SL-75102

SL-75102
Names
IUPAC name
4-[[(4-Chlorophenyl)-(3-fluoro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]butanoic acid
Other names
Progabide acid; LS-187121; SL-75-102-00
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
UNII
  • InChI=1S/C17H15ClFNO3/c18-12-5-3-11(4-6-12)17(20-9-1-2-16(22)23)14-10-13(19)7-8-15(14)21/h3-8,10,21H,1-2,9H2,(H,22,23)/b20-17+
    Key: RRAXPPHKWFOGGL-LVZFUZTISA-N
  • c1cc(ccc1/C(=N\CCCC(=O)O)/c2cc(ccc2O)F)Cl
Properties
C17H15ClFNO3
Molar mass 335.76 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

SL-75102, or progabide acid, is an active metabolite of progabide and an anticonvulsant GABA receptor agonist.[1][2]

References

  1. ^ Hamberger, C.; Barre, J.; Brandebourger, M.; Urien, S.; Taiclet, A.; Thenot, J. P.; Tillement, J. P. (April 1987). "Progabide and SL 75102 binding to plasma proteins and red blood cells in humans". Int J Clin Pharmacol Ther Toxicol. 25 (4): 178–84. PMID 3583466.
  2. ^ Kubová, H.; Haugvicová, R.; Mares, P. (1997). "Anticonvulsant effect of SL 75 102 in adult and immature rats". Physiol Res. 46 (1): 73–6. PMID 9728525.


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