Oxicodonă

Oxicodonă
Identificare
Număr CAS76-42-6[1][2]  Modificați la Wikidata
PubChem5284603[3]  Modificați la Wikidata
DrugBankDB00497  Modificați la Wikidata
ChemSpider4447649[4]  Modificați la Wikidata
UNIICD35PMG570[1]  Modificați la Wikidata
KEGGC08018[5]  Modificați la Wikidata
ChEMBLCHEMBL656[6]  Modificați la Wikidata
Cod ATCN02AA05[7]  Modificați la Wikidata
SMILES
CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O[3]  Modificați la Wikidata
InChI
InChI=InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1[3]  Modificați la Wikidata
Date chimice
FormulăC₁₈H₂₁NO₄[3]  Modificați la Wikidata
Masă molară315,147 u.a.m.[3]  Modificați la Wikidata
Modifică date / text Consultați documentația formatului

Oxicodona este un analgezic opioid semi-sintetic derivat de tebaină, fiind utilizat în tratamentul durerilor severe.[8][9][10] Calea de administrare disponibilă este orală, formele uzuale fiind cele cu eliberate prelungită.[9][8]

Oxicodona este un agonist al receptorilor opioizi μ.[11] Pe cale orală, are un efect de aproximativ 1,5 ori mai mare decât morfina, pentru o masă echivalentă de substanță.[12]

Substanța a fost dezvoltată în Germania în 1916.[13] Este disponibilă sub formă de medicament generic.[9]

Note

  1. ^ a b c d oxycodone (în engleză), Global Substance Registration System, accesat în  
  2. ^ a b CAS Common Chemistry, accesat în  
  3. ^ a b c d e f g h i j k l m n „Oxicodonă”, oxycodone (în engleză), PubChem, accesat în  
  4. ^ a b (-)-Oxycodone (în engleză), ChemSpider, accesat în  
  5. ^ a b oxycodone (în engleză), ChEBI, accesat în  
  6. ^ a b OXYCODONE (în engleză), ChEMBL, accesat în  
  7. ^ a b Oxycodone (în engleză), DrugBank,  
  8. ^ a b [httpshttps://www.anm.ro/_/_RCP/rcp_4757_29.06.12.pdf „Rezumatul caracteristicilor produsului - Clorhidrat de oxicodonă Accord comprimate cu eliberare prelungită”] (PDF), Agenția Națională a Medicamentului și a Dispozitivelor Medicale din România, accesat în  
  9. ^ a b c „Oxycodone”. The American Society of Health-System Pharmacists. Accesat în . 
  10. ^ „Oxycodone”, DrugBank - Canadian Institutes of Health Research, accesat în  
  11. ^ Nicholas J Talley; Brad Frankum; David Currow (). Essentials of Internal Medicine 3e. Elsevier Health Sciences. pp. 491–. ISBN 978-0-7295-8081-6. 
  12. ^ „Stanford School of Medicine, Palliative Care, Opioid Conversion / Equivalency Table”. . Arhivat din original la . Accesat în . 
  13. ^ Sneader, W. (). Drug discovery: a history. Hoboken, NJ: Wiley. p. 119. ISBN 978-0-471-89980-8. 

Vezi și

 Acest articol legat de un medicament este un ciot. Puteți ajuta Wikipedia prin completarea lui.


v • d • m
Analgezice (ATC N02A și ATC N02B)
Opioide
Alcaloizi din opiu
Compuși semi-sintetici
Compuși sintetici
Antiinflamatoare
nesteroidiene
Acetați
Coxibi
Celecoxib  • Etoricoxib  • Lumiracoxib‡  • Parecoxib  • Rofecoxib‡  • Valdecoxib‡
Fenamați
Oxicami
Pirazolone
Aminofenazonă  • Fenazonă  • Metamizol (noraminofenazonă)  • Propifenazonă
Propionați
Salicilați
Grupa paracetamolului
Acetanilid㇠ • Bucetin㇠ • Butacetin㇠ • Paracetamol (acetaminofen)#  • Parapropamol‡  • Fenacetin㇠ • Propacetamol‡
Canabinoide
Cannabidiol  • Cannabis  • Nabilonă  • Tetrahidrocannabinol (dronabinol)
Modulatori
ionici
Miorelaxante
Altele
Camfor  • Capsaicină  • Ketamină  • Mentol

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