^ 4.04.1Stevens J, Gomez-Lobo V, Pine-Twaddell E. Insurance Coverage of Puberty Blocker Therapies for Transgender Youth. Pediatrics. December 2015, 136 (6): 1029–31. PMID 26527547. doi:10.1542/peds.2015-2849.
^ 5.05.1Alegría CA. Gender nonconforming and transgender children/youth: Family, community, and implications for practice. Journal of the American Association of Nurse Practitioners. October 2016, 28 (10): 521–527. PMID 27031444. S2CID 22374099. doi:10.1002/2327-6924.12363.
^Spack, N. P.; Edwards-Leeper, L.; Feldman, H. A.; Leibowitz, S.; Mandel, F.; Diamond, D. A.; Vance, S. R. (2012). Children and Adolescents With Gender Identity Disorder Referred to a Pediatric Medical Center. PEDIATRICS, 129(3), 418–425. doi:10.1542/peds.2011-0907
^Murchison G, Adkins D, Conard LA, Elliott T, Hawkins LA, Newby H, et al. Supporting and Caring for Transgender Children(PDF) (报告). American Academy of Pediatrics: 11. September 2016 [2022-11-14]. (原始内容存档(PDF)于2022-12-18). To prevent the consequences of going through a puberty that doesn't match a transgender child's identity, healthcare providers may use fully reversible medications that put puberty on hold.
^Mahfouda S, Moore JK, Siafarikas A, Zepf FD, Lin A. Puberty suppression in transgender children and adolescents. The Lancet Diabetes & Endocrinology. October 2017, 5 (10): 816–826. PMID 28546095. doi:10.1016/s2213-8587(17)30099-2. The few studies that have examined the psychological effects of suppressing puberty, as the first stage before possible future commencement of CSH therapy, have shown benefits.
^ 37.037.1Rafferty J. Ensuring Comprehensive Care and Support for Transgender and Gender-Diverse Children and Adolescents. Pediatrics. October 2018, 142 (4): e20182162. PMID 30224363. doi:10.1542/peds.2018-2162. Often, pubertal suppression...reduces the need for later surgery because physical changes that are otherwise irreversible (protrusion of the Adam's apple, male pattern baldness, voice change, breast growth, etc) are prevented. The available data reveal that pubertal suppression in children who identify as TGD generally leads to improved psychological functioning in adolescence and young adulthood.
^ 38.038.1Hembree WC, Cohen-Kettenis PT, Gooren L, Hannema SE, Meyer WJ, Murad MH, et al. Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology and Metabolism. November 2017, 102 (11): 3869–3903. PMID 28945902. doi:10.1210/jc.2017-01658. Treating GD/gender-incongruent adolescents entering puberty with GnRH analogs has been shown to improve psychological functioning in several domains", "In the future, we need more rigorous evaluations of the effectiveness and safety of endocrine and surgical protocols. Specifically, endocrine treatment protocols for GD/gender incongruence should include the careful assessment of the following: (1) the effects of prolonged delay of puberty in adolescents on bone health, gonadal function, and the brain (including effects on cognitive, emotional, social, and sexual development)". "the effects of prolonged delay of puberty in adolescents on bone health, gonadal function, and the brain (including effects on cognitive, emotional, social, and sexual development).
^Finnish guidelines for treatment of child and adolescent gender dysphoria(PDF). Council for Choices in Health Care (COHERE). March 2021 [22 April 2021]. (原始内容存档(PDF)于3 December 2020). Terveydenhuoltolain mukaan (8§) terveydenhuollon toiminnan on perustuttava näyttöön ja hyviin hoito- ja toimintakäytäntöihin. Alaikäisten osalta tutkimusnäyttöön perustuvia terveydenhuollon menetelmiä ei ole.
^Puberty Blockers. www.stlouischildrens.org. [18 August 2022]. (原始内容存档于2022-11-16) (英语).
^Bangalore Krishna, Kanthi; Fuqua, John S.; Rogol, Alan D.; Klein, Karen O.; Popovic, Jadranka; Houk, Christopher P.; Charmandari, Evangelia; Lee, Peter A.; Freire, A. V.; Ropelato, M. G.; Yazid Jalaludin, M. Use of Gonadotropin-Releasing Hormone Analogs in Children: Update by an International Consortium. Hormone Research in Paediatrics. 2019, 91 (6): 357–372. ISSN 1663-2826. PMID 31319416. doi:10.1159/000501336. GnRHa therapy prevents maturation of primary oocytes and spermatogonia and may preclude gamete maturation, and currently there are no proven methods to preserve fertility in early pubertal transgender adolescents.
^Rosenthal SM. Transgender youth: current concepts. Annals of Pediatric Endocrinology & Metabolism. December 2016, 21 (4): 185–192. PMC 5290172. PMID 28164070. doi:10.6065/apem.2016.21.4.185. The primary risks of pubertal suppression in gender dysphoric youth treated with GnRH agonists include adverse effects on bone mineralization, compromised fertility, and unknown effects on brain development.
^ 52.052.1As children line up at gender clinics, families confront many unknowns. Reuters. 6 October 2022 [10 October 2022]. (原始内容存档于2022-12-19) (英语). pubertal suppression may prevent key aspects of development during a sensitive period of brain organization", "we need high-quality research to understand the impacts of this treatment – impacts which may be positive in some ways and potentially negative in others.
^ 72.072.172.2The Lancet Child & Adolescent Health. A flawed agenda for trans youth. The Lancet Child & Adolescent Health. 14 May 2021, 5 (6): 385. ISSN 2352-4642. PMID 34000232. doi:10.1016/S2352-4642(21)00139-5. This stance wilfully ignores decades of use of and research about puberty blockers and hormone therapy
^Butler G, Wren B, Carmichael P. Puberty blocking in gender dysphoria: suitable for all?. Archives of Disease in Childhood. June 2019, 104 (6): 509–510. PMID 30655266. S2CID 58539498. doi:10.1136/archdischild-2018-315984. Our multidisciplinary staged approach is paced to ensure time for exploration of a range of possibilities and to ensure meaningful consent to any treatments.
^Ashley F. Puberty Blockers Are Necessary, but They Don't Prevent Homelessness: Caring for Transgender Youth by Supporting Unsupportive Parents. American Journal of Bioethics. February 2019, 19 (2): 87–89. PMID 30784386. S2CID 73478358. doi:10.1080/15265161.2018.1557277.
^Davies, Skye; McIntyre, Stephen; Rypma, Craig. Detransition rates in a national UK Gender Identity Clinic(PDF). 3rd Biennial EPATH Conference: Inside Matters, On Law, Ethics and Religion: 118. April 2019 [2021-05-27]. (原始内容存档(PDF)于2021-05-21).
^ 96.096.1Women and Gaming; ICU nurse Dawn Bilbrough; Poulomi Basu; Puberty blockers. Woman's Hour. 30 June 2020 [1 November 2021]. (原始内容存档于2022-11-10). the effects of treatment with GnRH analogues are considered to be fully reversible, so treatment can usually be stopped at any time after a discussion between you, your child and your MDT (multi-disciplinary team)," "the effects of treatment with GnRH analogues are considered to be fully reversible, so treatment can usually be stopped at any time after a discussion between you, your child and your MDT (multi-disciplinary team),
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