The 1935 All-Big Six Conference football team consists of American football players chosen by various organizations for All-Big Six Conference teams for the 1935 college football season. The selectors for the 1935 season included the Associated Press (AP).

• Lloyd Cardwell, Nebraska (AP-1)
• Jerry LaNoue, Nebraska (AP-1)
• Sam Francis, Nebraska (AP-1)
• Leo Ayers, Kansas State (AP-1)
• Henry Bauer, Nebraska (AP-2)
• Bill Breeden, Oklahoma (AP-2)
• George Hapgood, Kansas (AP-2)
• John Peterson, Kansas (AP-2)

• Rutherford Hayes, Kansas (AP-1)
• Bernie Scherer, Nebraska (AP-1)
• Ralph Churchill, Kansas State (AP-2)
• Les McDonald, Nebraska (AP-2)

• Fred Shirey, Nebraska (AP-1)
• J. W. "Dub" Wheeler, Oklahoma (AP-1)
• Don Flenthrope, Kansas State (AP-2)
• Harold Schafroth, Iowa State (AP-2)

• Dick Sklar, Kansas (AP-1)
• Ike Hayes, Iowa State (AP-1)
• Tom McCall, Kansas (AP-2)
• John Williams, Nebraska (AP-2)

• Edwin Phelps, Kansas (AP-1)
• Houston Betty, Missouri (AP-2)

AP = Associated Press^{[1] [2]}

• 1935 College Football All-America Team