genes have decreased R-loop levels and decreased DNA damage compared to intronless genes of similar expression. Insertion of an intron within an R-loop prone...

determination in therian mammals (placentals and marsupials). SRY is an intronless sex-determining gene on the Y chromosome. Mutations in this gene lead...

later recognized as a calcium signal transducer (TACSTD2/Trop-2). This intronless gene is located at the short arm of chromosome 1 (1p32.1). It encodes...

(WBSCR18), is a protein that in humans is encoded by the DNAJC30 gene. This intronless gene encodes a member of the DNAJ molecular chaperone homology domain-containing...

cellular growth, and differentiation. The specific function of this intronless, retinoic acid-induced gene has not yet been determined; however, it has...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

it is a homopolymer of H type ferritin and appears to have no introns (intronless) in its genetic code. The mitochondrial ferritin's Ramachandran plot shows...

somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. Neuropeptide...

protein 1 is a protein that in humans is encoded by the PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition of a fully...

have been predicted within PRE. PRE 1151–1410 enhances nuclear export of intronless transcripts and represses the splicing mechanism to a comparable degree...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene...

the rest of the animal kingdom in that most of their type I IFNs are intronless, and are placed in a position not colinear with the other vertebrates...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha...

receptor 45 is a protein that in humans is encoded by the GPR45 gene. This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family...

{\displaystyle \rightleftharpoons } L-thyroxine + AH2 The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological...

that in humans is encoded by the FRAT2 gene. The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this...

multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1 intronless gene which has similar functions. This gene and PCBP-1 has paralogues...

is encoded by the INSM1 gene. Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

CNR1 gene is used in animals as a nuclear DNA phylogenetic marker. This intronless gene has first been used to explore the phylogeny of the major groups...

role in T cell proliferation and activation. This gene appears to be intronless and is clustered together with KCNA2 and KCNA10 genes on chromosome 1...

The structure of these non-autonomous elements generally consists of an intronless gene encoding a transposase protein, and may or may not have a promoter...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer...

Saitohin is a protein that in humans is encoded by the STH gene. This intronless gene encodes for 128 amino acids in an open reading frame. It is located...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and...

functions to recruit ALYREF, an RNA export adaptor, to the spliced or intronless mRNA. After transfer of the mRNA from UAP56 to ALYREF, UAP56 dissociates...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. GRCh38: Ensembl release 89:...

expressed in neural and testicular tissues and encoded by an X-linked intronless gene". J. Biol. Chem. 269 (24): 16971–6. doi:10.1016/S0021-9258(19)89484-X...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. ENSG00000273793...

SOX-14 is a protein that in humans is encoded by the SOX14 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription...

GLUD1 has been retro-posed to the X chromosome, where it gave rise to the intronless GLUD2 through random mutations and natural selection. GLUD2 have adapted...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

"HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene". DNA Cell Biol. 20 (5): 257–64. doi:10.1089/104454901750232454....

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. GRCh38: Ensembl release...

receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene...

facilitates the compaction of chromatin into higher-order structures. This intronless gene encodes a member of the histone H1 family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

and residues in the TM-4, TM-5 and TM-6. A human clone containing an intronless open reading frame was found to encode 377 amino acids of the 5HT1D receptor...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone...

Reprimo gene family which consists of two human-related protein-coding and intronless genes: Reprimo (RPRM) and RPRML. Although poorly characterized, this lineage...

homolog (Ru), is a protein that in humans is encoded by the HPS6 gene. This intronless gene encodes a protein that may play a role in organelle biogenesis associated...

human gene encoding the β2 adrenoreceptor is ADRB2. The ADRB2 gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

that in humans is encoded by the LCMT2 gene. The protein encoded by this intronless gene belongs to the methyltransferase superfamily and acts as a G1/S and...

"HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene". DNA Cell Biol. 20 (5): 257–64. doi:10.1089/104454901750232454....

chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation...

CCAAT/Enhancer Binding Proteins see the specific page. The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

(2014-07-18). "DFA7, a New Method to Distinguish between Intron-Containing and Intronless Genes". PLOS ONE. 9 (7) e101363. Bibcode:2014PLoSO...9j1363Y. doi:10.1371/journal...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene...

as A2AB) is used in animals as a nuclear DNA phylogenetic marker. This intronless gene has first been used to explore the phylogeny of the major groups...

taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a testis/sperm-specific member of the histone H2B family....

a protein that in humans is encoded by the NAP1L3 gene. This gene is intronless and encodes a member of the nucleosome assembly protein (NAP) family....

SOX-11 is a protein that in humans is encoded by the SOX11 gene. This intronless gene encodes a member of the group C SOX (SRY-related HMG-box) transcription...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

helicase 53 is a protein that in humans is encoded by the DDX53 gene. This intronless gene encodes a protein which contains several domains found in members...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

(Fz-8) is a protein that in humans is encoded by the FZD8 gene. This intronless gene is a member of the frizzled gene family. Members of this family encode...

Couture-Tosi E (August 1989). "Complement genes C1r and C1s feature an intronless serine protease domain closely related to haptoglobin". Journal of Molecular...

that in humans is encoded by the CEBPD gene. The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain...

(CNO) is a protein that in humans is encoded by the BLOC1S4 gene. This intronless gene encodes a protein that may play a role in organelle biogenesis associated...

the compaction of chromatin into higher order structures. This gene is intronless, and encodes a member of the histone H3 family. Transcripts from this...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene...

1021/bi00068a015. PMID 8485135. Rubtsov IuP, Vartapetian AB (1996). "[New intronless members of human prothymosin alpha genes]". Mol. Biol. (Mosk.). 29 (6):...

evolved a function that is independent of the ribosome. This gene is intronless. GRCh38: Ensembl release 89: ENSG00000165496 – Ensembl, May 2017 GRCm38:...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

that in humans is encoded by the JUND gene. The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the...

factor SOX-4 is a protein that in humans is encoded by the SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription...

Israel Y (September 1990). "Human dopamine D1 receptor encoded by an intronless gene on chromosome 5". Nature. 347 (6288): 80–83. Bibcode:1990Natur.347...

1992). "A human serotonin 1D receptor variant (5HT1D beta) encoded by an intronless gene on chromosome 6". Proceedings of the National Academy of Sciences...

analysis of the promoters of the human CaMIII calmodulin gene and of the intronless gene coding for a calmodulin-like protein". Biochim Biophys Acta. 1163...

(C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption...

gene is located on the long (q) arm of chromosome 9 at position 22 This intronless gene belongs to the forkhead family of transcription factors, which is...

transcript. FOXD4L1. The forkhead box D4-like gene is an example of an intronless gene. The function of this gene is not known, but it may code for a transcription...

Berrettini WH, Ala-Kokko L (2001). "C18orf2, a novel, highly conserved intronless gene within intron 5 of the GNAL gene on chromosome 18p11". Cytogenet...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone...

with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway". J. Virol. 76 (24): 12877–89. doi:10...

Adams JC, Morton CC (Sep 2004). "Isolation from cochlea of a novel human intronless gene with predominant fetal expression". J Assoc Res Otolaryngol. 5 (2):...

that do can enhance expression between 2– and >1,000–fold relative to an intronless control. In Arabidopsis and other plant species, the IMEter has been developed...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

Nava A, Danieli GA (Nov 2000). "Characterization of C14orf4, a novel intronless human gene containing a polyglutamine repeat, mapped to the ARVD1 critical...

lipids. CYP8B1 is unique among the cytochrome P450 genes in that it is intronless. CYP8B1 is an endoplasmic reticulum membrane protein and catalyzes the...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

TAFII55 is a protein that in humans is encoded by the TAF7 gene. The intronless gene for this transcription coactivator is located between the protocadherin...

that in humans is encoded by the CEBPB gene. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain...

which is coded by two exons. The human TAAR1 gene is thought to be an intronless gene. To date, TAAR1 has been identified and cloned in five different...

MDA-5) leads to the rapid induction of type I IFNs due to their (mostly) intronless gene structure. The regulatory elements upstream of type I IFN genes differ...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

eosinophil-derived neurotoxin and eosinophil cationic protein genes: evidence for intronless coding sequences in the ribonuclease gene superfamily". Genomics. 7 (4):...

thereby contributing to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

eosinophil-derived neurotoxin and eosinophil cationic protein genes: evidence for intronless coding sequences in the ribonuclease gene superfamily". Genomics. 7 (4):...

encodes a 66 base pair 5'-untranslated sequence, the second of which has an intronless open reading frame coding for a protein containing ~354 amino acids; the...

cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. Agonists Sphingosine-1-phosphate...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this...

Tiano HF, Li SS (February 1985). "Nucleotide sequences of the cDNA and an intronless pseudogene for human lactate dehydrogenase-A isozyme". European Journal...

that in humans is encoded by the RNF26 gene. The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene...

chloroplast genomes of other algae and plants. Most of its genes are intronless. As is the case with most model organisms, genetic tools have been developed...

the RAP2B gene. RAP2B belongs to the Ras-related protein family. This intronless gene belongs to a family of RAS-related genes. The proteins encoded by...

reverse transcriptase polymerase chain reaction to monitor expression of intronless genes". BioTechniques. 9 (3): 262, 264, 266–8. PMID 1699561. Bryant S...

the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this...

Retroposition. Transcripts may be reverse transcribed and integrated as an intronless gene elsewhere in the genome. This new gene may then undergo divergence...

outputs in the circadian neural circuit. In Drosophila, the pdf gene is intronless and is located at 97B on the third chromosome. It exists in a single copy...

duration of cardiac action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1...

Necdin is a protein that in humans is encoded by the NDN gene. This intronless gene is located in the Prader–Willi syndrome (PWS) deletion region. It is...

the human pyruvate dehydrogenase E1 alpha subunit is coded for by an intronless gene on chromosome 4". Genomics. 8 (2): 225–232. doi:10.1016/0888-7543(90)90275-Y...

repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1...

cubomedusan jellyfish lens constitute a novel family encoded in at least three intronless genes". The Journal of Biological Chemistry. 268 (16): 11894–901. doi:10...

Drysdale J (July 2001). "A human mitochondrial ferritin encoded by an intronless gene". J. Biol. Chem. 276 (27): 24437–40. doi:10.1074/jbc.C100141200....

genecards.org. Retrieved 2021-07-30. Grzybowska EA (July 2012). "Human intronless genes: functional groups, associated diseases, evolution, and mRNA processing...

Neu-Yilik G, Gehring NH, Hentze MW, Kulozik AE (February 2002). "The human intronless melanocortin 4-receptor gene is NMD insensitive". Human Molecular Genetics...

is composed of 352 amino acids and its gene, similar to FPR1, has an intronless open reading frames which encodes a protein with the 7 transmembrane structure...

nucleolus, and nucleoplasm of the cell. RIOX1 is a single-exon-gene, intronless, and is found across several species. The gene is involved in gene transcription...

taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning...

analysis of the promoters of the human CaMIII calmodulin gene and of the intronless gene coding for a calmodulin-like protein". Biochimica et Biophysica Acta...

expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning...

hypertrophy. Human urotensin II receptor is located on chromosome 17q25 as an intronless gene. There are no known subtypes of the receptor but the possibility...

The third proposed mechanism is the direct transfer and integration of intronless mtDNA into the nucleus, where editing and introns in the mitochondrion...

The gene encodes for a 2285 nucleotide mRNA transcript that is intronless. Human intronless genes represent a unique subset of the genome that are often...

1074/jbc.274.38.27168. PMID 10480933. Schimenti JC (2000). "ORFless, intronless, and mutant transcription units in the mouse t complex responder (Tcr)...

migrating crest cells, ganglia, somites and myoepicaridal layer. This intronless gene is deleted in AMME contiguous gene syndrome and is potentially involved...

confining the holoenzyme to discrete locations within the cell. This gene is intronless and encodes a member of the AKAP family. The encoded protein binds to...

human FPR2 gene encodes the 351 amino acid receptor, FPR2, within an intronless open reading frame. It forms a cluster with FPR1 and FPR3 genes on chromosome...

upstream in-frame stop codon is found within the 5' UTR. RNF113A is an intronless gene with one isoform in humans. RNF113A translates a human protein 343...

diseases such as diabetes mellitus type 2 and rheumatoid arthritis. This intronless gene encodes a 70kDa heat shock protein which is a member of the heat...

Cavanagh AC (2001). "The murine chaperonin 10 gene family contains an intronless, putative gene for early pregnancy factor, Cpn10-rs1". Mamm. Genome. 12...

organization of an intron-containing sperm protein 17 gene (Sp17-1) and an intronless pseudogene (Sp17-2) in humans: a new model". Biochim. Biophys. Acta. 1578...

region and the 3′UTR. The coding sequence of the BLCAP gene is therefore intronless. A to I RNA editing is catalyzed by a family of adenosine deaminases acting...

the OR9M1P pseudogene are located downstream. OR5L2 is a single-exon, intronless gene, similar to its OR counterparts, with the entire coding sequence...

PMID 18078822. Friend K, Lovejoy AF, Steitz JA (2007). "U2 snRNP binds intronless histone pre-mRNAs to facilitate U7-snRNP-dependent 3' end formation"....