The 1928 All-Big Six Conference football team consists of American football players chosen by various organizations for All-Big Six Conference teams for the 1928 college football season. The selectors for the 1928 season included the Associated Press (AP).

• Tom Churchill, Oklahoma (AP-1)
• Miller Brown, Missouri (AP-1)
• Harold Hauser, Kansas (AP-2)
• Cliff Ashburn, Nebraska (AP-2)

• Babe Lyon, Kansas State (AP-1)
• Marion Broadstone, Nebraska (AP-1)
• Ray Richards, Nebraska (AP-2)
• Glen B. Munn, Nebraska (AP-2)

• Elmer Holm, Nebraska (AP-1)
• Danny McMullen, Nebraska (AP-1)
• John Shannon, Kansas (AP-2)
• Carl Kern, Iowa State (AP-2)

• Ted James, Nebraska (AP-1)
• Bert Pearson, Kansas State (AP-2)

• Fay Russell, Nebraska (AP-1)
• Harry Lindblom, Iowa State (AP-2)

• Clair Sloan, Nebraska (AP-1)
• Robert Mehrle, Missouri (AP-1)
• A. Lynwood Haskins, Oklahoma (AP-2)
• Paul Trauger, Iowa State (AP-2)

• Blue Howell, Nebraska (AP-1)
• John Waldorf, Missouri (AP-2)

AP = Associated Press^[1]

• 1928 College Football All-America Team