4-Metoxibenzilamina

4-Metoxibenzilamina
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4-Metoxibenzilamina, p-metoxibenzilamina, para-metoxibenzilamina, 4-aminometil-anisol ou anisilamina é o composto orgânico com a fórmula C8H11NO, fórmula linear CH3OC6H4CH2NH2 e massa molecular 137,18. Apresenta ponto de ebulição de 236-237 °C, ponto de fusão -10°C e densidade 1,05 g/mL a 25 °C. É classificado com o número CAS 2393-23-9 número de registro Beilstein 508206, número EC 219-247-2, número MDL MFCD00008122, PubChem Substance ID 24896615, CBNumber CB8326324 e MOL File 2393-23-9.mol.[1][2]

Pode ser usada como intermediário em síntese orgânica envolvendo uma reação de substituição nucleofílica aromática com posterior desproteção, numa conversão em duas etapas de 2-cloro-7-amido-1,8-naftiridina a 2,7-diamino-1,8-naftiridina.[3]

Referências

  1. ↑ 4-Methoxybenzylamine - www.sigmaaldrich.com
  2. ↑ 4-Methoxybenzylamine - www.chemicalbook.com
  3. ↑ Taiho Park, Michael F. Mayer, Shoji Nakashima, Steven C. Zimmerman; Preparation of 2,7-Diamino-1,8-naphthyridine: A Useful Building Block for Supramolecular Chemistry Convenient Synthesis of 2,7-Diamino-1,8-naphthyridine[ligação inativa]; SYNLETT 2005, No. 9, pp 1435–143601.06.205; Advanced online publication: 29.04.2005 - DOI: 10.1055/s-2005-868507; Art ID: S02405ST

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