Mannuronate reductase

mannuronate reductase
Identifiers
EC no.1.1.1.131
CAS no.37250-62-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a mannuronate reductase (EC 1.1.1.131) is an enzyme that catalyzes the chemical reaction

D-mannonate + NAD(P)+ D-mannuronate + NAD(P)H + H+

The 3 substrates of this enzyme are D-mannonate, NAD+, and NADP+, whereas its 4 products are D-mannuronate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-mannonate:NAD(P)+ 6-oxidoreductase. Other names in common use include mannonate dehydrogenase, mannonate (nicotinamide adenine dinucleotide, (phosphate))dehydrogenase, mannonate dehydrogenase, mannuronate reductase, mannonate dehydrogenase (NAD(P)+), D-mannonate:nicotinamide adenine dinucleotide (phosphate, and oxidoreductase (D-mannuronate-forming)).

References

  • Farmer JJ, Eagon RG (January 1969). "Aldohexuronic acid catabolism by a soil Aeromonas". Journal of Bacteriology. 97 (1): 97–106. PMC 249554. PMID 4388117.


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