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利右苯丙胺（INN：lisdexamfetamine），也叫赖氨酸安非他命，品牌名Vyvanse和Elvanse，是中樞神經系統（CNS）兴奋剂右苯丙胺的前体药物，为一种苯丙胺类（英语：substituted amphetamine）的苯乙胺衍生物，即右旋安非他命和赖氨酸形成的酰胺。[4][5][6]该药品被用于治疗青少年及成年人的注意缺陷多动障碍（ADHD）以及成人的中重度暴食症，其给药方式为口服给药，药效通常在两个小时之内启动而能维持长达14个小时。[7]根据英国NCIE的意见，利右苯丙胺可作为二线药物，用于治疗在予足量哌甲酯6周后，在减少ADHD症状和相关损害方面没有获得足够的益处的6-17岁ADHD患者。[8]
赖右苯丙胺的常见副作用包括食欲不振、焦虑、腹泻、失眠、易怒和恶心。[9]
Table 9.2 Dextroamphetamine formulations of stimulant medicationDexedrine [Peak:2–3 h] [Duration:5–6 h] ...Adderall [Peak:2–3 h] [Duration:5–7 h]Dexedrine spansules [Peak:7–8 h] [Duration:12 h] ...Adderall XR [Peak:7–8 h] [Duration:12 h]Vyvanse [Peak:3–4 h] [Duration:12 h]
Onset of efficacy was earliest for d-MPH-ER at 0.5 hours, followed by d, l-MPH-LA at 1 to 2 hours, MCD at 1.5 hours, d, l-MPH-OR at 1 to 2 hours, MAS-XR at 1.5 to 2 hours, MTS at 2 hours, and LDX at approximately 2 hours. ... MAS-XR, and LDX have a long duration of action at 12 hours postdose
