Amoeba

This article is about the cellular body type. For the genus, see Amoeba (genus). For other uses, see Amoeba (disambiguation).

Clockwise from top right: Amoeba proteus, Actinophrys sol, Acanthamoeba sp., Nuclearia thermophila., Euglypha acanthophora, neutrophil ingesting bacteria.

An amoeba (/əˈmiːbə/; less commonly spelled ameba or amœba; pl.: amoebas (less commonly, amebas) or amoebae (amebae) /əˈmiːbi/),[1] often called an amoeboid, is a type of cell or unicellular organism with the ability to alter its shape, primarily by extending and retracting pseudopods.[2] Amoebae do not form a single taxonomic group; instead, they are found in every major lineage of eukaryotic organisms. Amoeboid cells occur not only among the protozoa, but also in fungi, algae, and animals.[3][4][5][6][7]

Microbiologists often use the terms "amoeboid" and "amoeba" interchangeably for any organism that exhibits amoeboid movement.[8][9]

In older classification systems, most amoebae were placed in the class or subphylum Sarcodina, a grouping of single-celled organisms that possess pseudopods or move by protoplasmic flow. However, molecular phylogenetic studies have shown that Sarcodina is not a monophyletic group whose members share common descent. Consequently, amoeboid organisms are no longer classified together in one group.[10]

The best known amoeboid protists are Chaos carolinense and Amoeba proteus, both of which have been widely cultivated and studied in classrooms and laboratories.[11][12] Other well known species include the so-called "brain-eating amoeba" Naegleria fowleri, the intestinal parasite Entamoeba histolytica, which causes amoebic dysentery, and the multicellular "social amoeba" or slime mould Dictyostelium discoideum.

Biology

Pseudopods and movement

The forms of pseudopodia, from left: polypodial and lobose; monopodial and lobose; filose; conical; reticulose; tapering actinopods; non-tapering actinopods

Amoeba do not have cell walls, which allows for free movement. Amoeba move and feed by using pseudopods, which are bulges of cytoplasm formed by the coordinated action of actin microfilaments pushing out the plasma membrane that surrounds the cell.[13] The appearance and internal structure of pseudopods are used to distinguish groups of amoebae from one another. Amoebozoan species, such as those in the genus Amoeba, typically have bulbous (lobose) pseudopods, rounded at the ends and roughly tubular in cross-section. Cercozoan amoeboids, such as Euglypha and Gromia, have slender, thread-like (filose) pseudopods. Foraminifera emit fine, branching pseudopods that merge with one another to form net-like (reticulose) structures. Some groups, such as the Radiolaria and Heliozoa, have stiff, needle-like, radiating axopodia (actinopoda) supported from within by bundles of microtubules.[3][14]

Naked amoeba in the genus Mayorella
Shell of the testate amoeba Cylindrifflugia acuminata
"Naked" amoeba of the genus Mayorella (left) and shell of the testate amoeba Cylindrifflugia acuminata (right)

Free-living amoebae may be "testate" (enclosed within a hard shell), or "naked" (also known as gymnamoebae, lacking any hard covering). The shells of testate amoebae may be composed of various substances, including calcium, silica, chitin, or agglutinations of found materials like small grains of sand and the frustules of diatoms.[15]

To regulate osmotic pressure, most freshwater amoebae have a contractile vacuole which expels excess water from the cell.[16] This organelle is necessary because freshwater has a lower concentration of solutes (such as salt) than the amoeba's own internal fluids (cytosol). Because the surrounding water is hypotonic with respect to the contents of the cell, water is transferred across the amoeba's cell membrane by osmosis. Without a contractile vacuole, the cell would fill with excess water and, eventually, burst. Marine amoebae do not usually possess a contractile vacuole because the concentration of solutes within the cell are in balance with the tonicity of the surrounding water.[17]

Nutrition

Amoeba phagocytosis of a bacterium

The food sources of amoebae vary. Some amoebae are predatory and live by consuming bacteria and other protists. Some are detritivores and eat dead organic material.

Amoebae typically ingest their food by phagocytosis, extending pseudopods to encircle and engulf live prey or particles of scavenged material. Amoeboid cells do not have a mouth or cytostome, and there is no fixed place on the cell at which phagocytosis normally occurs.[18]

Some amoebae also feed by pinocytosis, imbibing dissolved nutrients through vesicles formed within the cell membrane.[19]

Size range

Foraminifera have reticulose (net-like) pseudopods, and many species are visible with the naked eye.

The size of amoeboid cells and species is extremely variable. The marine amoeboid Massisteria voersi is just 2.3 to 3 micrometres in diameter,[20] within the size range of many bacteria.[21] At the other extreme, the shells of deep-sea xenophyophores can attain 20 cm in diameter.[22] Most of the free-living freshwater amoebae commonly found in pond water, ditches, and lakes are microscopic, but some species, such as the so-called "giant amoebae" Pelomyxa palustris and Chaos carolinense, can be large enough to see with the naked eye.

Species or cell type Size in micrometers
Massisteria voersi[20] 2.3–3
Naegleria fowleri[23] 8–15
Neutrophil (white blood cell)[24] 12–15
Acanthamoeba[25] 12–40
Entamoeba histolytica[26] 15–60
Arcella vulgaris[27] 30–152
Amoeba proteus[28] 220–760
Chaos carolinense[29] 700–2000
Pelomyxa palustris[30] up to 5000
Syringammina fragilissima[22] up to 200000

Sexual reproduction

Recent evidence indicates that several Amoebozoa lineages undergo meiosis.

Orthologs of genes employed in meiosis of sexual eukaryotes have recently been identified in the Acanthamoeba genome. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh and Mlh.[31] This finding suggests that the ‘'Acanthamoeba'’ are capable of some form of meiosis and may be able to undergo sexual reproduction.

The meiosis-specific recombinase, Dmc1, is required for efficient meiotic homologous recombination, and Dmc1 is expressed in Entamoeba histolytica.[32] The purified Dmc1 from E. histolytica forms presynaptic filaments and catalyses ATP-dependent homologous DNA pairing and DNA strand exchange over at least several thousand base pairs.[32] The DNA pairing and strand exchange reactions are enhanced by the eukaryotic meiosis-specific recombination accessory factor (heterodimer) Hop2-Mnd1.[32] These processes are central to meiotic recombination, suggesting that E. histolytica undergoes meiosis.[32]

Studies of Entamoeba invadens found that, during the conversion from the tetraploid uninucleate trophozoite to the tetranucleate cyst, homologous recombination is enhanced.[33] Expression of genes with functions related to the major steps of meiotic recombination also increase during encystations.[33] These findings in E. invadens, combined with evidence from studies of E. histolytica indicate the presence of meiosis in the Entamoeba.

Dictyostelium discoideum in the supergroup Amoebozoa can undergo mating and sexual reproduction including meiosis when food is scarce.[34][35]

Since the Amoebozoa diverged early from the eukaryotic family tree, these results suggest that meiosis was present early in eukaryotic evolution. Furthermore, these findings are consistent with the proposal of Lahr et al.[36] that the majority of amoeboid lineages are anciently sexual.

Ecology

Pathogenic amoebae

Trophozoites of the pathogenic Entamoeba histolytica with ingested red blood cells

Some amoebae can infect other organisms pathogenically, causing disease:[37][38][39][40]

Amoeba have been found to harvest and grow the bacteria implicated in plague.[41] Amoebae can likewise play host to microscopic organisms that are pathogenic to people and help in spreading such microbes. Bacterial pathogens (for example, Legionella) can oppose absorption of food when devoured by amoebae.[42] The currently generally utilized and best-explored amoebae that host other organisms are Acanthamoeba castellanii and Dictyostelium discoideum.[43] Microorganisms that can overcome the defenses of one-celled organisms can shelter and multiply inside them, where they are shielded from unfriendly outside conditions by their hosts.

History of knowledge and classification

Conceptual origins

The first illustration of an amoeboid, from Rösel von Rosenhof's Insecten-Belustigung (1755)

The earliest record of an amoeboid organism was produced in 1755 by August Johann Rösel von Rosenhof, who named his discovery "Der Kleine Proteus" ("the Little Proteus").[44] Rösel's illustrations show an unidentifiable freshwater amoeba, similar in appearance to the common species now known as Amoeba proteus.[45] The term "Proteus animalcule" remained in use throughout the 18th and 19th centuries, as an informal name for any large, free-living amoeboid.[46]

In 1822, the genus Amiba (from the Greek ἀμοιβή amoibe, meaning "change") was erected by the French naturalist Bory de Saint-Vincent.[47][48] Bory's contemporary, C. G. Ehrenberg, adopted the genus in his own classification of microscopic creatures, but changed the spelling to Amoeba.[49]

In 1841, Félix Dujardin coined the term "sarcode" (from Greek σάρξ sarx, "flesh," and εἶδος eidos, "form") for the "thick, glutinous, homogeneous substance" which fills protozoan cell bodies.[50]: 26  Although the term originally referred to the protoplasm of any protozoan, it soon came to be used in a restricted sense to designate the gelatinous contents of amoeboid cells.[10] Thirty years later, the Austrian zoologist Ludwig Karl Schmarda used "sarcode" as the conceptual basis for his division Sarcodea, a phylum-level group made up of "unstable, changeable" organisms with bodies largely composed of "sarcode".[51]: 156  Later workers, including the influential taxonomist Otto Bütschli, amended this group to create the class Sarcodina,[52]: 1  a taxon that remained in wide use throughout most of the 20th century.[53]

Traditional classification

Examples of different kinds of amoebae
Amoeba proteus, a gymnamoeba
Actinophrys sol, a heliozoan
Naegleria lustrarea, a heterolobosean
Vampyrella lateritia, a proteomyxid
Euglypha ciliata, a filose testate amoeba
Hyalosphenia papilio, a lobose testate amoeba
Reticulomyxa filosa, a reticulose amoeba
Dictyostelium discoideum, an eumycetozoan

For convenience, all amoebae were grouped as Sarcodina and generally divided into morphological categories, on the basis of the form and structure of their pseudopods. Amoebae with pseudopods supported by regular arrays of microtubules (such as the freshwater Heliozoa and marine Radiolaria) were classified as Actinopoda, whereas those with unsupported pseudopods were classified as Rhizopoda.[54] The Rhizopods were further subdivided into lobose, filose, plasmodial and reticulose, according to the morphology of their pseudopods. During the 1980s, taxonomists reached the following classification, based exclusively on morphological comparisons:[55][53]

  • Sarcodina Schmarda 1871: all amoebae.[55]: 40 
  • Rhizopoda von Siebold 1845: amorphous amoebae that lack axopodia and move through pseudopodia.[55]: 41 [53]: 202 
  • Heterolobosea Page & Blanton 1985: amoebae with eruptive pseudopodia, similar to the lobose ones but with a distinct movement, and usually with flagellate life stages. It was traditionally divided into those which aggregate to form fruiting bodies (Acrasida) and those that do not (Schizopyrenida).[53]: 203–204 
  • Caryoblastea Margulis 1974: amoebae with sparse, non-motile flagella on the surface. This group only includes the order Pelobiontida,[53]: 207  which now belongs to the amoebozoan group Archamoebae together with some naked amoebae.[56]
  • Eumycetozoea Zopf 1885: plasmodial amoebae with filiform subpseudopodia that produce fruiting bodies.
  • Plasmodiophorea Cook 1928: endoparasitic plasmodial amoebae with minute pseudopodia. This group is now an order within Rhizaria, closely related to the endoparasites Phagomyxida.
  • Filosea Leidy 1879: amoebae with filose pseudopodia.
  • Aconchulinia de Saedeleer 1934: filose naked amoebae, sometimes covered in scales. This group included two unrelated taxa: the nucleariid amoebae, closely related to fungi; and most of the Vampyrellida, found in Rhizaria.
  • Testaceafilosia de Saedeleer 1934: filose testate amoebae. This group included taxa now found throughout Rhizaria, such as Gromiida and Euglyphida.
  • Granuloreticulosea de Saedeleer 1934: amoebae with delicate granular pseudopodia. This group included both the Foraminifera (now in Rhizaria) and some members of Vampyrellida.
  • Xenophyophorea Schulze 1904: plasmodial amoebae enclosed in a branched-tube system composed of a transparent organic substance. This group is now fully integrated into the Foraminifera.

Transitional period

Eukaryotes

Archezoa

Percolozoa (Heterolobosea)  

other excavates

Eosarcodina

Neosarcodina

Sarcodina
The 'amoeboflagellate' hypothesis by Thomas Cavalier-Smith, where higher eukaryotes evolved from amoeboid phyla.[57]: 244 

In the final decades of the 20th century, a series of molecular phylogenetic analyses confirmed that Sarcodina was not a monophyletic group, and that amoebae evolved from flagellate ancestors.[10] The protozoologist Thomas Cavalier-Smith proposed that the ancestor of most eukaryotes was an amoeboflagellate much like modern heteroloboseans, which in turn gave rise to a paraphyletic Sarcodina from which other groups (e.g., alveolates, animals, plants) evolved by a secondary loss of the amoeboid phase. In his scheme, the Sarcodina were divided into the more primitive Eosarcodina (with the phyla Reticulosa and Mycetozoa) and the more derived Neosarcodina (with the phyla Amoebozoa for lobose amoebae and Rhizopoda for filose amoebae).[57]

Shortly after, phylogenetic analyses disproved this hypothesis, as non-amoeboid zooflagellates and amoeboflagellates were found to be completely intermingled with amoebae. With the addition of many flagellates to Rhizopoda and the removal of some amoebae, the name was rejected in favour of a new name Cercozoa. As such, both names Rhizopoda and Sarcodina were finally abandoned as formal taxa, but they remained useful as descriptive terms for amoebae.[58]: 238  The phylum Amoebozoa was conserved, as it still primarily included amoeboid organisms, and now included the Mycetozoa.[58]: 232 

Current classification

Today, amoebae are dispersed among many high-level taxonomic groups. The majority of traditional sarcodines are placed in two eukaryote supergroups: Amoebozoa and Rhizaria. The rest have been distributed among the excavates, opisthokonts, stramenopiles and minor clades.[10][59]

  • Amoebozoa Lühe 1913 em. Cavalier-Smith 1998: includes all naked and testate lobose amoebae (traditional Lobosea) as well as the pelobionts and eumycetozoans, and a few flagellates.[60]: 17 
  • Heterolobosea Page & Blanton 1985: amoebae with lobose pseudopodia but eruptive flow of cytoplasm. Currently it includes the aggregative Acrasida, as well as several other amoeboflagellates. They are a class of excavates closely related to Euglenozoa, with whom they share their characteristic discoidal mitochondrial cristae.[10]: 293 
  • Rotosphaerida Rainer 1968: also known as nucleariids, includes a few filose amoebae traditionally classified within the Filosea, positioned as the sister group of Fungi.[63]

The following cladogram shows the sparse positions of amoeboid groups (in bold), based on molecular phylogenetic analyses:[66]

Eukaryotes

Amoeboid cells in other organisms

Neutrophil (white blood cell) engulfing anthrax bacteria

Amoeboid cell types in multicellular organisms

Some multicellular organisms have amoeboid cells only in certain phases of life, or use amoeboid movements for specialized functions. In the immune system of humans and other animals, amoeboid white blood cells pursue invading organisms, such as bacteria and pathogenic protists, and engulf them by phagocytosis.[68] Sponges exhibit a totipotent cell type known as archaeocytes, capable of transforming into the feeding cells or choanocytes.[69]

Amoeboid dispersal stages

Amoeboid stages also occur in the multicellular fungus-like protists, the so-called slime moulds. Both the plasmodial slime moulds, currently classified in the class Myxogastria, and the cellular slime moulds of the groups Acrasida and Dictyosteliida, live as amoebae during their feeding stage. The amoeboid cells of the former combine to form a giant multinucleate organism,[70] while the cells of the latter live separately until food runs out, at which time the amoebae aggregate to form a multicellular migrating "slug" which functions as a single organism.[8]

Other organisms may also present amoeboid cells during certain life-cycle stages, e.g., the gametes of some green algae (Zygnematophyceae)[71] and pennate diatoms,[72] the spores (or dispersal phases) of some Mesomycetozoea,[73][74] and the sporoplasm stage of Myxozoa and of Ascetosporea.[75]

References

  1. ^ "Amoeba" Archived 22 November 2015 at the Wayback Machine at Oxforddictionaries.com
  2. ^ Singleton, Paul (2006). Dictionary of Microbiology and Molecular Biology, 3rd Edition, revised. Chichester, UK: John Wiley & Sons. pp. 32. ISBN 978-0-470-03545-0.
  3. ^ a b David J. Patterson. "Amoebae: Protists Which Move and Feed Using Pseudopodia". Tree of Life web project. Archived from the original on 15 June 2010. Retrieved 21 September 2009.
  4. ^ "The Amoebae". The University of Edinburgh. Archived from the original on 10 June 2009.
  5. ^ Wim van Egmond. "Sun animalcules and amoebas". Microscopy-UK. Archived from the original on 4 November 2005. Retrieved 23 October 2005.
  6. ^ Flor-Parra, Ignacio; Bernal, Manuel; Zhurinsky, Jacob; Daga, Rafael R. (17 December 2013). "Cell migration and division in amoeboid-like fission yeast". Biology Open. 3 (1): 108–115. doi:10.1242/bio.20136783. ISSN 2046-6390. PMC 3892166. PMID 24357230.
  7. ^ Friedl, P.; Borgmann, S.; Bröcker, E. B. (1 October 2001). "Amoeboid leukocyte crawling through extracellular matrix: lessons from the Dictyostelium paradigm of cell movement". Journal of Leukocyte Biology. 70 (4): 491–509. doi:10.1189/jlb.70.4.491. ISSN 0741-5400. PMID 11590185. S2CID 28731650.
  8. ^ a b Marée, Athanasius FM; Hogeweg, Paulien (2001). "How amoeboids self-organize into a fruiting body: multicellular coordination in Dictyostelium discoideum". Proceedings of the National Academy of Sciences. 98 (7): 3879–3883. doi:10.1073/pnas.061535198. PMC 31146. PMID 11274408.
  9. ^ Mackerras, M. J.; Ercole, Q. N. (1947). "Observations on the action of paludrine on malarial parasites". Transactions of the Royal Society of Tropical Medicine and Hygiene. 41 (3): 365–376. doi:10.1016/s0035-9203(47)90133-8. PMID 18898714.
  10. ^ a b c d e f g Pawlowski, Jan (2008). "The twilight of Sarcodina: a molecular perspective on the polyphyletic origin of amoeboid protists" (PDF). Protistology. 5 (4): 281–302.
  11. ^ Tan; et al. (2005). "A simple mass culture of the amoeba Chaos carolinense: revisit" (PDF). Protistology. 4: 185–90. Archived (PDF) from the original on 29 September 2017. Retrieved 28 September 2017.
  12. ^ "Relationship with Humans". Amoeba proteus. 12 April 2013. Archived from the original on 29 September 2017. Retrieved 28 September 2017.
  13. ^ Alberts Eds.; et al. (2007). Molecular Biology of the Cell 5th Edition. New York: Garland Science. p. 1037. ISBN 9780815341055.
  14. ^ Margulis, Lynn (2009). Kingdoms and Domains. Academic Press. pp. 206–7. ISBN 978-0-12-373621-5.
  15. ^ Ogden, C. G. (1980). An Atlas of Freshwater Testate Amoeba. Oxford, London, and Glasgow: Oxford University Press, for British Museum (Natural History). pp. 1–5. ISBN 978-0198585022.
  16. ^ Alberts Eds.; et al. (2007). Molecular Biology of the Cell 5th Edition. New York: Garland Science. p. 663. ISBN 9780815341055.
  17. ^ Kudo, Richard Roksabro. "Protozoology." Protozoology 4th Edit (1954). p. 83
  18. ^ Thorp, James H. (2001). Ecology and Classification of North American Freshwater Invertebrates. San Diego: Academic. p. 71. ISBN 0-12-690647-5.
  19. ^ Jeon, Kwang W. (1973). Biology of Amoeba. New York: Academic Press. pp. 100. ISBN 9780123848505.
  20. ^ a b Mylnikov, Alexander P.; Weber, Felix; Jürgens, Klaus; Wylezich, Claudia (1 August 2015). "Massisteria marina has a sister: Massisteria voersi sp. nov., a rare species isolated from coastal waters of the Baltic Sea". European Journal of Protistology. 51 (4): 299–310. doi:10.1016/j.ejop.2015.05.002. ISSN 1618-0429. PMID 26163290.
  21. ^ "The Size, Shape, And Arrangement of Bacterial Cells". classes.midlandstech.edu. Archived from the original on 9 August 2016. Retrieved 21 August 2016.
  22. ^ a b Gooday, A. J.; Aranda da Silva, A.; Pawlowski, J. (1 December 2011). "Xenophyophores (Rhizaria, Foraminifera) from the Nazaré Canyon (Portuguese margin, NE Atlantic)". Deep-Sea Research Part II: Topical Studies in Oceanography. The Geology, Geochemistry, and Biology of Submarine Canyons West of Portugal. 58 (23–24): 2401–2419. Bibcode:2011DSRII..58.2401G. doi:10.1016/j.dsr2.2011.04.005.
  23. ^ "Brain-Eating Amoeba (Naegleria Fowleri): Causes and Symptoms". Archived from the original on 21 August 2016. Retrieved 21 August 2016.
  24. ^ "Anatomy Atlases: Atlas of Microscopic Anatomy: Section 4: Blood". www.anatomyatlases.org. Archived from the original on 19 August 2016. Retrieved 21 August 2016.
  25. ^ "Acanthamoeba | Microworld". www.arcella.nl. Archived from the original on 18 August 2016. Retrieved 21 August 2016.
  26. ^ "Microscopy of Entamoeba histolytica". msu.edu. Archived from the original on 5 October 2016. Retrieved 21 August 2016.
  27. ^ "Arcella vulgaris | Microworld". www.arcella.nl. Archived from the original on 18 August 2016. Retrieved 21 August 2016.
  28. ^ "Amoeba proteus | Microworld". www.arcella.nl. Archived from the original on 18 August 2016. Retrieved 21 August 2016.
  29. ^ "Chaos | Microworld". www.arcella.nl. Archived from the original on 12 October 2016. Retrieved 21 August 2016.
  30. ^ "Pelomyxa palustris | Microworld". www.arcella.nl. Archived from the original on 18 August 2016. Retrieved 21 August 2016.
  31. ^ Khan NA, Siddiqui R (2015). "Is there evidence of sexual reproduction (meiosis) in Acanthamoeba?". Pathog Glob Health. 109 (4): 193–5. doi:10.1179/2047773215Y.0000000009. PMC 4530557. PMID 25800982.
  32. ^ a b c d Kelso AA, Say AF, Sharma D, Ledford LL, Turchick A, Saski CA, King AV, Attaway CC, Temesvari LA, Sehorn MG (2015). "Entamoeba histolytica Dmc1 Catalyzes Homologous DNA Pairing and Strand Exchange That Is Stimulated by Calcium and Hop2-Mnd1". PLOS ONE. 10 (9): e0139399. Bibcode:2015PLoSO..1039399K. doi:10.1371/journal.pone.0139399. PMC 4589404. PMID 26422142.
  33. ^ a b Singh N, Bhattacharya A, Bhattacharya S (2013). "Homologous recombination occurs in Entamoeba and is enhanced during growth stress and stage conversion". PLOS ONE. 8 (9): e74465. Bibcode:2013PLoSO...874465S. doi:10.1371/journal.pone.0074465. PMC 3787063. PMID 24098652.
  34. ^ Flowers JM, Li SI, Stathos A, Saxer G, Ostrowski EA, Queller DC, Strassmann JE, Purugganan MD (2010). "Variation, sex, and social cooperation: molecular population genetics of the social amoeba Dictyostelium discoideum". PLOS Genet. 6 (7): e1001013. doi:10.1371/journal.pgen.1001013. PMC 2895654. PMID 20617172.
  35. ^ O'Day DH, Keszei A (2012). "Signalling and sex in the social amoebozoans". Biol Rev Camb Philos Soc. 87 (2): 313–29. doi:10.1111/j.1469-185X.2011.00200.x. PMID 21929567. S2CID 205599638.
  36. ^ Lahr DJ, Parfrey LW, Mitchell EA, Katz LA, Lara E (2011). "The chastity of amoebae: re-evaluating evidence for sex in amoeboid organisms". Proc. Biol. Sci. 278 (1715): 2081–90. doi:10.1098/rspb.2011.0289. PMC 3107637. PMID 21429931.
  37. ^ Casadevall A (2008) Evolution of intracellular pathogens. Annu Rev Microbiol 62: 19–33. 10.1146/annurev.micro.61.080706.093305 [PubMed] [CrossRef] [Google Scholar]
  38. ^ Guimaraes AJ, Gomes KX, Cortines JR, Peralta JM, Peralta RHS (2016) Acanthamoeba spp. as a universal host for pathogenic microorganisms: One bridge from environment to host virulence. Microbiological Research 193: 30–38. 10.1016/j.micres.2016.08.001 [PubMed] [CrossRef] [Google Scholar]
  39. ^ Hilbi H, Weber SS, Ragaz C, Nyfeler Y, Urwyler S (2007) Environmental predators as models for bacterial pathogenesis. Environmental microbiology 9: 563–575. 10.1111/j.1462-2920.2007.01238.x [PubMed] [CrossRef] [Google Scholar]
  40. ^ Greub, G; Raoult, D (2004). "Microorganisms resistant to free-living amoebae". Clinical Microbiology Reviews. 17 (2): 413–433. doi:10.1128/CMR.17.2.413-433.2004. PMC 387402. PMID 15084508.
  41. ^ "Are amoebae safe harbors for plague? New research shows that plague bacteria not only survive, but thrive and replicate once ingested by an amoeba".
  42. ^ Vidyasagar, Aparna (April 2016). "What Is an Amoeba?". livescience.com. Retrieved 8 November 2020.
  43. ^ Thewes, Sascha; Soldati, Thierry; Eichinger, Ludwig (2019). "Editorial: Amoebae as Host Models to Study the Interaction with Pathogens". Frontiers in Cellular and Infection Microbiology. 9: 47. doi:10.3389/fcimb.2019.00047. PMC 6433779. PMID 30941316.
  44. ^ Rösel von Rosenhof, August Johann (1755). Der monatlich herausgegebenen Insecten-Belustigung [The monthly-published Insect Amusement] (in German). Vol. 3. Nürnberg: J.J. Fleischmann. p. 621. Archived from the original on 13 July 2015.
  45. ^ Jeon, Kwang W. (1973). Biology of Amoeba. New York: Academic Press. pp. 2–3. ISBN 9780123848505.
  46. ^ McAlpine, Daniel (1881). Biological atlas: a guide to the practical study of plants and animals. Edinburgh and London: W. & A. K. Johnston. pp. 17.
  47. ^ Bory de Saint-Vincent, J. B. G. M. "Essai d'une classification des animaux microscopiques." Agasse, Paris (1826).p. 28
  48. ^ McGrath, Kimberley; Blachford, Stacey, eds. (2001). Gale Encyclopedia of Science Vol. 1: Aardvark-Catalyst (2nd ed.). Gale Group. ISBN 978-0-7876-4370-6. OCLC 46337140.
  49. ^ Ehrenberg, Christian Gottfried. Organisation, systematik und geographisches verhältniss der infusionsthierchen: Zwei vorträge, in der Akademie der wissenschaften zu Berlin gehalten in den jahren 1828 und 1830. Druckerei der Königlichen akademie der wissenschaften, 1832. p. 59
  50. ^ Dujardin, Félix (1841). Histoire naturelle des zoophytes. Infusoires, comprenant la physiologie et la classificatin de ces animaux, et la manière de les étudier à l'aide du microscope [Natural history of zoophytes. Infusoria, understanding the physiology and classification of these animals, and how to study them using the microscope] (in French). Paris: Librarie Encyclopedique de Roret. doi:10.5962/bhl.title.10127.
  51. ^ Schmarda, Ludwig Karl (1871). Zoologie [Zoology] (in German). Wien [Vienna]: W. Braumüller.
  52. ^ Bütschli, Otto (1880). Protozoa. Abteilung 1. Sarkodina und Sporozoa. Dr. H.G. Bronn’s Klassen und Ordnungen des Thier-Reichs, wissenschaftlich dargestellt in Wort und Bild (in German). Vol. 1. Leipzig und Heidelberg: C. F. Winter'sche Verlagshandlung. doi:10.5962/bhl.title.11642.
  53. ^ a b c d e Page FC (1987). "The classification of 'naked' amoebae (phylum Rhizopoda)". Archiv für Protistenkunde. 133: 199–217. doi:10.1016/S0003-9365(87)80053-2.
  54. ^ Calkins, Gary N. (1909). Protozoölogy. New York: Lea & Febiger. pp. 38–40.
  55. ^ a b c Levine ND, Corliss JO, Cox FEG, Deroux G, Grain J, Honigberg BM, Leedale GF, Loeblich AR, Lom J, Lynn D, et al. (1980). "A newly revised classification of the Protozoa". Journal of Protozoology. 27 (1): 37–58. doi:10.1111/j.1550-7408.1980.tb04228.x. PMID 6989987.
  56. ^ Ptáčková, Eliška; Kostygov, Alexei Yu; Chistyakova, Lyudmila V; Falteisek, Lukáš; Frolov, Alexander O; Patterson, David J; Walker, Giselle; Cepicka, Ivan (2013). "Evolution of Archamoebae: Morphological and Molecular Evidence for Pelobionts Including Rhizomastix, Entamoeba, Iodamoeba, and Endolimax". Protist. 164 (3): 380–410. doi:10.1016/j.protis.2012.11.005. PMID 23312407.
  57. ^ a b Cavalier-Smith, Thomas (1996–1997). "Amoeboflagellates and Mitochondrial Cristae in Eukaryote Evolution: Megasystematics of the New Protozoan Subkingdoms Eozoa and Neozoa". Archiv für Protistenkunde. 147 (3–4): 237–258. doi:10.1016/S0003-9365(97)80051-6.
  58. ^ a b Cavalier-Smith, Thomas (1998). "A revised six-kingdom system of life". Biological Reviews. 73 (3): 203–266. doi:10.1111/j.1469-185X.1998.tb00030.x.
  59. ^ Adl, Sina M.; et al. (2012). "The Revised Classification of Eukaryotes". Journal of Eukaryotic Microbiology. 59 (5): 429–93. doi:10.1111/j.1550-7408.2012.00644.x. PMC 3483872. PMID 23020233.
  60. ^ a b Pawlowski, Jan; Burki, Fabien (2009). "Untangling the Phylogeny of Amoeboid Protists". The Journal of Eukaryotic Microbiology. 56 (1): 16–25. doi:10.1111/j.1550-7408.2008.00379.x. PMID 19335771.
  61. ^ Hibberd, David J.; Chretiennot-Dinet, Marie-Josèphe (11 May 2009). "The ultrastructure and taxonomy of Rhizochromulina marina gen. et sp.nov., an amoeboid marine chrysophyte". Journal of the Marine Biological Association of the United Kingdom. 59 (1): 179–193. doi:10.1017/S0025315400046269.
  62. ^ Horn, Susanne; Ehlers, Katrin; Fritzsch, Guido; Gil-Rodríguez, María Candelaria; Wilhelm, Christian; Schnetter, Reinhard (13 June 2007). "Synchroma grande spec. nov. (Synchromophyceae class. nov., Heterokontophyta): an amoeboid marine alga with unique plastid complexes". Protist. 158 (3): 277–293. doi:10.1016/j.protis.2007.02.004. PMID 17567535.
  63. ^ Gabaldón, Toni; Völcker, Eckhard; Torruella, Guifré (2022). "On the Biology, Diversity and Evolution of Nucleariid Amoebae (Amorphea, Obazoa, Opisthokonta)". Protist. 173 (4): 125895. doi:10.1016/j.protis.2022.125895. hdl:2117/369912. PMID 35841659.
  64. ^ Burki, Fabien; Kaplan, Maia; Tikhonenkov, Denis V.; Zlatogursky, Vasily; Minh, Bui Quang; Radaykina, Liudmila V.; Smirnov, Alexey; Mylnikov, Alexander P.; Keeling, Patrick J. (2016). "Untangling the early diversification of eukaryotes: a phylogenomic study of the evolutionary origins of Centrohelida, Haptophyta and Cryptista". Proceedings of the Royal Society B: Biological Sciences. 283: 20152802. doi:10.1098/rspb.2015.2802. PMC 4795036. PMID 26817772.
  65. ^ Yabuki, Akinori; Ishida, Ken-Ichiro; Cavalier-Smith, Thomas (7 June 2012). "Rigifila ramosa n. gen., n. sp., a Filose Apusozoan with a Distinctive Pellicle, is Related to Micronuclearia". Protist. 164 (1): 75–88. doi:10.1016/j.protis.2012.04.005. PMID 22682062.
  66. ^ a b Brown, Matthew W.; Heiss, Aaron A.; Kamikawa, Ryoma; Inagaki, Yuji; Yabuki, Akinori; Tice, Alexander K.; Shiratori, Takashi; Ishida, Ken-Ichiro; Hashimoto, Tetsuo; Simpson, Alastair G.B.; Roger, Andrew J. (2018). "Phylogenomics Places Orphan Protistan Lineages in a Novel Eukaryotic Super-Group". Genome Biology and Evolution. 10 (2): 427–433. doi:10.1093/gbe/evy014. PMC 5793813. PMID 29360967.
  67. ^ Brown, Matthew W.; Sharpe, Susan C.; Silberman, Jeffrey D.; Heiss, Aaron A.; Lang, B. Franz; Simpson, Alastair G. B.; Roger, Andrew J. (2013). "Phylogenomics demonstrates that breviate flagellates are related to opisthokonts and apusomonads". Proceedings of the Royal Society B: Biological Sciences. 280 (1769): 20131755. doi:10.1098/rspb.2013.1755. PMC 3768317. PMID 23986111.
  68. ^ Friedl, Peter; Borgmann, Stefan; Eva-B, Bröcker (2001). "Amoeboid leukocyte crawling through extracellular matrix: lessons from the Dictyostelium paradigm of cell movement". Journal of Leukocyte Biology. 70 (4): 491–509. doi:10.1189/jlb.70.4.491. PMID 11590185. S2CID 28731650.
  69. ^ Adamska, Maja (August 2016). "Sponges as models to study emergence of complex animals". Current Opinion in Genetics & Development. 39: 21–28. doi:10.1016/j.gde.2016.05.026.
  70. ^ Nakagaki; et al. (2000). "Intelligence: Maze-solving by an amoeboid organism". Nature. 407 (6803): 470. Bibcode:2000Natur.407..470N. doi:10.1038/35035159. PMID 11028990. S2CID 205009141.
  71. ^ Wehr, John D. (2003). Freshwater Algae of North America. San Diego and London: Academic Press. pp. 353. ISBN 978-0-12-741550-5.
  72. ^ "Algae World: diatom sex and life cycles". Algae World. Royal Botanic Garden Edinburgh. Archived from the original on 23 September 2014. Retrieved 1 March 2015.
  73. ^ Valle, L.G. (2014). "New species of Paramoebidium (trichomycetes, Mesomycetozoea) from the Mediterranean, with comments about the amoeboid cells in Amoebidiales". Mycologia. 106 (3): 481–90. doi:10.3852/13-153. PMID 24895422. S2CID 3383757.
  74. ^ Taylor, J. W. & Berbee, M. L. (2014). Fungi from PCR to Genomics: The Spreading Revolution in Evolutionary Biology. In: Systematics and Evolution. Springer Berlin Heidelberg. p. 52, [1] Archived 30 June 2015 at the Wayback Machine
  75. ^ Corliss, J. O. (1987). "Protistan phylogeny and eukaryogenesis". International Review of Cytology. 100: 319–370. doi:10.1016/S0074-7696(08)61703-9. ISBN 9780080586373. PMID 3549607.

Further reading

Wikisource has the text of the 1905 New International Encyclopedia article "Rhizopoda".
Wikimedia Commons has media related to Amoeba.

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