Davis-Gaither played at Appalachian State from 2015 to 2019.[1][2] As a senior in 2019, he was the Sun Belt Conference Defensive Player of the Year after recording 101 tackles, five sacks and an interception.[3][4] For his career, Davis-Gaither had 201 tackles, 6.5 sacks and the interception.[5]
Davis-Gaither was selected by the Cincinnati Bengals in the fourth round with the 107th pick of the 2020 NFL draft.[8]
In Week 17 against the Baltimore Ravens, Davis-Gaither recorded his first career interception off a pass thrown by Lamar Jackson during the 38–3 loss.[9]
On November 9, 2021, Davis-Gaither was placed on injured reserve after suffering a foot injury in Week 9.[10] In 2022, Davis recorded a career high 46 tackles and his first fumble recovery. He also intercepted a pass in the Bengals wildcard playoff win against the Ravens.
On March 13, 2024, Davis-Gaither signed a one-year contract extension with the Bengals.[11]