CC-preferring endodeoxyribonuclease

CC-preferring endodeoxyribonuclease
Identifiers
EC no.3.1.21.6
CAS no.37211-67-9
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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CC-preferring endodeoxyribonuclease (EC 3.1.21.6, Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC

This enzyme has preference for CC sites in double-stranded circular and linear DNA.

References

  1. ^ Xia YN, Morgan R, Schildkraut I, Van Etten JL (1988). "A site-specific single-strand endonuclease activity induced by NYs-1 virus-infection of a Chlorella-like green-alga". Nucleic Acids Res. 16 (20): 9477–9487. doi:10.1093/nar/16.20.9477. PMC 338757. PMID 3186439.
  2. ^ Aparicio JF, Freije JM, Lopez-Otin C, Cal S, Sanchez J (1992). "A Streptomyces glaucescens endodeoxyribonuclease which shows a strong preference for CC dinucleotide". Eur. J. Biochem. 205 (2): 695–699. doi:10.1111/j.1432-1033.1992.tb16831.x. PMID 1533367.