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Dihidropteroat sintaza
Dihidropteroat sintaza
	Dihidropteroat sintaza homodimer, Bacillus anthracis
Identifikatori
EC broj	2.5.1.15
CAS broj	9055-61-2
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Dihidropteroat sintaza (EC 2.5.1.15, dihidropteroat pirofosforilaza, DHPS, 7,8-dihidropteroat sintaza, 7,8-dihidropteroat sintetaza, 7,8-dihidropteroinska kiselina sintetaza, dihidropteroat sintetaza, dihidropteroinska sintetaza, 2-amino-4-hidroksi-6-hidroksimetil-7,8-dihidropteridin-difosfat:4-aminobenzoat 2-amino-4-hidroksidihidropteridin-6-meteniltransferaza) je enzim sa sistematskim imenom (2-amino-4-hidroksi-7,8-dihidropteridin-6-il)metil-difosfat:4-aminobenzoat 2-amino-4-hidroksidihidropteridin-6-meteniltransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

(2-amino-4-hidroksi-7,8-dihidropteridin-6-il)metil difosfat + 4-aminobenzoat

\rightleftharpoons

difosfat + 7,8-dihidropteroat

Reference

^ Richey, D.P. & Brown, G.M. (1969). „The biosynthesis of folic acid. IX. Purification and properties of the enzymes required for the formation of dihydropteroic acid”. J. Biol. Chem. 244: 1582—1592. PMID 4304228.
^ Shiota, T., Baugh, C.M., Jackson, R. and Dillard, R. (1969). „The enzymatic synthesis of hydroxymethyldihydropteridine pyrophosphate and dihydrofolate”. Biochemistry. 8: 5022—5028. PMID 4312465.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Dihydropteroate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Richey, D.P. & Brown, G.M. (1969). „The biosynthesis of folic acid. IX. Purification and properties of the enzymes required for the formation of dihydropteroic acid”. J. Biol. Chem. 244: 1582—1592. PMID 4304228.

[2] Shiota, T., Baugh, C.M., Jackson, R. and Dillard, R. (1969). „The enzymatic synthesis of hydroxymethyldihydropteridine pyrophosphate and dihydrofolate”. Biochemistry. 8: 5022—5028. PMID 4312465.

[1]

[2]