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(3S,6E)-nerolidolna sintaza
(3S,6E)-nerolidolna sintaza
Identifikatori
EC broj	4.2.3.48
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

(3S,6E)-nerolidolna sintaza (EC 4.2.3.48, (E)-nerolidolna sintaza, nerolidolna sintaza, (3S)-(E)-nerolidol sintaza, FaNES1) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (formira (3S,6E)-nerolidol).^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

(2E,6E)-farnezil difosfat + H₂O

\rightleftharpoons

(3S,6E)-nerolidol + difosfat

Ovaj enzim katalizuje jedan od koraka u formiranju (3E)-4,8-dimetilnona-1,3,7-triena.

Reference

^ Aharoni, A., Giri, A.P., Verstappen, F.W., Bertea, C.M., Sevenier, R., Sun, Z., Jongsma, M.A., Schwab, W. and Bouwmeester, H.J. (2004). „Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species”. Plant Cell. 16: 3110—3131. PMID 15522848.
^ Bouwmeester, H.J., Verstappen, F.W., Posthumus, M.A. and Dicke, M. (1999). „Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis”. Plant Physiol. 121: 173—180. PMID 10482672.
^ Degenhardt, J. & Gershenzon, J. (2000). „Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis”. Planta. 210: 815—822. PMID 10805454.
^ Arimura, G., Garms, S., Maffei, M., Bossi, S., Schulze, B., Leitner, M., Mithofer, A. and Boland, W. (2008). „Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling”. Planta. 227: 453—464. PMID 17924138.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

(3S,6E)-nerolidol+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Aharoni, A., Giri, A.P., Verstappen, F.W., Bertea, C.M., Sevenier, R., Sun, Z., Jongsma, M.A., Schwab, W. and Bouwmeester, H.J. (2004). „Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species”. Plant Cell. 16: 3110—3131. PMID 15522848.

[2] Bouwmeester, H.J., Verstappen, F.W., Posthumus, M.A. and Dicke, M. (1999). „Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis”. Plant Physiol. 121: 173—180. PMID 10482672.

[3] Degenhardt, J. & Gershenzon, J. (2000). „Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis”. Planta. 210: 815—822. PMID 10805454.

[4] Arimura, G., Garms, S., Maffei, M., Bossi, S., Schulze, B., Leitner, M., Mithofer, A. and Boland, W. (2008). „Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling”. Planta. 227: 453—464. PMID 17924138.

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