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Expedition 66
	Promotional poster
Mission type	Long-duration expedition
Operator	NASA / Roscosmos
Mission duration	164 days, 6 hours and 7 minutes
Expedition
Space station	International Space Station
Began	17 October 2021, 01:14 UTC
Ended	30 March 2022, 07:21:03
Arrived aboard	Soyuz MS-18; SpaceX Crew-2; Soyuz MS-19; SpaceX Crew-3; Soyuz MS-21
Departed aboard	SpaceX Crew-2; Soyuz MS-19
Crew
Crew size	7-10
Members	Expedition 65/66:; Shane Kimbrough; Megan McArthur; Akihiko Hoshide; Thomas Pesquet; Anton Shkaplerov; Expedition 64/65/66:; Pyotr Dubrov; Mark T. Vande Hei; Expedition 66/67:; Raja Chari; Thomas Marshburn; Matthias Maurer; Kayla Barron; Oleg Artemyev; Denis Matveev; Sergey Korsakov;
EVAs	4
EVA duration	25 hours 31 minutes
	; Expedition 66 mission patch, resembling that of U.S. Route 66; ; Expedition 66 crew portrait ISS expeditions ← Expedition 65 Expedition 67 →

Expedition 66 was the 66th long-duration expedition to the International Space Station. The mission began after the departure of Soyuz MS-18 on 17 October 2021.^[2] It was commanded by European Space Agency astronaut Thomas Pesquet, the fourth European astronaut and first French astronaut to command the ISS^[3] until 8 November 2021 when Russian cosmonaut Anton Shkaplerov, who arrived aboard Soyuz MS-19, took over his command.^[4]

Pesquet was transported to the ISS on SpaceX Crew-2 in April 2021, joined by NASA astronauts Shane Kimbrough and Megan McArthur and Japan Aerospace Exploration Agency (JAXA) astronaut Akihiko Hoshide.^[5] Crew-2 from Expedition 65 extended their tour of duty on the ISS to become part of Expedition 66,^[6] along with Russian cosmonaut Pyotr Dubrov and NASA astronaut Mark Vande Hei, who both launched on Soyuz MS-18 and returned to Earth on Soyuz MS-19, following their extended mission. Russian cosmonaut Shkaplerov launched on Soyuz MS-19, along with two participants in the joint film project between Roscosmos and Channel One, The Challenge: film director Klim Shipenko and actress Yulia Peresild.

SpaceX Crew-3, launched 10 November 2021, carried NASA astronauts Raja Chari, Thomas Marshburn, and Kayla Barron and ESA astronaut Matthias Maurer to the ISS.^[7] At the end of Expedition 66, they remained on the ISS as part of Expedition 67 while Dubrov and Vande Hei returned to Earth aboard Soyuz MS-19.^[8] However, continued international collaboration has been thrown into doubt by the 2022 Russian invasion of Ukraine and related sanctions on Russia.^[9]

Crew

Flight	Astronaut	First part (17 October – 8 November 2021)	Second part (8–11 November 2021)^[10]	Third part (11 November 2021 – 18 March 2022)	Fourth part (18 – 30 March 2022)
Soyuz MS-19	Anton Shkaplerov, Roscosmos Fourth and last spaceflight	Flight Engineer	Commander
	Pyotr Dubrov, Roscosmos First spaceflight	Flight Engineer
	Mark T. Vande Hei, NASA Second spaceflight	Flight Engineer
SpaceX Crew-2	Shane Kimbrough, NASA Third and last spaceflight	Flight Engineer	Off Station
	Megan McArthur, NASA Second spaceflight	Flight Engineer	Off Station
	Akihiko Hoshide, JAXA Third spaceflight	Flight Engineer	Off Station
	Thomas Pesquet, ESA Second spaceflight	Commander	Off Station
SpaceX Crew-3	Raja Chari, NASA First spaceflight	Off Station		Flight Engineer
	Thomas Marshburn, NASA Third and last spaceflight	Off Station		Flight Engineer
	Matthias Maurer, ESA First spaceflight	Off Station		Flight Engineer
	Kayla Barron, NASA First spaceflight	Off Station		Flight Engineer
Soyuz MS-21	Oleg Artemyev, Roscosmos Third spaceflight	Off Station			Flight Engineer
	Denis Matveev, Roscosmos Only spaceflight	Off Station			Flight Engineer
	Sergey Korsakov, Roscosmos First spaceflight	Off Station			Flight Engineer

Notes

^ The European portion of SpaceX Crew-2 is called Alpha and is headed by Thomas Pesquet.
^ The European portion of SpaceX Crew-3 is called Cosmic Kiss, which is headed by Matthias Maurer.