Aspergillus deoxyribonuclease K1

Aspergillus deoxyribonuclease K1
Identifiers
EC no.3.1.22.2
CAS no.264922-12-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

Aspergillus deoxyribonuclease K1 (EC 3.1.22.2, Aspergillus DNase K1) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products

This enzyme has preference for single-stranded DNA.

References

  1. ^ Kato M, Ikeda Y (1968). "On the deoxyribonucleases, K1 and K2, isolated from mycelia of Aspergillus oryzae. I. Isolation and purification of DNases K1 and K2". J. Biochem. 64 (3): 321–8. PMID 4303413.
  2. ^ Shishido K, Kato M, Ikeda Y (1968). "Isolation of thymidylic acid-rich fragments from double-stranded deoxyribonucleic acids". J. Biochem. 65: 479–481.