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Damarenediolna II sintaza
Damarenediolna II sintaza
Identifikatori
EC broj	4.2.1.125
CAS broj	189354-84-5
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IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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Damarenediolna II sintaza (EC 4.2.1.125, damarenediolna sintaza, 2,3-oksidoskvalen (20S)-dammarenediol ciklaza, DDS, (S)-skvalen-2,3-epoksid hidrolijaza (formira damarenediol-II)) je enzim sa sistematskim imenom (3S)-2,3-epoksi-2,3-dihidroskvalen hidrolijaza (formira dammarenediol-II).^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

damarenediol II

\rightleftharpoons

(3S)-2,3-epoksi-2,3-dihidroskvalen + H₂O

Ova reakcija se odvija u reverznom smeru.

Reference

^ Tansakul, P., Shibuya, M., Kushiro, T. and Ebizuka, Y. (2006). „Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng”. FEBS Lett. 580: 5143—5149. PMID 16962103.
^ Han, J.Y., Kwon, Y.S., Yang, D.C., Jung, Y.R. and Choi, Y.E. (2006). „Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng”. Plant Cell Physiol. 47: 1653—1662. PMID 17088293.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Dammarenediol+II+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Tansakul, P., Shibuya, M., Kushiro, T. and Ebizuka, Y. (2006). „Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng”. FEBS Lett. 580: 5143—5149. PMID 16962103.

[2] Han, J.Y., Kwon, Y.S., Yang, D.C., Jung, Y.R. and Choi, Y.E. (2006). „Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng”. Plant Cell Physiol. 47: 1653—1662. PMID 17088293.

[1]

[2]