Saint-Lô is a commune. It is in the Manche department in west France.

Saint-Lô is twinned with:

• Saint-Ghislain, Belgium, since 1961
• Aalen, Germany, since 1979
• Christchurch, UK, since 1985
• Kervénanec, Lorient, France, since 1988
• Roanoke, Virginia, US, since 1999

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