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Kopal-8-ol difosfatna hidrataza
Kopal-8-ol difosfatna hidrataza
Identifikatori
EC broj	4.2.1.133
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

Kopal-8-ol difosfatna hidrataza (EC 4.2.1.133, CcCLS) je enzim sa sistematskim imenom geranilgeranil-difosfat hidrolijaza (formira (13E)-8alfa-hidroksilabda-13-en-15-il difosfat).^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

(13E)-8alfa-hidroksilabda-13-en-15-il difosfat

\rightleftharpoons

geranilgeranil difosfat + H₂O

Za dejstvo ovog enzima je neophodan jon Mg²⁺.

Reference

^ Falara, V., Pichersky, E. and Kanellis, A.K. (2010). „A copal-8-ol diphosphate synthase from the angiosperm Cistus creticus' subsp. creticus is a putative key enzyme for the formation of pharmacologically active, oxygen-containing labdane-type diterpenes”. Plant Physiol. 154: 301—310. PMID 20595348.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Copal-8-ol+diphosphate+hydratase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Falara, V., Pichersky, E. and Kanellis, A.K. (2010). „A copal-8-ol diphosphate synthase from the angiosperm Cistus creticus' subsp. creticus is a putative key enzyme for the formation of pharmacologically active, oxygen-containing labdane-type diterpenes”. Plant Physiol. 154: 301—310. PMID 20595348.

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