Nadoksolol

Nadoksolol
Nazivi
IUPAC naziv
N′,3-Dihidroksi-4-naftalen-1-iloksibutanimidamid
Identifikacija
3D model (Jmol)
ChemSpider
EC broj 252-825-2
MeSH C006154
UNII
  • C1=CC=C2C(=C1)C=CC=C2OCC(C/C(=N/O)/N)O
Svojstva
C14H16N2O3
Molarna masa 260,29 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Nadoksolol je antiaritmički agens (i.e., lek za lečenje nepravilnog rada srca),[3] hemijski srodan po strukturi sa lekovima koji blokiraju beta-adrenergičke receptore kao što je propranolol.[4]

It does not appear to be marketed anywhere in the world.

Reference

  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Warembourg, H; Ducloux, G (1976). „Clinical study of a new anti-arrhythmia agent: nadoxolol”. Lille Med. 21 (4): 386—8. PMID 957857. 
  4. ^ Kapoor, M; Anand, N; Koul, S; Chimni, SS; Manhas, KS; Raina, C; Parshad, R; Taneja, SC; Qazi, GN (2003). „Kinetic resolution of 1-chloro-3-(1-naphthyloxy)-2-propanol, an intermediate in the synthesis of beta-adrenergic receptor blockers”. Bioorganic Chemistry. 31 (3): 259—69. PMID 12818235. doi:10.1016/s0045-2068(03)00050-6.