Limfosit

Limfosit
Sebuah imej mikroskop elektron imbasan untuk satu sel limfosit manusia
Butiran
SistemSistem imun
FungsiSel darah putih
Pengenalpastian
MeSHD008214
THH2.00.04.1.02002
FMA84065 FMA:62863, 84065
Istilah anatomi mikroanatomi

Limfosit ialah sejenis sel darah putih (leukosit) yang merupakan sebahagian daripada sistem imun dalam kebanyakan haiwan vertebrata.[1] Antara jenis-jenis sel limfosit yang ada termasuklah sel T (untuk keimunan penyesuaian sitotoksik dan berperantara sel), sel B (untuk keimunan penyesuaian pacuan antibodi dan humoral),[2][3] serta sel limfoid semula jadi (ILC) (sel "kelihatan seperti sel T semula jadi" ini terlibat dalam keimunan mukosa dan homeostasis). Antara subjenis ILC terpenting ialah terutamanya sel pemusnah semula jadi (yang berfungsi dalam pengantaraan sel, keimunan semula jadi sitotoksik). Kesemua jenis limfosit merupakan jenis sel utama yang terdapat dalam limfa, yang mendorong nama "limfosit" (dengan sit bermaksud sel).[4] Limfosit membentuk antara 18% sehingga mencecah 42% daripada sel darah putih yang beredar.[2]

Jenis

Limfosit berwarna yang dikelilingi oleh sel darah merah, dilihat menggunakan mikroskop cahaya
Pengimejan langsung 4D dinamik nukleus sel T dilihat menggunakan mikroskop holotomografi
Limfosit yang bercalit Giemsa dalam darah periferi

Tiga jenis utama limfosit ialah sel T, sel B dan sel pemusnah semula jadi (NK).[2] Limfosit boleh dikenal pasti melalui nukleusnya yang besar.

Rujukan

  1. ^ Janeway C, Travers P, Walport M, Shlomchik M (2001). Immunobiology (ed. 5th). New York and London: Garland Science. ISBN 0-8153-4101-6.
  2. ^ a b c Omman, Reeba A.; Kini, Ameet R. (2020). "Leukocyte development, kinetics, and functions". Dalam Keohane, Elaine M.; Otto, Catherine N.; Walenga, Jeanine N. (penyunting). Rodak's Hematology: Clinical Principles and Applications (ed. 6th). St. Louis, Missouri: Elsevier. m/s. 117–135. ISBN 978-0-323-53045-3.
  3. ^ Cohn, Lauren; Hawrylowicz, Catherine; Ray, Anuradha (2014). "Biology of Lymphocytes". Middleton's Allergy: Principles and Practice (ed. 8th). Philadelphia: Saunders. m/s. 203–214. doi:10.1016/B978-0-323-08593-9.00013-9. ISBN 9780323085939. Dicapai pada 22 July 2020.
  4. ^ "NCI Dictionary of Cancer Terms". National Cancer Institute. Dicapai pada 22 July 2020. A type of immune cell that is made in the bone marrow and is found in the blood and in lymph tissue. The two main types of lymphocytes are B lymphocytes and T lymphocytes. B lymphocytes make antibodies, and T lymphocytes help kill tumor cells and help control immune responses. A lymphocyte is a type of white blood cell.

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