Sufentanil

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Sufentanil
Identificare
Număr CAS56030-54-7[1][2]  Modificați la Wikidata
PubChem41693[3]  Modificați la Wikidata
DrugBankDB00708  Modificați la Wikidata
ChemSpider38043[4]  Modificați la Wikidata
UNIIAFE2YW0IIZ[2]  Modificați la Wikidata
KEGGC08022[5]  Modificați la Wikidata
ChEMBLCHEMBL658[6]  Modificați la Wikidata
Cod ATCN01AH03[7]  Modificați la Wikidata
SMILES
CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CS3)COC[3]  Modificați la Wikidata
InChI
InChI=InChI=1S/C22H30N2O2S/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20/h4-10,17H,3,11-16,18H2,1-2H3[3]  Modificați la Wikidata
Date chimice
FormulăC₂₂H₃₀N₂O₂S[3]  Modificați la Wikidata
Masă molară386,202799 u.a.m.[8]  Modificați la Wikidata
Modifică date / text Consultați documentația formatului

Sufentanilul este un analgezic opioid cu potență ridicată (de până la 1000 ori față de morfină). Este un agonist-I¼ specific, cu o afinitate pentru receptorii I¼ de 7 până la 10 ori mai mare comparativ cu fentanilul. Sufentanil are un efect analgezic de 10 ori mai mare decât remifentanil și de 5-10 ori mai mare decât fentanil. În prezența sa se menține stabilitatea hemodinamică și conferă un bun aport de oxigen la nivelul miocardului. Efectele maxime sunt atinse în câteva minute de la administrarea intravenoasă. De asemenea, sufentanilul poate fi utilizat și ca anestezic unic sau în combinație cu un anestezic local (utilizat epidural).(SPC - Sufentanil)

Note

  1. ^ a b CAS Common Chemistry, accesat în  
  2. ^ a b c d sufentanil (în engleză), Global Substance Registration System, accesat în  
  3. ^ a b c d e f g h i j k l „Sufentanil”, SUFENTANIL (în engleză), PubChem, accesat în  
  4. ^ a b Sufentanil (în engleză), ChemSpider, accesat în  
  5. ^ a b sufentanil (în engleză), ChEBI, accesat în  
  6. ^ a b SUFENTANIL (în engleză), ChEMBL, accesat în  
  7. ^ a b Sufentanil (în engleză), DrugBank,  
  8. ^ a b „Sufentanil”, SUFENTANIL (în engleză), PubChem, accesat în  


v • d • m
Analgezice (ATC N02A și ATC N02B)
Opioide
Alcaloizi din opiu
Compuși semi-sintetici
Compuși sintetici
Antiinflamatoare
nesteroidiene
Acetați
Coxibi
Celecoxib  • Etoricoxib  • Lumiracoxib‡  • Parecoxib  • Rofecoxib‡  • Valdecoxib‡
Fenamați
Oxicami
Pirazolone
Aminofenazonă  • Fenazonă  • Metamizol (noraminofenazonă)  • Propifenazonă
Propionați
Salicilați
Grupa paracetamolului
Acetanilid㇠ • Bucetin㇠ • Butacetin㇠ • Paracetamol (acetaminofen)#  • Parapropamol‡  • Fenacetin㇠ • Propacetamol‡
Canabinoide
Cannabidiol  • Cannabis  • Nabilonă  • Tetrahidrocannabinol (dronabinol)
Modulatori
ionici
Miorelaxante
Altele
Camfor  • Capsaicină  • Ketamină  • Mentol
v • d • m
Anestezice generale (ATC N01A)
Inhalatorii
Cloroetan‡  • Cloroform‡  • Ciclopropan‡  • Desfluran  • Eter dietilic‡  • Enfluran  • Etilen㇠ • Fluroxen ‡  • Halotan#  • Izofluran#  • Metoxifluran  • Metoxipropan‡  • Protoxid de azot#  • Sevofluran  • Tricloroetilen㇠ • Xenon
Injectabile
Barbiturice
Opioide
Alfentanil  • Anileridin㇠ • Fentanil#  • Morfină#  • Oxicodonă  • Remifentanil  • Sufentanil
Altele
Diazepam  • Esketamină  • Etomidat  • Fenciclidin㇠ • Fospropofol  • Ketamină#  • Propofol#

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