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Gama-humulenska sintaza
Gama-humulenska sintaza
Identifikatori
EC broj	4.2.3.56
CAS broj	110639-19-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Gama-humulenska sintaza (EC 4.2.3.56, humulenska ciklaza) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (formira gama-humulen).^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

(2E,6E)-farnezil difosfat

\rightleftharpoons

gama-humulen + difosfat

Reference

^ Steele, C.L., Crock, J., Bohlmann, J. and Croteau, R. (1998). „Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase”. J. Biol. Chem. 273: 2078—2089. PMID 9442047.
^ Little, D.B. & Croteau, R.B. (2002). „Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase”. Arch. Biochem. Biophys. 402: 120—135. PMID 12051690.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Gamma-humulene+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Steele, C.L., Crock, J., Bohlmann, J. and Croteau, R. (1998). „Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase”. J. Biol. Chem. 273: 2078—2089. PMID 9442047.

[2] Little, D.B. & Croteau, R.B. (2002). „Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase”. Arch. Biochem. Biophys. 402: 120—135. PMID 12051690.

[1]

[2]