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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Trihodienska sintaza
Trihodienska sintaza
Identifikatori
EC broj	4.2.3.6
CAS broj	101915-76-8
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Trihodienska sintaza (EC 4.2.3.6, trihodienska sintetaza, seskviterpenska ciklaza, trans,trans-farnezil-difosfat seskviterpenoid-lijaza) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (ciklizacija, formira trihodien).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

(2E,6E)-farnezil difosfat

\rightleftharpoons

trihodien + difosfat

Reference

^ Hohn, T.M. & Vanmiddlesworth, F. (1986). „Purification and characterization of the sesquiterpene cyclase trichodiene synthetase from Fusarium sporotrichioides”. Arch. Biochem. Biophys. 251: 756—761. PMID 3800398.
^ Hohn, T.M. & Beremand, P.D. (1989). „Isolation and nucleotide sequence of a sesquiterpene cyclase gene from the trichothecene-producing fungus Fusarium sporotrichioides”. Gene. 79: 131—138. PMID 2777086.
^ Rynkiewicz, M.J., Cane, D.E. and Christianson, D.W. (2001). „Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade”. Proc. Natl. Acad. Sci. USA. 98: 13543—13548. PMID 11698643.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Trichodiene+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Hohn, T.M. & Vanmiddlesworth, F. (1986). „Purification and characterization of the sesquiterpene cyclase trichodiene synthetase from Fusarium sporotrichioides”. Arch. Biochem. Biophys. 251: 756—761. PMID 3800398.

[2] Hohn, T.M. & Beremand, P.D. (1989). „Isolation and nucleotide sequence of a sesquiterpene cyclase gene from the trichothecene-producing fungus Fusarium sporotrichioides”. Gene. 79: 131—138. PMID 2777086.

[3] Rynkiewicz, M.J., Cane, D.E. and Christianson, D.W. (2001). „Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade”. Proc. Natl. Acad. Sci. USA. 98: 13543—13548. PMID 11698643.

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