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4-Fluoro-alpha-PHP
Legal status
Legal status	US: Unscheduled, illegal in Virginia;
Identifiers
	IUPAC name 1-(4-fluorophenyl)-2-(pyrrolidin-1-yl)hexan-1-one;
CAS Number	2230706-09-7;
PubChem CID	132989300;
CompTox Dashboard (EPA)	DTXSID201341964 ;
Chemical and physical data
Formula	C16H22FNO
Molar mass	263.356 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCC(C(=O)C1=CC=C(C=C1)F)N2CCCC2;
	InChI InChI=1S/C16H22FNO/c1-2-3-6-15(18-11-4-5-12-18)16(19)13-7-9-14(17)10-8-13/h7-10,15H,2-6,11-12H2,1H3; Key:BCJXLSGKMNRRKO-UHFFFAOYSA-N;

4-Fluoro-alpha-PHP (4F-PHP) is a recreational designer drug from the substituted cathinone family with stimulant effects, which first appeared on the illicit market in around 2017.^[2]^[3]^[4]

References

^ "§ 54.1-3446. Schedule I." Virginia Law. Retrieved 15 September 2023.
^ Liu C, Jia W, Li T, Hua Z, Qian Z (August 2017). "Identification and analytical characterization of nine synthetic cathinone derivatives N-ethylhexedrone, 4-Cl-pentedrone, 4-Cl-α-EAPP, propylone, N-ethylnorpentylone, 6-MeO-bk-MDMA, α-PiHP, 4-Cl-α-PHP, and 4-F-α-PHP". Drug Testing and Analysis. 9 (8): 1162–1171. doi:10.1002/dta.2136. PMID 27863142.
^ Apirakkan O, Frinculescu A, Shine T, Parkin MC, Cilibrizzi A, Frascione N, Abbate V (February 2018). "Analytical characterization of three cathinone derivatives, 4-MPD, 4F-PHP and bk-EPDP, purchased as bulk powder from online vendors". Drug Testing and Analysis. 10 (2): 372–378. doi:10.1002/dta.2218. PMID 28544816. S2CID 3542312.
^ Eshleman AJ, Nagarajan S, Wolfrum KM, Reed JF, Swanson TL, Nilsen A, Janowsky A (March 2019). "Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters". Psychopharmacology. 236 (3): 939–952. doi:10.1007/s00213-018-5059-5. PMC 6500773. PMID 30397775.