenous, that binds to and regulates the activity of chemical...

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Leptin receptor
Minggu, 2025-09-28 08:28:57

Leptin receptor, also known as LEP-R or OB-R, is a type I cytokine receptor, a protein that in humans is encoded by the LEPR gene. LEP-R functions as a...

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Protease-activated receptor
Selasa, 2025-11-25 18:44:07

Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular...

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Ephrin receptor
Minggu, 2025-10-19 11:59:14

Eph receptors (Ephs, after erythropoietin-producing human hepatocellular receptors) are a group of receptors that are activated in response to binding...

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TRPM8
Senin, 2026-04-20 13:42:09

Transient receptor potential cation channel subfamily M (melastatin) member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein...

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Mirtazapine
Rabu, 2026-08-05 13:05:46

not clear, but it may involve blocking certain adrenergic and serotonin receptors. Chemically, it is a tetracyclic antidepressant, and is closely related...

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Ryanodine receptor 3
Rabu, 2024-07-17 05:42:05

Ryanodine receptor 3 is one of a class of ryanodine receptors and a protein that in humans is encoded by the RYR3 gene. The protein encoded by this gene...

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Metabotropic glutamate receptor
Minggu, 2026-08-09 08:32:31

The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members...

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Epidermal growth factor receptor
Sabtu, 2026-07-18 13:57:26

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth...

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Fas receptor
Jumat, 2026-07-24 12:33:41

Fas receptor, also known as Fas, FasR, apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily...

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Urokinase receptor
Minggu, 2025-03-30 18:26:05

The Urokinase receptor, also known as urokinase plasminogen activator surface receptor (uPAR) or CD87 (Cluster of Differentiation 87), is a protein encoded...

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List of investigational insomnia drugs
Sabtu, 2026-08-08 07:53:32

and MT2 receptor agonist Brexpiprazole (Rexulti; Lu-AF41156; OPC-34712; OPDC-34712) – atypical antipsychotic (non-selective monoamine receptor modulator)...

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Prolactin receptor
Rabu, 2026-06-24 13:19:13

The prolactin receptor (PRLR) is a type I cytokine receptor encoded in humans by the PRLR gene on chromosome 5p13-14. It is the receptor for prolactin...

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Phagocytosis
Selasa, 2026-06-23 11:21:32

Macrophages initiate phagocytosis by mannose receptors, scavenger receptors, Fcγ receptors and complement receptors 1, 3 and 4. Macrophages are long-lived and...

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NPR1
Jumat, 2025-07-18 00:39:40

peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is an atrial natriuretic peptide receptor. In humans...

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Adrenergic antagonist
Rabu, 2025-12-24 14:23:41

receptors. There are five adrenergic receptors, which are divided into two groups. The first group of receptors are the beta (β) adrenergic receptors...

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Dopaminergic
Rabu, 2026-06-17 01:52:26

dopamine receptors can be classified as dopaminergic, and neurons that synthesize or contain dopamine and synapses with dopamine receptors in them may...

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Interleukin 1 receptor, type I
Kamis, 2025-10-02 00:30:16

Interleukin 1 receptor, type I (IL1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL1R1 also denotes its human...

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Beta-2 adrenergic receptor
Minggu, 2026-04-12 17:47:46

The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline)...

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Dopamine agonist
Selasa, 2026-06-23 02:43:16

A dopamine agonist is a compound that activates dopamine D2 receptors and belong to one of two different subclasses: ergoline and non-ergoline. Examples...

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Thrombin receptor
Rabu, 2024-12-11 21:59:04

three known thrombin receptors (ThrR), termed PAR1, PAR3 and PAR4 (PAR for protease-activated receptor). G-protein-coupled receptors that are responsible...

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Neurotrophic factor receptor
Kamis, 2025-04-10 17:25:52

Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors)...

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Toll-like receptor
Selasa, 2026-05-12 00:31:34

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-spanning receptors usually expressed...

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Enzyme-linked receptor
Kamis, 2026-05-07 05:40:39

An enzyme-linked receptor, also known as a catalytic receptor, is a transmembrane receptor, where the binding of an extracellular ligand causes enzymatic...

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List of investigational antidepressants
Jumat, 2026-08-07 03:34:20

ionotropic glutamate NMDA receptor glycine site partial agonist and atypical antipsychotic (non-selective monoamine receptor modulator) combination Deupsilocin...

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Vomeronasal receptor
Sabtu, 2026-07-11 22:44:38

Vomeronasal receptors are a class of olfactory receptors that putatively function as receptors for pheromones. Pheromones have evolved in all animal phyla...

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Thyroid hormone receptor
Jumat, 2026-06-05 03:18:12

The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone. TRs act as transcription factors, ultimately...

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Neuropeptide Y receptor
Jumat, 2026-07-24 18:17:10

Neuropeptide Y receptors are a family of receptors belonging to class A G-protein coupled receptors and they are activated by the closely related peptide...

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Transferrin receptor
Senin, 2026-07-27 07:57:17

Transferrin receptor (TfR) is a carrier protein for transferrin. It is needed for the import of iron into cells and is regulated in response to intracellular...

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ACVRL1
Jumat, 2025-08-08 16:42:26

Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene. ACVRL1 is a receptor in the TGF beta signaling pathway...

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Histamine H2 receptor
Kamis, 2025-12-11 23:45:49

H2 receptors are a type of histamine receptor found in many parts of the anatomy of humans and other animals. They are positively coupled to adenylate...

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Dopamine receptor D4
Selasa, 2026-07-07 11:21:53

The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of DRD4 has...

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Monoamine receptor
Senin, 2023-11-06 18:14:18

A monoamine receptor is a receptor for the monoamine neurotransmitters and/or trace amines, endogenous small-molecule signaling molecules with a monoamine...

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VEGF receptor
Selasa, 2025-06-24 15:47:51

VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...

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Chemokine receptor
Jumat, 2026-07-10 22:15:40

Chemokine receptors are cytokine receptors found on the surface of certain cells that interact with a type of cytokine called a chemokine. There have been...

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Death receptor 5
Senin, 2026-03-02 12:57:34

Death receptor 5 (DR5), also known as TRAIL receptor 2 (TRAILR2) and tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), is a cell surface...

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Luteinizing hormone/choriogonadotropin receptor
Senin, 2026-06-15 14:46:20

hormone/choriogonadotropin receptor (LHCGR), also lutropin/choriogonadotropin receptor (LCGR) or luteinizing hormone receptor (LHR), is a transmembrane receptor found predominantly...

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Folate receptor 1
Selasa, 2026-06-16 23:01:42

Folate receptor 1 (Folate receptor alpha, FOLR1) is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member...

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Beta-1 adrenergic receptor
Sabtu, 2026-07-18 15:51:13

receptor (β1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors....

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Membrane mineralocorticoid receptor
Senin, 2024-01-01 10:32:18

Membrane mineralocorticoid receptors (mMRs) or membrane aldosterone receptors are a group of receptors which bind and are activated by mineralocorticoids...

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D1-like receptor
Kamis, 2025-12-11 08:39:19

The D1-like receptors are a subfamily of dopamine receptors that bind the endogenous neurotransmitter dopamine. The D1-like subfamily consists of two...

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Muscarinic acetylcholine receptor M3
Senin, 2026-07-13 00:33:13

acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the...

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GABAA-rho receptor
Rabu, 2026-05-27 04:13:15

GABAA-rho receptor (previously known as the GABAC receptor) is a subclass of GABAA receptors composed entirely of rho (ρ) subunits. GABAA receptors including...

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Tachykinin receptor 1
Senin, 2026-01-05 00:53:03

The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the...

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Co-receptor
Sabtu, 2026-07-18 04:14:54

A co-receptor is a cell surface receptor that binds a signalling molecule in addition to a primary receptor in order to facilitate ligand recognition and...

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Adrenergic receptor autoantibodies
Minggu, 2026-06-14 13:31:28

The adrenergic receptors (or adrenoreceptors) are a class of cell membrane-bound protein receptors throughout the body that are targets of the catecholamines...

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GRK4
Jumat, 2025-08-08 19:41:57

protein-coupled receptor kinase 4 (GRK4) is an enzyme that is encoded by the GRK4 gene in humans. This gene encodes a member of the G protein-coupled receptor kinase...

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Killer activation receptor
Kamis, 2025-10-09 18:49:13

Killer Activation Receptors (KARs) are activating receptors expressed on the plasma membrane (cell membrane) of Natural Killer cells (NK cells). These...

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5-HT4 receptor
Selasa, 2026-02-17 21:35:52

Chamomile (ethanol extract) 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release 89:...

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Interleukin-6 receptor
Selasa, 2025-07-15 14:50:52

Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. Interleukin 6 (IL6) is a potent pleiotropic...

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GABAA receptor positive allosteric modulator
Senin, 2026-08-03 19:21:18

In pharmacology, GABAA receptor positive allosteric modulators, also known as GABAkines or GABAA receptor potentiators, are positive allosteric modulator...

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CCR5 receptor antagonist
Sabtu, 2026-03-28 21:01:43

CCR5 receptor antagonists are a class of small molecules that antagonize the CCR5 receptor. The C-C motif chemokine receptor CCR5 is involved in the process...

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Selective estrogen receptor modulator
Kamis, 2026-06-11 11:43:30

estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), are a class of drugs that act on estrogen receptors (ERs)...

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5-HT1 receptor
Senin, 2026-06-22 21:01:49

The 5-HT1 receptors are a subfamily of the 5-HT serotonin receptors that bind to the endogenous neurotransmitter serotonin (also known as 5-hydroxytryptamine...

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Farnesoid X receptor
Kamis, 2026-06-04 03:01:02

Farnesoid X receptor (FXR), also known as NR1H4 (nuclear receptor subfamily 1, group H, member 4) or bile acid receptor (BAR), is a nuclear receptor that is...

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Asialoglycoprotein receptor
Selasa, 2025-09-23 20:42:12

The asialoglycoprotein receptors (ASGPR) are lectins which bind asialoglycoprotein and glycoproteins from which a sialic acid has been removed to expose...

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Kainate receptor
Rabu, 2025-12-24 11:13:18

Kainate receptors, or kainic acid receptors (KARs), are ionotropic receptors that respond to the neurotransmitter glutamate. They were first identified...

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Adenosine A1 receptor
Minggu, 2026-07-19 07:55:46

A1 receptor (A1AR) is one member of the adenosine receptor group of G protein-coupled receptors with adenosine as endogenous ligand. A1 receptors are...

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LDL receptor
Minggu, 2025-09-28 08:38:22

The low-density lipoprotein receptor (LDL-R) is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) that mediates the endocytosis...

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Vitamin D receptor
Rabu, 2026-05-06 01:02:50

The vitamin D receptor (VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. Calcitriol (the...

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EPH receptor A1
Rabu, 2025-08-06 19:47:24

EPH receptor A1 (ephrin type-A receptor 1) is a protein that in humans is encoded by the EPHA1 gene. This gene belongs to the ephrin receptor subfamily...

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Complement receptor 2
Jumat, 2026-02-13 11:01:07

Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein–Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein...

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Dopamine receptor D3
Minggu, 2026-07-12 22:53:20

Dopamine receptor D3 (DRD3) is a protein belonging to the dopamine receptor family of G protein-coupled receptors. In humans, it is encoded by the DRD3...

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Cutaneous receptor
Sabtu, 2026-02-07 06:10:15

A cutaneous receptor is a sensory receptor found in the skin that provides information about temperature, touch (including vibration and pain), spatial...

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OGFr
Sabtu, 2025-07-19 13:45:31

Opioid growth factor receptor, also known as OGFr or the ζ-opioid receptor, is a protein which in humans is encoded by the OGFR gene. The protein encoded...

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BAFF receptor
Minggu, 2025-09-28 11:38:02

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C) and BLyS receptor...

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Pheromone
Senin, 2026-06-29 08:41:55

lordosis behavior. The human trace amine-associated receptors are a group of six G protein-coupled receptors (i.e., TAAR1, TAAR2, TAAR5, TAAR6, TAAR8, and TAAR9)...

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Neurotensin receptor 2
Kamis, 2026-04-30 06:52:09

receptor type 2 is a protein that in humans is encoded by the NTSR2 gene. The protein encoded by this gene belongs to the G protein-coupled receptor family...

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Testicular receptor 4
Senin, 2026-06-08 09:47:12

Testicular receptor 4 also known as NR2C2 (nuclear receptor subfamily 2, group C, member 2) is a protein that in humans is encoded by the NR2C2 gene. The...

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EPH receptor A4
Sabtu, 2026-02-14 23:19:22

EPH receptor A4 (ephrin type-A receptor 4) is a protein that in humans is encoded by the EPHA4 gene. This gene belongs to the ephrin receptor subfamily...

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CD120
Minggu, 2023-12-03 08:41:50

receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2). There are two variants of the receptor,...

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Histamine receptor
Minggu, 2026-03-29 22:51:16

The histamine receptors are a class of G protein–coupled receptors which bind histamine as their primary endogenous ligand. Histamine is a neurotransmitter...

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CXC chemokine receptors
Selasa, 2024-04-30 14:16:38

CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one...

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5-HT7 receptor
Sabtu, 2026-07-04 06:18:55

The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine...

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Adrenergic agonist
Senin, 2026-06-22 07:04:36

that stimulates a response from the adrenergic receptors. The five main categories of adrenergic receptors are: α1, α2, β1, β2, and β3, although there are...

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D2-like receptor
Kamis, 2025-12-11 08:39:01

The D2-like receptors are a subfamily of dopamine receptors that bind the endogenous neurotransmitter dopamine. The D2-like subfamily consists of three...

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Tachykinin receptor
Senin, 2024-08-12 17:38:34

known mammalian tachykinin receptors termed NK1, NK2 and NK3. All are members of the 7 transmembrane G-protein coupled receptor family and induce the activation...

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Umami
Sabtu, 2026-08-01 21:57:28

characteristic of broths and cooked meats. People taste umami through taste receptors that typically respond to glutamates and nucleotides, which are widely...

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Cytokine receptor
Jumat, 2026-05-22 00:23:42

Cytokine receptors are receptors that bind to cytokines. The binding of cytokines to receptors allows the cell that houses the receptor to be able to receive...

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Locomotor activity
Senin, 2026-04-20 11:43:36

increased. It is induced by certain drugs like psychostimulants and NMDA receptor antagonists and is reversed by certain other drugs like antipsychotics...

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Rhodopsin-like receptors
Senin, 2025-07-14 02:44:17

Rhodopsin-like receptors are a family of proteins that comprise the largest group of G protein-coupled receptors. G-protein-coupled receptors, GPCRs, constitute...

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Leukotriene receptor
Selasa, 2022-05-03 23:40:56

The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins: Leukotriene...

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Pharmacodynamics
Kamis, 2026-06-25 23:45:16

drug-receptor interactions as modeled by L + R ↽ − − ⇀ LR {\displaystyle {\ce {L + R <=> LR}}} where L, R, and LR represent ligand (drug), receptor, and...

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Transferrin receptor 2
Sabtu, 2025-07-19 14:35:35

Transferrin receptor 2 (TfR2) is a protein that in humans is encoded by the TFR2 gene. This protein is involved in the uptake of transferrin-bound iron...

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Cannabinoid receptor modulator
Jumat, 2026-08-07 00:47:21

A cannabinoid receptor modulator is a compound that bind to the cannabinoid receptors, which are receptors in the human body that regulate multiple physiological...

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Nuclear receptor 4A3
Kamis, 2025-12-18 14:33:05

The nuclear receptor 4A3 (NR4A3) (nuclear receptor subfamily 4, group A, member 3) also known as neuron-derived orphan receptor 1 (NOR1) is a protein...

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Buspirone
Jumat, 2026-07-24 07:18:45

mechanism of action involves partial agonism at postsynaptic serotonin 5-HT1A receptors and full agonism at presynaptic 5-HT1A autoreceptors, which initially...

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5-HT2B receptor
Kamis, 2026-08-06 09:13:05

5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene. 5-HT2B is a member...

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5-HT1D receptor
Kamis, 2026-07-30 15:03:17

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it. 5-HT1D acts on the central...

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TGF beta receptor
Minggu, 2025-10-19 03:00:52

Transforming growth factor beta (TGFβ) receptors are single pass serine/threonine kinase receptors that belong to TGFβ receptor family. They exist in several different...

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ACTH receptor
Kamis, 2025-09-25 06:56:51

adrenocorticotropic hormone receptor or ACTH receptor also known as the melanocortin receptor 2 or MC2 receptor is a type of melanocortin receptor (type 2) which is...

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5-HT2 receptor
Jumat, 2022-05-13 07:47:48

subtypes: 5-HT2A receptor 5-HT2B receptor 5-HT2C receptor 5-HT1 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Category:5-HT2...

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Type I cytokine receptor
Sabtu, 2026-01-17 00:32:23

IL-6 receptor IL-11 receptor IL-12 receptor IL-27 receptor Leukemia inhibitory factor receptor Oncostatin M receptor Type I cytokine receptors include...

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GHB receptor
Senin, 2026-07-27 17:24:05

The γ-hydroxybutyrate (GHB) receptor (GHBR), originally identified as GPR172A, is an excitatory G protein-coupled receptor (GPCR) that binds the neurotransmitter...

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Secretin receptor family
Minggu, 2026-05-10 03:23:36

Secretin receptor family (class B GPCR subfamily) consists of secretin receptors regulated by peptide hormones from the glucagon hormone family. In early...

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Membrane corticosteroid receptor
Kamis, 2022-05-12 06:38:53

Membrane corticosteroid receptor include: Membrane glucocorticoid receptor Membrane mineralocorticoid receptor This set index article includes a list of...

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Calcitonin receptor
Senin, 2025-09-29 14:42:43

The calcitonin receptor (CT) is a G protein-coupled receptor that binds the peptide hormone calcitonin and is involved in maintenance of calcium homeostasis...

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Muscarinic acetylcholine receptor M4
Selasa, 2026-07-14 00:33:23

The muscarinic acetylcholine receptor M4, also known as the cholinergic receptor, muscarinic 4 (CHRM4), is a protein that, in humans, is encoded by the...

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Interleukin 20 receptor, alpha subunit
Sabtu, 2025-09-20 02:14:40

Interleukin 20 receptor, alpha subunit, is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the interleukin-24 receptor. The interleukin...

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Cholecystokinin A receptor
Jumat, 2025-08-15 04:11:48

The Cholecystokinin A receptor is a human protein, also known as CCKAR or CCK1, with CCK1 now being the IUPHAR-recommended name. This gene encodes a G-protein...

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Interleukin receptor
Rabu, 2026-07-15 02:02:35

receptor Interleukin-5 receptor Interleukin-6 receptor Interleukin-7 receptor Interleukin-9 receptor Interleukin-11 receptor Interleukin-12 receptor Interleukin-13...

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P2Y receptor
Sabtu, 2026-06-13 22:01:16

P2Y receptors are a family of purinergic G protein-coupled receptors, stimulated by nucleotides such as adenosine triphosphate, adenosine diphosphate,...

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HER2
Rabu, 2026-04-29 00:10:21

Receptor tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated...

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Insulin-like growth factor 1 receptor
Minggu, 2025-09-28 09:50:43

insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone...

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Angiopoietin receptor
Selasa, 2025-09-30 10:20:16

The angiopoietin receptors are receptors that bind angiopoietin. TIE-1 and TIE-2 comprise the cell-surface receptors that bind and are activated by the...

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5-HT3 antagonist
Senin, 2026-04-27 01:49:40

"setrons", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve...

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Netrin receptor DCC
Senin, 2026-06-29 04:07:20

Netrin receptor DCC, also known as DCC, or colorectal cancer suppressor is a protein which in humans is encoded by the DCC gene. DCC has long been implicated...

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Somatostatin receptor 2
Senin, 2026-07-13 10:43:16

Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene. The SSTR2 gene is located on chromosome 17 on the long arm in position...

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List of investigational sex-hormonal agents
Kamis, 2026-06-04 08:21:46

androgen receptor modulator for Duchenne muscular dystrophy Enobosarm (ostarine; GTx-024, MK-2866; S-22; VERU-024) – selective androgen receptor modulator...

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Follicle-stimulating hormone receptor
Kamis, 2025-10-02 05:06:57

The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH)...

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Decoy receptor 3
Sabtu, 2025-07-19 12:35:05

Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor...

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Histamine H3 receptor
Senin, 2026-08-03 01:36:03

Histamine H3 receptors are expressed in the central nervous system and to a lesser extent the peripheral nervous system, where they act as autoreceptors...

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Alpha blocker
Jumat, 2026-01-09 11:33:15

class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). Historically, alpha-blockers were used as a tool for...

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CXCR5
Rabu, 2025-12-03 07:15:07

C-X-C chemokine receptor type 5 (CXC-R5) also known as CD185 (cluster of differentiation 185) or Burkitt lymphoma receptor 1 (BLR1) is a G protein-coupled...

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Melatonin receptor
Jumat, 2026-06-26 01:05:24

Melatonin receptors are G protein-coupled receptors (GPCR) which bind melatonin. Three types of melatonin receptors have been cloned. The MT1 (or Mel1A...

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Antiandrogen
Minggu, 2026-05-03 00:36:52

their biological effects in the body. They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen production. They can be...

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MAS1 oncogene
Minggu, 2024-03-10 14:54:17

oncogene (MAS receptor) is a G protein-coupled receptor which binds the angiotensin II metabolite angiotensin (1-7). The MAS1 receptor, when activated...

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Ryanodine receptor 1
Jumat, 2025-10-03 15:37:13

Ryanodine receptor 1 (RYR-1) also known as skeletal muscle calcium release channel or skeletal muscle-type ryanodine receptor is one of a class of ryanodine...

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Leukotriene B4 receptor
Selasa, 2026-05-05 18:57:42

B4 receptors (BLTRs) include the following two receptors: Leukotriene B4 receptor 1 (BLTR1) Leukotriene B4 receptor 2 (BLTR2) Eicosanoid receptor Leukotriene...

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H2 receptor antagonist
Minggu, 2025-12-21 05:47:04

of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach. This decreases the production of...

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Fibroblast growth factor receptor
Kamis, 2025-10-16 10:01:01

The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...

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Progesterone receptor A
Jumat, 2025-11-14 05:09:25

The progesterone receptor A (PR-A) is one of three known isoforms of the progesterone receptor (PR), the main biological target of the endogenous progestogen...

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EPH receptor B4
Rabu, 2025-08-06 19:56:49

Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental...

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H3 receptor antagonist
Selasa, 2025-10-07 15:57:07

An H3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H3 receptors. Unlike the H1 and H2 receptors which...

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Interleukin-15 receptor
Selasa, 2026-06-23 08:07:01

Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. The IL-15 receptor is composed of the IL-2Rβ and γc subunits, along with...

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Growth hormone receptor
Rabu, 2026-03-25 19:59:41

acids. The receptor is part of the Type I cytokine receptor family of receptors. GHR exists in two forms as a full length membrane-bound receptor and as a...

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Apelin receptor
Selasa, 2026-07-28 11:02:04

The Apelin Receptor is a G protein-coupled receptor which in humans is encoded by the gene APLNR (and also known as APJ). The structure of APLNR was resolved...

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EPH receptor A2
Sabtu, 2026-02-14 01:51:36

EPH receptor A2 (ephrin type-A receptor 2) is a protein that in humans is encoded by the EPHA2 gene. This gene belongs to the ephrin receptor subfamily...

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Ecdysone receptor
Jumat, 2026-01-30 12:41:46

The ecdysone receptor is a nuclear receptor found in arthropods, where it controls development and contributes to other processes such as reproduction...

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Peroxisome proliferator-activated receptor alpha
Kamis, 2026-07-16 19:24:39

proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning...

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C3a receptor
Rabu, 2026-02-11 00:33:19

The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system. The...

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Metabotropic receptor
Selasa, 2026-06-23 10:07:24

A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic...

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Vasopressin receptor 1A
Sabtu, 2025-10-04 17:39:44

Vasopressin receptor 1A (V1AR), or arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for vasopressin...

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5-HT5A receptor
Jumat, 2026-06-12 14:18:58

affinity. SB-699,551 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release 89:...

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Type II cytokine receptor
Kamis, 2026-07-23 21:05:24

Type II cytokine receptors, also commonly known as class II cytokine receptors, are transmembrane proteins that are expressed on the surface of certain...

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EPH receptor B1
Sabtu, 2025-10-18 13:49:05

Ephrin type-B receptor 1 is a protein that in humans is encoded by the EPHB1 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental...

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Oncostatin M receptor
Jumat, 2026-05-01 22:29:05

Oncostatin-M specific receptor subunit beta also known as the Oncostatin M receptor (OSMR), is one of the receptor proteins for oncostatin M, that in humans...

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Estrogen-related receptor
Minggu, 2023-12-03 20:05:05

The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because...

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Receptor protein serine/threonine kinase
Selasa, 2026-01-20 10:30:22

Receptor protein serine/threonine kinases (EC 2.7.11.30) are enzyme-linked receptors that belong to protein-serine/threonine kinases. The systematic name...

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EPH receptor B2
Rabu, 2025-07-16 04:40:05

Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental...

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Receptor potential
Minggu, 2026-05-17 01:13:05

A receptor potential, also known as a generator potential, a type of graded potential, is the transmembrane potential difference produced by activation...

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GRK6
Jumat, 2025-08-08 19:48:43

protein-coupled receptors to regulate their signaling. G protein-coupled receptor kinases phosphorylate activated G protein-coupled receptors, which promotes...

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5-HT2C receptor agonist
Kamis, 2026-04-02 07:07:00

5-HT2C receptor agonists are a class of drugs that activate 5-HT2C receptors. They have been investigated for the treatment of a number of conditions...

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Suvorexant
Jumat, 2026-06-26 11:50:48

Suvorexant is a dual orexin receptor antagonist (DORA). It acts as a selective dual antagonist of the orexin OX1 and OX2 receptors. The medication has an intermediate...

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Prostaglandin D2 receptor
Selasa, 2025-12-09 02:49:11

prostaglandin D2 (PGD2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin D2. Also known as PTGDR or DP receptors, they are important...

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Ryanodine receptor 2
Senin, 2025-08-11 12:51:27

Ryanodine receptor 2 (RYR2) is one of a class of ryanodine receptors and a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2...

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Macrophage mannose receptor 1
Kamis, 2026-07-23 03:23:30

Macrophage mannose receptor 1, also known as mannose receptor C-type 1, is a protein that in humans is encoded by the MRC1 gene. The recognition of complex...

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Vasopressin receptor antagonist
Kamis, 2025-06-19 08:40:50

A vasopressin receptor antagonist (VRA) is an agent that interferes with action at the vasopressin receptors. Most commonly VRAs are used in the treatment...

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Prostaglandin DP1 receptor
Jumat, 2026-05-15 20:10:46

prostaglandin D2 receptor 1 (DP1), a G protein-coupled receptor encoded by the PTGDR gene (also termed PTGDR1), is primarily a receptor for prostaglandin...

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Prostaglandin receptor
Minggu, 2023-05-14 19:45:40

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one...

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Ionotropic glutamate receptor
Sabtu, 2026-04-11 21:51:59

and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors (see below). AMPA receptors are the main charge carriers...

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Vasopressin receptor
Jumat, 2026-07-10 16:10:53

G protein-coupled receptors (GPCRs) called vasopressin receptors that are classified into the V1 (V1A), V2, and V3 (V1B) receptor subtypes. These three...

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Polymeric immunoglobulin receptor
Sabtu, 2026-08-08 10:22:14

Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the PIGR gene. It is an Fc receptor which facilitates the...

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OR6A2
Senin, 2026-07-20 19:18:48

Olfactory receptor 6A2 is a protein that in humans is encoded by the OR6A2 gene. It is Class II (tetrapod-specific) olfactory receptor and a rhodopsin-like...

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Alpha-1A adrenergic receptor
Selasa, 2025-12-30 00:24:55

adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and...

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Prokineticin receptor
Minggu, 2024-03-10 09:51:09

The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different...

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Interleukin-8 receptor
Minggu, 2025-06-22 06:01:33

The interleukin-8 receptors (IL-8R) are two 7-transmembrane proteins in the G-protein coupled-receptor family: interleukin-8 receptor A (IL-8RA) and interleukin-8...

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GFRA2
Rabu, 2026-07-08 22:16:37

GDNF family receptor alpha-2 (GFRα2), also known as the neurturin receptor, is a protein that in humans is encoded by the GFRA2 gene. The GFRA2 protein...

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EF-Tu receptor
Sabtu, 2026-06-20 03:50:51

EF-Tu receptor, abbreviated as EFR, is a pattern-recognition receptor (PRR) that binds to the prokaryotic protein EF-Tu (elongation factor thermo unstable)...

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Glucagon receptor family
Rabu, 2024-01-17 17:09:22

glucagon receptor family is a group of closely related G-protein coupled receptors which include: Glucagon receptor Glucagon-like peptide 1 receptor Glucagon-like...

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Atrial natriuretic peptide receptor
Senin, 2022-03-14 11:28:04

An atrial natriuretic peptide receptor is a receptor for atrial natriuretic peptide. NPRA and NPRB are linked to guanylyl cyclases, while NPRC is G-protein-linked...

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Estrogen receptor beta
Selasa, 2026-07-21 11:01:32

Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear...

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Head-twitch response
Senin, 2026-08-03 14:32:53

drugs besides serotonin 5-HT2A receptor agonists, such as NMDA receptor antagonists and muscarinic acetylcholine receptor antagonists, also induce the HTR...

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Lipoprotein receptor-related protein
Minggu, 2026-08-02 16:05:05

Lipoprotein receptor-related proteins, low-density lipoprotein receptor-related proteins (HGNC), or pro-low-density lipoprotein receptor-related protein...

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Thromboxane receptor
Selasa, 2025-10-21 23:22:12

thromboxane receptor (TP) also known as the prostanoid TP receptor is a protein that in humans is encoded by the TBXA2R gene, The thromboxane receptor is one...

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Cholecystokinin receptor
Minggu, 2025-10-05 10:45:13

Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors which bind the peptide hormones cholecystokinin (CCK) and gastrin...

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NMDA receptor modulator
Minggu, 2026-02-08 03:05:21

NMDA receptor modulators (glutamate modulators) are a new form of antipsychotic that are in Phase II FDA studies. The first compound studied was glycine...

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Interleukin-7 receptor
Sabtu, 2025-07-19 13:10:28

consists of two subunits, interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various cytokines...

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Nociceptin receptor
Sabtu, 2026-06-20 15:00:59

nociceptin opioid peptide receptor (NOP), also known as the nociceptin/orphanin FQ (N/OFQ) receptor or kappa-type 3 opioid receptor, is a protein that in...

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Mincle receptor
Selasa, 2025-09-30 16:08:12

lectin receptor, (abbreviated to Mincle), is a member of the C-type lectin superfamily encoded by the gene CLEC4E. It is a pattern recognition receptor that...

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Prostaglandin E2 receptor
Selasa, 2025-11-04 23:44:17

(PGE2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin E2. They are members of the prostaglandin receptors class...

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TNF receptor superfamily
Jumat, 2026-06-19 00:43:00

The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis...

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Aryl hydrocarbon receptor
Senin, 2026-05-04 12:06:34

The aryl hydrocarbon receptor (also known as AhR, AHR, ahr, ahR, AH receptor, or as the dioxin receptor) is a protein that in humans is encoded by the...

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Liver X receptor
Kamis, 2026-06-04 02:45:34

The liver X receptor (LXR) is a member of the nuclear receptor family of transcription factors and is closely related to nuclear receptors such as the...

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Ciliary neurotrophic factor receptor
Jumat, 2023-12-01 07:52:17

The ciliary neurotrophic factor receptor, also known as CNTFR, binds the ciliary neurotrophic factor. This receptor and its cognate ligand support the...

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Stretch receptor
Sabtu, 2025-09-27 08:51:54

Stretch receptors are mechanoreceptors responsive to distention of various organs and muscles, and are neurologically linked to the medulla in the brain...

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Interleukin 6
Selasa, 2026-08-04 23:19:15

the innate immune system, called pattern recognition receptors (PRRs), including Toll-like receptors (TLRs). These are present on the cell surface and intracellular...

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Adiponectin receptor 2
Minggu, 2025-10-26 17:08:57

Adiponectin receptor 2 (AdipoR2) is a protein which in humans is encoded by the ADIPOR2 gene. It is a member of the progestin and adipoQ receptor (PAQR) family...

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Toll-like receptor 7
Sabtu, 2026-07-04 07:15:21

Toll-like receptor 7, also known as TLR7, is a protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. It is a member...

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H1 antagonist
Rabu, 2026-07-15 01:30:56

receptor, helping to relieve allergic reactions. Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are...

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Prostacyclin receptor
Jumat, 2026-05-01 10:03:29

prostacyclin receptor, also termed the prostaglandin I2 receptor or just IP, is a receptor belonging to the prostaglandin (PG) group of receptors. IP binds...

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LRP1
Sabtu, 2026-08-08 00:32:15

density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster...

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Interleukin 13 receptor, alpha 1
Jumat, 2025-07-18 00:00:35

the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves...

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Pregnane X receptor
Jumat, 2025-10-31 12:50:16

biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I...

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Thermoreceptor
Selasa, 2026-06-23 15:55:50

A thermoreceptor is a non-specialised sense receptor, or more accurately the receptive portion of a sensory neuron, that codes absolute and relative changes...

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Orphan receptor
Jumat, 2026-05-29 23:54:27

In biochemistry, an orphan receptor is a protein that is structurally similar to a receptor, but for which no physiological relevant endogenous ligand...

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Interleukin-1 receptor family
Kamis, 2025-05-22 20:34:40

interleukin-1 receptor (IL-1R) family are characterized by extracellular immunoglobulin-like domains and intracellular Toll/Interleukin-1 receptor/Resistance...

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Tropomyosin receptor kinase A
Senin, 2026-06-15 10:03:39

Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...

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Interleukin-9 receptor
Minggu, 2026-06-14 20:47:17

Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also denotes its human gene. The...

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Γ-Hydroxybutyric acid
Jumat, 2026-07-31 03:06:41

glycine in certain brain areas. It acts on the GHB receptor and is a weak agonist at the GABAB receptor. GHB has been used in medicine as a general anesthetic...

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Brain-derived neurotrophic factor
Jumat, 2026-05-15 22:03:59

Yves-Alain Barde and Hans Thoenen. BDNF activates the TrkB tyrosine kinase receptor. BDNF acts on certain neurons of the central nervous system and the peripheral...

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Selective progesterone receptor modulator
Selasa, 2026-01-13 18:18:28

A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor (PR), the biological target of progestogens like...

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Steroid hormone receptor
Senin, 2026-05-18 13:28:34

hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells. They are generally intracellular receptors (typically...

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Alpha-v beta-3
Selasa, 2025-09-30 17:56:44

αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed...

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Interleukin 15 receptor, alpha subunit
Minggu, 2023-12-24 10:38:12

Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. The IL-15 receptor is composed...

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IL-2 receptor
Minggu, 2025-12-21 00:11:51

The interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds...

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Adenosine A2B receptor
Rabu, 2026-08-05 16:12:12

adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human adenosine A2b receptor gene which encodes...

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Purinergic receptor
Kamis, 2025-10-02 12:47:50

Purinergic receptors, also known as purinoceptors, are a family of plasma membrane molecules that are found in almost all mammalian tissues. Within the...

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Parasympathomimetic drug
Selasa, 2026-06-23 02:22:43

parasympathomimetic drug, sometimes called a cholinomimetic drug or cholinergic receptor stimulating agent, is a substance that stimulates the parasympathetic nervous...

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Peroxisome proliferator-activated receptor gamma
Senin, 2026-05-18 17:06:12

proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1...

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Antiestrogen
Senin, 2025-11-10 08:10:56

their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production. Antiestrogens...

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Alpha-4 beta-2 nicotinic receptor
Sabtu, 2026-07-04 03:01:59

The alpha-4 beta-2 nicotinic receptor, also known as the α4β2 receptor, is a type of nicotinic acetylcholine receptor implicated in learning, consisting...

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Membrane steroid receptor
Senin, 2025-10-20 08:33:23

Membrane steroid receptors (mSRs), also called extranuclear steroid receptors, are a class of cell surface receptors activated by endogenous steroids...

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Selective receptor modulator
Rabu, 2025-03-26 04:17:41

In the field of pharmacology, a selective receptor modulator or SRM is a type of drug that has different effects in different tissues. An SRM may behave...

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Asialoglycoprotein receptor 1
Rabu, 2026-01-07 11:07:49

Asialoglycoprotein receptor 1 is a protein that in humans is encoded by the ASGR1 gene. This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is...

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Adiponectin receptor 1
Selasa, 2026-02-17 10:37:03

Adiponectin receptor 1 (AdipoR1) is a protein which in humans is encoded by the ADIPOR1 gene. It is a member of the progestin and adipoQ receptor (PAQR) family...

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Alpha-3 beta-4 nicotinic receptor
Senin, 2026-07-06 12:57:02

nicotinic receptor, also known as the α3β4 receptor and the ganglion-type nicotinic receptor, is a type of nicotinic acetylcholine receptor, consisting...

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List of investigational antipsychotics
Rabu, 2026-08-05 09:39:07

(mdc-TJK; TEV-749; TV-44749) – dopamine D1 receptor antagonist, dopamine D2 receptor antagonist, serotonin 5-HT2A receptor antagonist, and other actions – schizophrenia...

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Signal transduction
Minggu, 2026-06-14 20:31:39

generally termed receptors, although in some cases the term sensor is used. The changes elicited by ligand binding (or signal sensing) in a receptor give rise...

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Somatostatin receptor 3
Sabtu, 2026-07-04 00:20:51

Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene. Somatostatin acts at many sites to inhibit the release of many hormones...

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Nicotinic agonist
Senin, 2026-07-06 09:47:27

that mimics the action of acetylcholine (ACh) at nicotinic acetylcholine receptors (nAChRs). The nAChR is named for its affinity for nicotine. Examples include...

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Bradykinin receptor B2
Senin, 2026-05-11 11:27:44

Bradykinin receptor B2 is a G-protein coupled receptor for bradykinin, encoded by the BDKRB2 gene in humans. The B2 receptor (B2R) is a G protein-coupled...

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Interleukin-3 receptor
Minggu, 2024-09-08 22:30:33

coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. The receptor belongs to the type I cytokine receptor family and...

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Motilin receptor
Jumat, 2025-06-20 07:36:03

Motilin receptor is a G protein-coupled receptor (previously GPCR38) that binds motilin. It was first cloned in 1999 by Merck Laboratories. and scientists...

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Interleukin-13 receptor
Rabu, 2025-10-22 09:10:07

The interleukin-13 receptor is a type I cytokine receptor, binding Interleukin-13. It consists of two subunits, encoded by IL13RA1 and IL4R, respectively...

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Nerve growth factor
Jumat, 2026-02-27 02:20:50

TrkA receptor facilitates receptor dimerization and tyrosine residue phosphorylation of the cytoplasmic tail by adjacent Trk receptors. Trk receptor phosphorylation...

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Galanin receptor
Selasa, 2026-03-24 20:41:13

The galanin receptor is a G protein-coupled receptor, or metabotropic receptor which binds galanin. Galanin receptors can be found throughout the peripheral...

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Interleukin-1 receptor antagonist
Senin, 2026-01-26 12:38:22

The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. IL-1RA was initially called the IL-1 inhibitor...

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Calcitonin gene-related peptide
Rabu, 2026-07-08 15:03:54

of the receptor. The CGRP receptor has three subunits: receptor activity-modifying protein 1 (RAMP1), calcitonin-like receptor (CLR) and receptor component...

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Extrasynaptic NMDA receptor
Jumat, 2026-08-07 01:26:23

colleagues uncovered that extrasynaptic NMDA receptors form a signaling complex with the transient receptor potential cation channel subfamily M member...

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Daridorexant
Senin, 2026-08-03 11:59:42

The medication is a dual orexin receptor antagonist (DORA). It acts as a selective dual antagonist of the orexin receptors OX1 and OX2. Compared to other...

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Prokineticin receptor 2
Sabtu, 2025-07-19 14:01:45

Prokineticin receptor 2 (PKR2), is a dimeric G protein-coupled receptor encoded by the PROKR2 gene in humans. Prokineticins are secreted proteins that...

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Dopamine receptor D5
Rabu, 2025-09-24 02:09:06

D1-like receptor family along with the D1 receptor subtype. D5 receptor is a subtype of the dopamine receptor that has a 10-fold higher affinity for dopamine...

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Cholecystokinin antagonist
Jumat, 2025-07-25 03:01:56

A cholecystokinin receptor antagonist is a specific type of receptor antagonist which blocks the receptor sites for the peptide hormone cholecystokinin...

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Reticulon 4 receptor
Sabtu, 2025-07-19 14:09:06

Reticulon 4 receptor (RTN4R) also known as Nogo-66 Receptor (NgR) or Nogo receptor 1 is a protein which in humans is encoded by the RTN4R gene. This gene...

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5-HT1F receptor
Sabtu, 2025-07-19 11:57:59

5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it. 5-n-Butyryloxy-DMT:...

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Interleukin-5 receptor
Jumat, 2025-03-14 00:57:49

interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and CSF2RB. The IL-5 receptor (IL-5R)...

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Interleukin 5 receptor alpha subunit
Jumat, 2025-07-18 00:00:46

Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA also denotes...

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Interleukin-4 receptor
Sabtu, 2025-07-19 13:10:26

The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα...

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C5a receptor
Jumat, 2026-07-31 23:33:04

The C5a receptor also known as complement component 5a receptor 1 (C5AR1) or CD88 (Cluster of Differentiation 88) is a G protein-coupled receptor for C5a...

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Interleukin-23 receptor
Jumat, 2025-07-18 00:00:41

interleukin-23 receptor is a type I cytokine receptor. It is encoded in human by the IL23R gene. In complex with the interleukin-12 receptor β1 subunit (IL-12Rβ1)...

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Lymphocyte homing receptor
Rabu, 2025-05-07 07:18:11

Lymphocyte homing receptors are cell adhesion molecules expressed on lymphocyte cell membranes that recognize addressins on target tissues. Lymphocyte...

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Neurotensin receptor 1
Senin, 2026-05-25 04:32:58

Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene. The neurotensin receptor is primarily responsible for mediating the...

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Antileukotriene
Sabtu, 2026-01-17 18:22:25

receptor antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist...

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Prostaglandin EP2 receptor
Kamis, 2025-10-02 08:22:37

Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of...

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TRPP
Sabtu, 2024-12-21 05:18:12

TRPP (transient receptor potential polycystic) is a family of transient receptor potential ion channels which when mutated can cause polycystic kidney...

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P2RX7
Kamis, 2025-10-02 06:15:36

The P2X7 receptor also serves as a pattern recognition receptor for extracellular ATP-mediated apoptotic cell death, regulation of receptor trafficking...

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Prostaglandin F receptor
Selasa, 2025-06-10 00:42:37

Prostaglandin F receptor (FP) is a receptor belonging to the prostaglandin (PG) group of receptors. FP binds to and mediates the biological actions of...

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Interleukin-1 receptor
Rabu, 2025-05-28 01:12:04

Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I receptor is primarily responsible...

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Serotonin receptor antagonist
Rabu, 2026-08-05 05:25:18

or serotonin receptor antagonist, is a drug used to inhibit the action of serotonin and serotonergic drugs at serotonin (5-HT) receptors. Antagonists...

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N-Methyl-D-aspartic acid
Minggu, 2026-07-26 20:00:04

specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA...

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Sensory neuron
Selasa, 2026-05-26 07:59:05

which convert a specific type of stimulus, via their receptors, into action potentials or graded receptor potentials. This process is called sensory transduction...

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Alpha-2B adrenergic receptor
Selasa, 2026-08-04 11:57:48

The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor. It is a subtype of the adrenergic receptor family. The human gene...

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G protein-coupled receptor kinase 2
Jumat, 2025-08-01 20:44:07

G-protein-coupled receptor kinase 2 (GRK2) is an enzyme that in humans is encoded by the ADRBK1 gene. GRK2 was initially called Beta-adrenergic receptor kinase (βARK...

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Interferon-lambda receptor
Jumat, 2026-06-05 13:19:01

Interferon-lambda receptor (IFNLR), formerly known as the interleukin-28 receptor (IL28R), is a type II cytokine receptor found largely in epithelial...

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Renin–angiotensin system
Kamis, 2025-12-11 14:36:17

to receptors on intraglomerular mesangial cells, causing these cells to contract along with the blood vessels surrounding them; and to receptors on the...

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5-HT1E receptor
Sabtu, 2025-07-19 11:57:57

1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor)....

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Renin receptor
Jumat, 2025-07-18 01:08:45

The renin receptor also known as ATPase H(+)-transporting lysosomal accessory protein 2, or the prorenin receptor, is a protein that in humans is encoded...

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Thyroid-stimulating hormone
Jumat, 2026-05-22 11:01:13

TSH, and therefore determines its receptor specificity. The β chain has a 118-amino acid sequence. The TSH receptor is found mainly on thyroid follicular...

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Bradykinin receptor B1
Rabu, 2025-07-16 23:42:56

Bradykinin receptor B1 (B1) is a G-protein coupled receptor encoded by the BDKRB1 gene in humans. Its principal ligand is bradykinin, a 9 amino acid peptide...

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EPH receptor A5
Rabu, 2025-07-16 04:40:03

EPH receptor A5 (ephrin type-A receptor 5) is a protein that in humans is encoded by the EPHA5 gene. This gene belongs to the ephrin receptor subfamily...

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Somatostatin receptor
Senin, 2026-08-03 11:25:44

Somatostatin receptors are receptors for somatostatin, a small neuropeptide associated with inhibitory signaling in wide range of tissues, including the...

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Sense
Sabtu, 2026-07-11 18:32:33

information to and from the brain and body), the different types of sensory receptor cells (such as mechanoreceptors, photoreceptors, chemoreceptors, thermoreceptors)...

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Cannabinoid receptor antagonist
Minggu, 2025-11-30 15:58:00

A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds...

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Estrogen-related receptor gamma
Jumat, 2025-11-14 03:07:47

Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3), is a nuclear receptor that in humans...

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Endocannabinoid system
Sabtu, 2026-06-27 11:21:12

endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central nervous...

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Lysophospholipid receptor
Rabu, 2025-05-28 14:56:09

The lysophospholipid receptor (LPL-R) group are members of the G protein-coupled receptor family of integral membrane proteins that are important for lipid...

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GFRA3
Kamis, 2025-07-17 23:42:10

GDNF family receptor alpha-3 (GFRα3), also known as the artemin receptor, is a protein that in humans is encoded by the GFRA3 gene. The protein encoded...

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Calcitonin gene-related peptide receptor antagonist
Kamis, 2026-07-02 12:17:13

(CGRP) receptor antagonists, commonly known as gepants, are a class of drugs that act as antagonists of the calcitonin gene-related peptide receptor (CGRPR)...

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Transferrin receptor 1
Selasa, 2025-07-15 14:34:29

Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. TfR1...

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Low-affinity nerve growth factor receptor
Minggu, 2025-11-23 22:22:02

The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR...

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Prostaglandin EP3 receptor
Minggu, 2026-06-28 01:35:55

Prostaglandin EP3 receptor (EP3, 53kDa), is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; it is one of four identified...

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Thyrotropin receptor
Kamis, 2023-11-09 08:15:11

The thyrotropin receptor (or TSH receptor) is a receptor (and associated protein) that responds to thyroid-stimulating hormone (also known as "thyrotropin")...

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Muscarinic acetylcholine receptor M5
Selasa, 2025-10-21 03:24:10

human muscarinic acetylcholine receptor M5, encoded by the CHRM5 gene, is a member of the G protein-coupled receptor superfamily of integral membrane...

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Neurotensin receptor
Sabtu, 2026-08-08 00:51:53

Neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the NTSR1 and NTSR2 genes...

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Candesartan
Senin, 2026-06-08 05:48:07

Candesartan is an angiotensin receptor blocker (ARB) primarily used to treat high blood pressure and congestive heart failure. It is always administered...

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Trace amine-associated receptor
Senin, 2026-07-13 10:15:44

amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a family of G protein-coupled receptors that were discovered...

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Activin receptor
Rabu, 2023-03-22 17:58:51

An Activin receptor is a receptor which binds activin. These proteins are receptor-type kinases of Ser/Thr type, which have a single transmembrane domain...

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Dextromethorphan/bupropion
Senin, 2026-07-13 10:55:10

metoprolol, and tamoxifen. Dextromethorphan acts as an NMDA receptor antagonist, σ1 receptor agonist, and serotonin–norepinephrine reuptake inhibitor, among...

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N-Acetylglucosamine receptor
Minggu, 2022-04-17 10:40:44

The N-Acetylglucosamine receptor is a receptor which binds N-Acetylglucosamine. The N-Acetylglucosamine (GlcNAc) receptor has been recently found to interact...

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Cyclobenzaprine
Minggu, 2026-08-09 21:24:25

block serotonin, adrenergic, histamine, and muscarinic acetylcholine receptors. Chemically, it is very similar to tricyclic antidepressants like amitriptyline...

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Retinoid X receptor
Kamis, 2026-07-16 21:56:29

The retinoid X receptor (RXR) is an important family of transcription factors that can combine with various nuclear receptors to form a protein dimer,...

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Melanocortin receptor
Jumat, 2025-03-14 19:16:45

Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. There are five known members of the melanocortin...

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Oxytocin receptor agonist
Senin, 2026-07-27 10:21:02

An oxytocin receptor agonist is a compound that acts as an agonist of the oxytocin receptor. They include peptides like oxytocin and carbetocin and small-molecules...

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NK1 receptor antagonist
Selasa, 2025-11-11 01:48:51

antagonists to prevent nausea and vomiting. The discovery of neurokinin 1 (NK1) receptor antagonists was a turning point in the prevention of nausea and vomiting...

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Opioid modulator
Senin, 2023-04-17 18:00:28

modulator (or opioid receptor modulator) is a drug which has mixed agonist and antagonist actions at different opioid receptors and thus cannot clearly...

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AMPA receptor positive allosteric modulator
Selasa, 2025-12-23 11:54:16

AMPA receptor positive allosteric modulators are positive allosteric modulators (PAMs) of the AMPA receptor (AMPR), a type of ionotropic glutamate receptor...

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Cys-loop receptor
Jumat, 2026-06-12 11:51:57

acetylcholine, GABAA, GABAA-ρ, glycine, 5-HT3, and zinc-activated (ZAC) receptors. These receptors are composed of five protein subunits which form a pentameric...

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Angiopoietin-1 receptor
Selasa, 2026-07-21 03:53:04

Angiopoietin-1 receptor is an angiopoietin receptor protein that in humans is encoded by the TEK gene. TEK is also known as TEK tyrosine kinase, TIE2 and...

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Interleukin 20 receptor, beta subunit
Selasa, 2025-10-14 05:44:21

Interleukin 20 receptor, beta subunit (IL20R2 or IL20RB) is a subunit of the interleukin-20 receptor and interleukin-22 receptor. It is believed to be...

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Prostaglandin EP4 receptor
Senin, 2026-01-26 09:50:16

Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans. It is one of four identified...

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Odapipam
Kamis, 2026-06-04 09:28:58

D1 receptor (Ki = 0.17 nM) over the dopamine D2 receptor (Ki = 942 nM). Its affinities for other dopamine receptors, such as the dopamine D5 receptor, were...

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Anabolic steroid
Jumat, 2026-08-07 14:28:32

the androgen receptor (AR). The term "anabolic steroid" is essentially synonymous with "steroidal androgen" or "steroidal androgen receptor agonist". Anabolic...

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Peroxisome proliferator-activated receptor delta
Sabtu, 2026-08-08 20:20:58

proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is...

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Neuropeptide S receptor
Selasa, 2025-11-11 15:06:10

The neuropeptide S receptor (NPSR) is a member of the G-protein coupled receptor superfamily of integral membrane proteins which binds neuropeptide S...

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Neonatal fragment crystallizable receptor
Selasa, 2026-07-28 18:53:47

neonatal fragment crystallizable (Fc) receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded...

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Testicular receptor 2
Senin, 2026-06-15 13:01:15

The testicular receptor 2 (TR2) also known as NR2C1 (nuclear receptor subfamily 2, group C, member 1) is a protein that in humans is encoded by the NR2C1...

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Hill equation (biochemistry)
Senin, 2026-07-27 03:32:58

{\ce {R}}} is the receptor. θ {\displaystyle \theta } can be expressed in terms of the total amount of receptor and ligand-bound receptor concentrations:...

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Interleukin-10 receptor
Jumat, 2024-07-05 22:20:24

Interleukin-10 receptor (IL-10R) is a type II cytokine receptor. The receptor is tetrameric, composed of 2α and 2β subunits. The α subunit (encoded in...

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List of investigational hallucinogens and entactogens
Minggu, 2026-08-09 16:22:30

non-hallucinogenic serotonin 5-HT2A receptor agonists and non-hallucinogenic ketamine analogues. Cannabinoids, or cannabinoid receptor modulators, are not included...

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Adenosine A3 receptor
Rabu, 2026-08-05 16:09:39

adenosine A3 receptor, also known as ADORA3, is an adenosine receptor, but also denotes the human gene encoding it. Adenosine A3 receptors are G protein-coupled...

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GFRA1
Rabu, 2025-07-16 04:44:06

GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor, is a protein that in humans is encoded by the GFRA1 gene. Glial cell line-derived...

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Prostaglandin DP2 receptor
Selasa, 2025-07-15 11:39:27

Prostaglandin D2 receptor 2 (DP2 or CRTH2) is a human protein encoded by the PTGDR2 gene. DP2 has also been designated as CD294 (cluster of differentiation...

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ADCYAP1R1
Senin, 2026-04-13 11:33:02

cyclase-activating polypeptide type I receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene. This receptor binds pituitary adenylate...

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Nicotine
Jumat, 2026-08-07 07:13:04

primarily as a stimulant by binding to and activating nicotinic acetylcholine receptors (nAChRs) in the central nervous system and peripheral tissues. This results...

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Mineralocorticoid receptor
Kamis, 2026-05-07 03:35:23

The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2 (NR3C2) is...

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Interleukin-12 receptor
Rabu, 2025-05-28 06:41:34

Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12 and consisting of beta 1 and beta 2 subunits. Chua AO, Chizzonite R, Desai...

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Amlodipine
Kamis, 2026-07-30 23:41:25

angiotensin II receptor antagonist. Amlodipine/valsartan or amlodipine/valsartan/hydrochlorothiazide, where valsartan is an angiotensin II receptor antagonist...

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Alpha-2C adrenergic receptor
Rabu, 2025-07-16 04:22:14

The alpha-2C adrenergic receptor (α2C adrenoceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding...

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Adenosine A2 receptor
Sabtu, 2026-01-17 04:03:38

subtypes of adenosine A2 receptors are known. Both are G protein-coupled adenosine receptors: Adenosine A2A receptor Adenosine A2B receptor This set index article...

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List of antidepressants
Kamis, 2026-07-09 11:02:49

Metatone) – also a 5-HT2A receptor antagonist Viloxazine (Qelbree, formerly Vivalan) – also a 5-HT2B receptor antagonist and 5-HT2C receptor agonist Atomoxetine...

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Allosteric modulator
Senin, 2026-04-20 11:13:16

allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli. Some of them, like benzodiazepines or...

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CALCRL
Senin, 2026-08-03 12:18:27

Calcitonin receptor-like (CALCRL), also known as the calcitonin receptor-like receptor (CRLR), is a human protein; it is a receptor for calcitonin gene-related...

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Sortilin-related receptor
Minggu, 2026-08-09 11:25:37

receptor (SORLA) is a protein that in humans is encoded by the SORL1 gene. SORLA, is a 2214 residue type I transmembrane protein. SORLA a is receptor...

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Orexin receptor type 2
Sabtu, 2026-06-27 11:06:44

Orexin receptor type 2 (Ox2R or OX2), also known as hypocretin receptor type 2 (HcrtR2), is a protein that in humans is encoded by the HCRTR2 gene. It...

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Propranolol
Senin, 2026-07-27 16:49:01

is a non-selective beta blocker which works by blocking β-adrenergic receptors. Propranolol was patented in 1962 and approved for medical use in 1964...

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Immune receptor
Jumat, 2026-05-15 20:01:27

An immune receptor (or immunologic receptor) is a receptor, usually on a cell membrane, which binds to a ligand (usually another protein, such as cytokine)...

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Interleukin-11 receptor
Sabtu, 2024-11-02 16:00:36

interleukin 11 receptor is a type I cytokine receptor, binding interleukin 11. It is a heterodimer composed of an interleukin 11 receptor alpha subunit...

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CXCR3
Selasa, 2025-11-25 00:18:48

Chemokine receptor CXCR3 is a Gαi protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9)...

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Beta-3 adrenergic receptor
Selasa, 2025-07-29 02:12:19

The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. Actions...

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GABA receptor antagonist
Minggu, 2025-08-24 23:09:36

GABA receptor antagonists are drugs that inhibit the action of GABA. In general these drugs produce stimulant and convulsant effects, and are mainly used...

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Macrophage-1 antigen
Sabtu, 2025-09-27 19:50:21

antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2). The integrin...

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Interleukin-17 receptor
Selasa, 2025-01-21 12:10:20

Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a...

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NPR2
Kamis, 2025-07-17 01:07:10

receptor B (NPR2), also known as atrionatriuretic peptide receptor B and formerly as guanylate cyclase B, is an atrial natriuretic peptide receptor which...

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Interleukin-22 receptor
Selasa, 2026-02-10 06:26:19

Interleukin-22 receptor is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1 and IL-10Rβ2 subunits. Xie MH, Aggarwal...

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Formyl peptide receptor
Minggu, 2026-03-29 21:38:43

peptide receptors (FPR) belong to a class of G protein-coupled receptors involved in chemotaxis. In humans, there are three formyl peptide receptor isoforms...

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Corticosteroid receptor
Selasa, 2026-06-23 01:33:08

The corticosteroid receptors are receptors for corticosteroids. Corticosteroid receptors mediate the target organ response to the major products of the...

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Muscarinic acetylcholine receptor M2
Senin, 2026-06-29 12:18:25

muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded...

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Photoreceptor cell
Jumat, 2026-03-13 10:01:48

cells, depending upon the type of receptor imbedded in that cell's membrane. When glutamate binds to an ionotropic receptor, the bipolar cell will depolarize...

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Interleukin-27 receptor
Selasa, 2025-10-21 23:29:51

interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit and...

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Angiotensin II receptor type 1
Sabtu, 2025-07-19 12:06:00

Angiotensin II receptor type 1 (AT1) is a Gq/11-coupled G protein-coupled receptor (GPCR) and the best characterized angiotensin receptor. It is encoded...

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IL31RA
Kamis, 2025-07-17 23:58:34

Interleukin-31 receptor A is a protein that in humans is encoded by the IL31RA gene. IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor subunit...

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BMY-7378
Rabu, 2025-12-24 12:37:40

BMY-7,378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist. Goetz AS, King HK, Ward SD, True TA, Rimele TJ,...

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Prolactin
Selasa, 2026-06-23 13:46:50

autocrine, and paracrine manners through the prolactin receptor and numerous cytokine receptors. Pituitary prolactin secretion is regulated by endocrine...

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Anti-Müllerian hormone type-2 receptor
Selasa, 2026-07-07 12:04:00

Anti-Muellerian hormone type-2 receptor (AMHR2), also known as Müllerian inhibiting substance type II receptor (MISRII), is a receptor for anti-Müllerian hormone...

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Alprazolam
Rabu, 2026-08-05 01:03:13

receptor site and modulating its function; GABA receptors are the most prolific inhibitory receptor within the brain. The GABA chemical and receptor system...

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Retinoic acid receptor
Sabtu, 2025-12-20 03:14:20

The retinoic acid receptor (RAR) is a type of nuclear receptor which can also act as a ligand-activated transcription factor that is activated by both...

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MDMA
Minggu, 2026-08-09 14:05:04

α2-adrenergic receptors, with the sigma σ1 and σ2 receptors, with the imidazoline I1 receptor, and with other targets. Along with the preceding receptor interactions...

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Retinoic acid receptor gamma
Selasa, 2026-07-21 11:21:10

Retinoic acid receptor gamma (RAR-γ), also known as NR1B3 (nuclear receptor subfamily 1, group B, member 3) is a nuclear receptor encoded by the RARG...

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Nuclear receptor coactivator 2
Senin, 2024-10-28 21:52:05

The nuclear receptor coactivator 2 also known as NCoA-2 is a protein that in humans is encoded by the NCOA2 gene. NCoA-2 is also frequently called glucocorticoid...

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Urotensin-II receptor
Minggu, 2024-03-10 09:58:18

The urotensin-2 receptor (UR-II-R) also known as GPR14 is a class A rhodopsin family G protein coupled-receptor (GPCR) that is 386 amino acids long which...

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CC chemokine receptors
Minggu, 2023-12-03 19:13:49

CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine...

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Endothelin receptor antagonist
Senin, 2026-07-13 10:34:33

An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors. Three main kinds of ERAs exist: Dual ET Receptor Antagonists, which...

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Secretin receptor
Rabu, 2026-05-06 03:40:32

The secretin receptor is a protein that in humans is encoded by the SCTR gene. This protein is a G protein-coupled receptor which binds secretin and is...

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Bradykinin receptor
Kamis, 2023-12-21 18:52:39

Bradykinin receptors: the B1 receptor and the B2 receptor. Bradykinin receptor B1 (B1) is a G-protein coupled receptor encoded by the BDKRB1 gene in...

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Complement receptor 1
Jumat, 2026-03-13 01:04:25

Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1...

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Gastric inhibitory polypeptide receptor
Jumat, 2026-08-07 00:49:41

gastric inhibitory polypeptide receptor (GIP-R), also known as the glucose-dependent insulinotropic polypeptide receptor, is a protein that in humans is...

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Scavenger receptor (endocrinology)
Rabu, 2024-09-25 00:18:37

Scavenger receptors in endocrinology are inactive membrane receptors which bind certain hormones such as IGF-1 and do not transmit an intracellular response...

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Caffeine
Minggu, 2026-08-09 10:35:15

Caffeine acts by blocking the binding of adenosine at a number of adenosine receptor types, inhibiting the centrally depressant effects of adenosine and enhancing...

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Eicosanoid receptor
Kamis, 2025-09-25 05:48:31

Most of the eicosanoid receptors are integral membrane protein G protein-coupled receptors (GPCRs) that bind and respond to eicosanoid signaling molecules...

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IL2RA
Rabu, 2026-02-25 16:33:28

The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2...

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Nuclear receptor coactivator 1
Senin, 2024-10-28 21:43:27

The nuclear receptor coactivator 1 (NCOA1), also called steroid receptor coactivator-1 (SRC-1), is a transcriptional coregulatory protein that contains...

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Agonist-antagonist
Senin, 2026-05-11 12:16:00

activating the receptor that it binds to, it blocks the receptor to a natural agonist. Types of mixed agonist/antagonist include receptor ligands that act...

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KIT gene
Kamis, 2026-07-30 02:09:03

Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation...

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Insect olfactory receptor
Rabu, 2024-06-19 11:06:39

Insect olfactory receptors (also known as odorant receptors, ORs) are expressed in the cell membranes of the olfactory sensory neurons of insects. Similarly...

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Androgen
Sabtu, 2026-06-20 21:37:36

male physiological characteristics in vertebrates by binding to androgen receptors. This includes the embryological development of the primary male sex organs...

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Cyclic AMP receptors
Sabtu, 2021-08-07 22:33:11

Cyclic AMP receptors from slime molds are a distinct family of G-protein coupled receptors. These receptors control development in Dictyostelium discoideum...

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GRK5
Jumat, 2025-08-08 19:46:28

G protein-coupled receptor kinase 5 is a member of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinases, and is most highly...

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Taste
Jumat, 2026-08-07 19:10:00

stimulated when a substance in the mouth reacts chemically with taste receptor cells located on taste buds in the oral cavity, mostly on the tongue. Taste...

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Nuclear receptor 4A1
Rabu, 2026-05-06 11:18:37

The nuclear receptor 4A1 (NR4A1 for "nuclear receptor subfamily 4 group A member 1") also known as Nur77, TR3, and NGFI-B is a protein that in humans...

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GFRA4
Kamis, 2025-07-17 23:42:12

GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene. GFRα GRCh38: Ensembl...

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Endothelin A receptor
Selasa, 2025-07-15 11:07:54

Endothelin receptor type A, also known as ETA, is a human G protein-coupled receptor. Endothelin receptor type A has been shown to interact with HDAC7A...

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Vasopressin receptor 2
Selasa, 2026-06-02 08:51:51

Vasopressin receptor 2 (V2R), or arginine vasopressin receptor 2 (officially called AVPR2), is a protein that acts as receptor for vasopressin. AVPR2 belongs...

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Low-density lipoprotein receptor adapter protein 1
Sabtu, 2025-07-19 13:23:58

Low-density lipoprotein receptor adapter protein 1 is a protein that in humans is encoded by the LDLRAP1 gene. The protein encoded by this gene is a cytosolic...

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