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PubMed	članci
NCBI	proteini

Geraniltranstransferaza
Geraniltranstransferaza
Identifikatori
EC broj	2.5.1.10
CAS broj	37277-79-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Geraniltranstransferaza (EC 2.5.1.10, farnezil-difosfatna sintaza, geranilna transferaza I, preniltransferaza, farnezil pirofosfatna sintetaza, farnezilpirofosfatna sintetaza) je enzim sa sistematskim imenom geranil-difosfat:izopentenil-difosfat geraniltranstransferaza.^[1]^[2]^[3]^[4]^[5] Ovaj enzim katalizuje sledeću hemijsku reakciju

geranil difosfat + izopentenil difosfat

\rightleftharpoons

difosfat + (2E,6E)-farnezil difosfat

Neke forme ovog enzima takođe koriste dimetilalil difosfat kao supstrat.

Reference

^ Lynen, F., Agranoff, B.W., Eggerer, H., Henning, V. and Möslein, E.M. (1959). „Zur Biosynthese der Terpene. VI. γ,γ-Dimethyl-allyl-pyrophosphat und Geranyl-pyrophosphat, biologische Vorstufen des Squalens”. Angew. Chem. 71: 657—663.
^ Ogura, K., Nishino, T. and Seto, S. (1968). „The purification of prenyltransferase and isopentenyl pyrophosphate isomerase of pumpkin fruit and their some properties”. J. Biochem. (Tokyo). 64: 197—203. PMID 4303505.
^ Reed, B.C. & Rilling, H. (1975). „Crystallization and partial characterization of prenyltransferase from avian liver”. Biochemistry. 14: 50—54. PMID 1109590.
^ Takahashi, I. & Ogura, K. (1981). „Farnesyl pyrophosphate synthetase from Bacillus subtilis”. J. Biochem. (Tokyo). 89: 1581—1587. PMID 6792191.
^ Takahashi, I. & Ogura, K. (1982). „Prenyltransferases of Bacillus subtilis: undecaprenyl pyrophosphate synthetase and geranylgeranyl pyrophosphate synthetase”. J. Biochem. (Tokyo). 92: 1527—1537. PMID 6818223.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

(2E,6E)-farnesyl+diphosphate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Lynen, F., Agranoff, B.W., Eggerer, H., Henning, V. and Möslein, E.M. (1959). „Zur Biosynthese der Terpene. VI. γ,γ-Dimethyl-allyl-pyrophosphat und Geranyl-pyrophosphat, biologische Vorstufen des Squalens”. Angew. Chem. 71: 657—663.

[2] Ogura, K., Nishino, T. and Seto, S. (1968). „The purification of prenyltransferase and isopentenyl pyrophosphate isomerase of pumpkin fruit and their some properties”. J. Biochem. (Tokyo). 64: 197—203. PMID 4303505.

[3] Reed, B.C. & Rilling, H. (1975). „Crystallization and partial characterization of prenyltransferase from avian liver”. Biochemistry. 14: 50—54. PMID 1109590.

[4] Takahashi, I. & Ogura, K. (1981). „Farnesyl pyrophosphate synthetase from Bacillus subtilis”. J. Biochem. (Tokyo). 89: 1581—1587. PMID 6792191.

[5] Takahashi, I. & Ogura, K. (1982). „Prenyltransferases of Bacillus subtilis: undecaprenyl pyrophosphate synthetase and geranylgeranyl pyrophosphate synthetase”. J. Biochem. (Tokyo). 92: 1527—1537. PMID 6818223.

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