Fenleuton

Fenleuton
Clinical data
Trade namesLofrin
ATC code
  • none
Identifiers
  • 1-{4-[3-(4-Fluorophenoxy)phenyl]-3-butyn-2-yl}-1-hydroxyurea
CAS Number
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H15FN2O3
Molar mass314.316 g·mol−1
3D model (JSmol)
  • CC(C#Cc1cccc(c1)Oc2ccc(cc2)F)N(C(=O)N)O
  • InChI=InChI=1S/C17H15FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-4,7-12,22H,1H3,(H2,19,21)
  • Key:MWXPQCKCKPYBDR-UHFFFAOYSA-N[1]

Fenleuton (trade name Lofrin) is a drug that acts as a 5-lipoxygenase inhibitor and inhibits leukotriene (LTB4, LTC4, LTD4, and LTE4) formation. It has been studied for potential use in veterinary medicine to treat respiratory diseases such as chronic obstructive pulmonary disease (COPD) in horses.[2]

References

  1. ^ "1-{4-[3-(4-Fluorophenoxy)phenyl]-3-butyn-2-yl}-1-hydroxyurea". chemspider.com. Retrieved 24 December 2015.
  2. ^ Marr KA, Lees P, Page CP, Cunningham FM (1998). "Effect of the 5-lipoxygenase inhibitor, fenleuton, on antigen-induced neutrophil accumulation and lung function changes in horses with chronic obstructive pulmonary disease". J Vet Pharmacol Ther. 21 (3): 241–246. doi:10.1046/j.1365-2885.1998.00127.x. PMID 9673966.


Stub icon

This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.

Read other articles:

Cinderella Man (seri televisi)

Cinderella ManPoster promosi untuk Cinderella ManGenreRomansa DramaDitulis olehJo Yoon-yeongSutradaraYeo Jeong-joonPemeranKwon Sang-wooIm YoonaHan Eun-jungSong Chang-euiNegara asalKorea SelatanBahasa asliKoreaJmlh. episode16ProduksiLokasi produksiKoreaDurasiRabu dan Kamis pukul 21:55Rilis asliJaringanMunhwa Broadcasting CorporationRilis15 April (2009-04-15) –4 Juni 2009 (2009-6-4) Korean nameHangul신데렐라 맨 Alih AksaraSinderella MaenMcCune–ReischauerSinderella Maen ...

 

 

Холокост на Украине

Часть серии статей о Холокосте Идеология и политика Расовая гигиена · Расовый антисемитизм · Нацистская расовая политика · Нюрнбергские расовые законы Шоа Лагеря смерти Белжец · Дахау · Майданек · Малый Тростенец · Маутхаузен ·&...

 

 

Virus

Pour les articles homonymes, voir Virus (homonymie). Virus Modèle scientifique du SARS-Cov-2.Classification ICTV Domaines de rang inférieur Adnaviria Duplodnaviria Monodnaviria Riboviria Ribozyviria Varidnaviria classe Naldaviricetes (et des familles non classées) Un virus est un agent infectieux nécessitant un hôte, souvent une cellule, dont les constituants et le métabolisme déclenchent la réplication. Le nom virus a été emprunté au XVIe siècle par Ambroise Paré[1] au lat...

Kalender Gregorius

2024 dalam kalender lainKalender Gregorian2024MMXXIVKalender Bahá'í180–181Kalender Bali1945–1946Kalender Bengali1431Kalender Berber2974Kalender Buddha2568Kalender Burma1386Kalender Tionghoa癸卯年 (Kelinci Air)4720 atau 2574    — sampai —甲辰年 (Naga Kayu)4721 atau 2575Kalender Koptik1740–1741Kalender Etiopia2016–2017Kalender Ibrani5784–5785Kalender Hindu - Vikram Samvat2080–2081 - Shaka Samvat1946–1947 - Kali Yug...

 

 

1922 Arizona gubernatorial election

For related races, see 1922 United States gubernatorial elections. 1922 Arizona gubernatorial election ← 1920 November 7, 1922 1924 →   Nominee George W. P. Hunt Thomas E. Campbell Party Democratic Republican Popular vote 37,310 30,599 Percentage 54.94% 45.06% County resultsHunt:      50–60%      60–70%Campbell:      50–60% Governor before election Thomas E. Campbell Republican El...

 

 

Voie de communication

« Voie » redirige ici. Pour les autres significations, voir Voie (homonymie). Si ce bandeau n'est plus pertinent, retirez-le. Cliquez ici pour en savoir plus. Cet article ne cite pas suffisamment ses sources (février 2024). Si vous disposez d'ouvrages ou d'articles de référence ou si vous connaissez des sites web de qualité traitant du thème abordé ici, merci de compléter l'article en donnant les références utiles à sa vérifiabilité et en les liant à la section «...

Shafaq Naaz

Shafaq NaazShafaq Naaz 2019Lahir7 Februari 1992 (umur 32)Tempat tinggalMumbai, Maharashtra, India Shafaq Naaz adalah aktris dan model berkebangsaan Iran. Televisi Tahun Serial Peran Saluran 2010 Sapna Babul Ka...Bidaai Guni Star Plus 2011 Sanskaar Laxmi Randhal Zee TV 2012 Shubh Vivah Karuna Saxena SET India 2012 Fear Files Neha Paranjape Zee TV 2012 Teri Meri Love Stories Pari Star Plus 2012 Love Marriage Ya Arranged Marriage Pooja SET India 2013 Madventures Diri (Kontestan) ARY Digita...

 

 

Kerkion

Theseus melawan Kerkion. Kerkion (Κερκύων) adalah salah satu tokoh dalam mitologi Yunani dan merupakan raja Eleusis. Orang tua Kerkion menurut beberapa versi yaitu: Poseidon dan salah satu anak Amfiktion,[1] atau Poseidon dan nimfa Argiope,[2] atau Brankhus dan nimfa Argiope,[3] atau Hefaistos.[4] Kerkion mempunyai dua orang anak yaitu Alope dan Hippothous. Kerkion sering berdiri di jalan-jalan Eleusis dan menantang gulat pada orang yang lewat. Dia berja...

 

 

Associazione Calcio Napoli 1950-1951

Voce principale: Società Sportiva Calcio Napoli. AC NapoliStagione 1950-1951 Sport calcio Squadra Napoli Allenatore Eraldo Monzeglio Presidente Egidio Musollino Serie A6º Maggiori presenzeCampionato: Gramaglia (38)Totale: Gramaglia (38) Miglior marcatoreCampionato: Amadei (11)Totale: Amadei (11) StadioArturo Collana 1949-1950 1951-1952 Si invita a seguire il modello di voce Questa voce raccoglie le informazioni riguardanti l'Associazione Calcio Napoli nelle competizioni ufficiali ...

Bacino Permiano

Questa voce sugli argomenti Texas e geologia è solo un abbozzo. Contribuisci a migliorarla secondo le convenzioni di Wikipedia. Segui i suggerimenti del progetto di riferimento. Il Bacino Permiano (in inglese Permian Basin) è un bacino sedimentario che si estende nella parte occidentale del Texas e in Nuovo Messico. Il bacino, il cui nome deriva da Permiano, un'era geologica, è un importante giacimento di idrocarburi. Mappa del Bacino Permiano, in rosso la parte sempre inclusa, in ro...

 

 

Plinio il Giovane

Plinio il Giovane(Gaio Plinio Cecilio Secondo)Console dell'Impero romanoStatua di Plinio il Giovane sulla facciata della Cattedrale di Santa Maria Assunta (Duomo) a Como, in Italia Nome originaleGaio Cecilio (alla nascita)Gaio Plinio Cecilio Secondo (dopo l'adozione) Nascita61[1][2] o 62[1][2]Como[1][2] (Novum Comum[2]) Morte114 circa[1][2]in Bitinia[1][2] o a Roma[1] Coniuge1ª: Giovane donna...

 

 

Whipped cream

Cream whipped until semi-solid For other uses, see Whipped cream (disambiguation). Whipping cream redirects here. For the definitions of whipping cream used in various countries, see Cream § Types. Whipped creamA cup of hot chocolate topped with whipped cream from a pressurized canTypeCreamMain ingredientsCreamVariationsAdded sugar and other flavorings, such as vanilla Cookbook: Whipped cream  Media: Whipped cream Apple crisp with whipped cream Whipped cream is heavy, double, o...

American Daylight

American DaylightPoster rilis asliSutradaraRoger ChristianDitulis olehFarrukh DhondyPemeranNick MoranKoel PuriePenata musikAmaan Ali BangashAyaan Ali BangashSinematograferHinman DhamijaPenyuntingAlan StrachanDistributorKaleidoscope EntertainmentTanggal rilis2004Durasi98 minutesNegaraUnited StatesBahasaEnglish American Daylight adalah film Amerika Serikat produksi tahun 2004 yang disutradarai oleh Roger Christian berdasarakan skenario yang ditulis oleh Farrukh Dhondy, dan diproduseri ole...

 

 

A Crystal Age

A Crystal Age Edisi 1906PengarangW. H. HudsonNegaraBritania RayaBahasaInggrisGenreFiksi utopiaFiksi ilmiahBelles-lettresPenerbitT. Fisher UnwinTanggal terbit1887Jenis mediaCetak (Sampul keras)Halaman287 pp. A Crystal Age adalah novel utopia/Distopia yang ditulis oleh W. H. Hudson, pertama kali diterbitkan pada tahun 1887.[1] Buku ini disebut sebagai tonggak sejarah fiksi ilmiah yang signifikan[2] dan terkenal karena antisipasinya terhadap mistisisme ekologi modern ya...

 

 

Gook (headgear)

Cornish dancers wearing Gooks with stiffened cardboard Bal maidens wearing gooks, 1890 A gook was a piece of protective headgear worn by bal maidens (female manual labourers in the mining industries of Cornwall and Devon).[1] The gook was a bonnet which covered the head and projected forward over the face, to protect the wearer's head and face from sunlight and flying debris.[1][2] Bal maidens often worked outdoors or in very crude surface-level shelters,[3] a...

Максимово (Кемеровская область)

У этого термина существуют и другие значения, см. Максимово. ДеревняМаксимово 54°49′44″ с. ш. 86°31′49″ в. д.HGЯO Страна  Россия Субъект Федерации Кемеровская область Муниципальный район Крапивинский Сельское поселение Борисовское История и география Высота цен�...

 

 

Rubric

Word or section of text that is traditionally written or printed in red ink for emphasis This article is about rubrics in text and as instructions. For other uses, see Rubric (disambiguation). Dominican Missal, c. 1240, with rubrics in red (Historical Museum of Lausanne) Rubrics in an illuminated gradual of c. 1500 A rubric is a word or section of text that is traditionally written or printed in red ink for emphasis. The word derives from the Latin rubrica, meaning red ochre or red chalk,[...

 

 

University of Bristol

Research university located in Bristol, England Bristol University redirects here. For the university in Anaheim, California, see Bristol University (California). For the university in Bristol, Tennessee, see Bristol University (Tennessee). University of BristolLatin: Universitas BristolliensisMottoLatin: Vim promovet insitamMotto in English[Learning] promotes one's innate power (from Horace, Ode 4.4)[1]TypePublic red brick research universityEstablished1595 – Merchant Venturer...

Martin Lewis Perl

Cet article est une ébauche concernant un physicien américain. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Pour les articles homonymes, voir Perl. Martin Lewis PerlBiographieNaissance 24 juin 1927New York, États-UnisDécès 30 septembre 2014 (à 87 ans)Palo Alto, États-UnisNationalité  AméricainFormation Université ColumbiaAcadémie de la marine marchande des États-UnisÉcole d'ingénierie ...

 

 

Our Lady of Good Health Church, Pattumala

Church in Pattumala, IndiaPattumala Matha Pilgrim Shrine (Also Known as Kochu Velankanni; Our Lady of Health Church , Pattumala)Pattumala Matha Pilgrim ShrinePattumala Matha Pilgrim ShrinePattumala Matha Pilgrim Shrine (Also Known as Kochu Velankanni; Our Lady of Health Church , Pattumala)9°34′44″N 77°02′04″E / 9.5790238°N 77.0344959°E / 9.5790238; 77.0344959LocationPattumalaCountryIndiaDenominationRoman CatholicWebsitewww.pattumalamatha.comHistoryCult(s) ...