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(a) SCF contains three core subunits—the RING protein Rbx1, the cullin Cul1, and Skp1. Rbx1 binds the E2–ubiquitin conjugate. The target protein binds to an F-box protein that is bound to the enzyme core via interactions with the Skp1 subunit. After binding of a target protein to the F-box protein, the ubiquitin is transferred from E2 and attached via a peptide bond to a lysine side chain in the target protein. (b) A composite model structure for human SCF derived from X-ray structures of...

American college football season 1984 Notre Dame Fighting Irish footballAloha Bowl, L 20–27 vs. SMUConferenceIndependentRecord7–5Head coachGerry Faust (4th season)Defensive coordinatorA. J. ChristoffCaptains Mike Golic Joe Johnson Larry Williams Home stadiumNotre Dame Stadium (c. 59,075, grass)Seasons← 19831985 → 1984 NCAA Division I-A independents football records vte Conf Overall Team W   L   T W   L   T No. 5 Boston College  ...

Halford MackinderHalford John MackinderLahir(1861-02-15)15 Februari 1861Gainsborough, InggrisMeninggal6 Maret 1947(1947-03-06) (umur 86)Kebangsaan United KingdomKarier ilmiahBidangGeography, Geopolitics, Geostrategy Halford John Mackinder (lahir pada tahun 1861) adalah seorang berkebangsaan Inggris yang mempunyai keahlian dalam bidang geografi, geopolitik, dan geostrategi.[1] Biografi Halford dilahirkan di Gainsborough, Lincolnshire, Inggris.[1] Ia adalah anak seora...

Canadian politician Michael KramMPKram in 2019Member of Parliamentfor Regina—WascanaIncumbentAssumed office October 21, 2019Preceded byRalph Goodale Personal detailsBorn (1978-12-20) December 20, 1978 (age 45)Regina, Saskatchewan, CanadaPolitical partyConservativeResidenceRegina, Saskatchewan[1]Education University of Regina (BA, BS) Michael Kram MP (born December 20, 1978) is a Canadian politician who was elected as a Conservative to represent the riding of Regina—Wascan...

Men's golf competition between the United States and Europe in September and October 2023 44th Ryder Cup MatchesDates29 September – 1 October 2023VenueMarco Simone Golf and Country ClubLocationGuidonia Montecelio, Metropolitan City of Rome Capital, ItalyCaptainsLuke Donald[a] (Europe)Zach Johnson (USA) 161⁄2 111⁄2 Europe wins the Ryder CupLocation mapMarco Simone G&CCLocation in ItalyShow map of ItalyMarco Simone G&CCLocation in LazioShow map of LazioMarco Simone...

Species of amphibian Phrynopus kauneorum Conservation status Endangered  (IUCN 3.1)[1] Scientific classification Domain: Eukaryota Kingdom: Animalia Phylum: Chordata Class: Amphibia Order: Anura Family: Strabomantidae Genus: Phrynopus Species: P. kauneorum Binomial name Phrynopus kauneorumLehr [de], Aguilar [fr], and Köhler, 2002[2] Phrynopus kauneorum is a species of frogs in the family Strabomantidae. It is endemic to the Andes of Peru an...

مسجد الفيحاء معلومات عامة الدولة الأردن  تعديل مصدري - تعديل   مسجد الفيحاء مسجد الفيحاء، أحد مساجد مدينة عمان الأردنية، ويقع في منطقة العبدلي. وهو مبني على هيئة مساجد سوريا التراثية القديمة. يقام فيه نشاطات متعددة مثل إحياء لذكرى المولد النبوي ونشاطات خيرية واجتماعي...

Expendable Rocket developed by USA during the Cold War to launch satellites Thor 320 Delta 9 rocket with UK first satellite Ariel 1, 26 April 1962FunctionExpendable launch systemCountry of originUnited StatesLaunch historyStatusRetiredLaunch sitesCape Canaveral, LC-17Total launches12Success(es)11Failure(s)1First flight13 May 1960Last flight18 September 1962[edit on Wikidata] The Thor-Delta, also known as Delta DM-19 or just Delta was an early American expendable launch system used for 12 ...

Senusret ISesostris ITượng của Senusret I tại Viện bảo tàng Altes, BerlinPharaonVương triều1971 TCN - 1926 TCN (Vương triều thứ 12)Tiên vươngAmenemhat IKế vịAmenemhat IITên hiệu Tên riêng Senusret Man of Wosret Tên Horus Ankh mesut Living of births Tên Nebty (hai quý bà) Ankh mesut Living of births Tên Horus Vàng Ankh mesut Living of births Hôn phốiNeferu IIIChaAmenemhat IMẹNeferitatenen[1]Chôn cấtKim tự tháp tại el-LishtLăng mộN...

Japanese high speed train type E3 seriesReliveried E3-1000 series set L53 on a Tsubasa service, June 2022In service22 March 1997; 27 years ago (1997-03-22) – presentManufacturerKawasaki Heavy Industries, Tokyu Car CorporationFamily nameMini-shinkansenReplaced400 seriesConstructed1995–2009Scrapped2013–Number built261 vehicles (41 sets)Number in service84 vehicles (12 sets) (as of March 2024[update])Number scrapped163 vehiclesSuccessorE6 series, E8 s...

Liga I 2017-2018 Competizione Liga I Sport Calcio Edizione 100ª Organizzatore LPF Date dal 14 luglio 2017al 2 giugno 2018 Luogo  Romania Partecipanti 14 Formula Stagione regolare (girone all'italiana con andata e ritorno); Poule Scudetto e Poule Retrocessione Risultati Vincitore  CFR Cluj(4º titolo) Secondo  FCSB Retrocessioni  SSU Politehnica Timișoara Daco-Getica Bucarest Statistiche Miglior marcatore George Țucudean Harlem Gnohéré(15 a testa) In...

Musa al-Kazim7º Imam sciita duodecimano e alawitaPredecessoreJa'far al-Sadiq SuccessoreʿAlī al-Riḍā Nascitaal-Abwāʾ, 6 novembre 745 MorteBaghdad, settembre 799 Abū Ibrāhīm Mūsā b. Jaʿfar b. Muhammad al-Kāẓim' Abū Ibrāhīm Mūsā b. Jaʿfar b. Muhammad al-Kāẓim' (Arabo ﻣﻮسى ﺑﻦ ﺟﻌﻔﺮ ﺍﻟﻜﺎﻇﻢ; al-Abwāʾ, 6 novembre 745 – Baghdad, settembre 799) è stato il settimo imam sciita duodecimano[1]. Moschea al-Kazimiyya Indice 1 Biografi...

American Mormon leader Charles H. HartHart, c. 1934 First Council of the SeventyApril 9, 1906 (1906-04-09) – September 29, 1934 (1934-09-29)Called byJoseph F. Smith Personal detailsBornCharles Henry Hart(1866-07-05)July 5, 1866Bloomington, Idaho Territory, United StatesDiedSeptember 29, 1934(1934-09-29) (aged 68)Salt Lake City, Utah, United States Biography portal   LDS movement portal Hart c. 1920 Charles Henry Hart (July 5, 18...

Партеніон 45°20′57″ пн. ш. 36°36′15″ сх. д. / 45.34934000002777310° пн. ш. 36.60433300002777202° сх. д. / 45.34934000002777310; 36.60433300002777202Координати: 45°20′57″ пн. ш. 36°36′15″ сх. д. / 45.34934000002777310° пн. ш. 36.60433300002777202° сх. д. / 45.34934000002777310; 36.60433300002777202Кр...

Breakfast cereal made by Post Honey Oh's!Post Honey Oh's – Sweetened Cereal with Honey, with milkProduct typeBreakfast cerealOwnerPost Consumer BrandsIntroduced1980; 44 years ago (1980)Previous ownersQuaker OatsWebsitepostconsumerbrands.com/ohs Honey Ohs! (previously Oh's!, Oh!s, or Honey Graham Oh!s) is a breakfast cereal made by Post Cereals, but originally introduced by the Quaker Oats Company. The original Oh's! cereal was introduced in 1980 by the Quaker Oats Co. It o...

Cet article est une ébauche concernant une localité slovaque. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Svinná Administration Pays Slovaquie Région Trenčín District Trenčín Statut Village Starosta (maire) Mandat Anna Sýkorová (Indépendant) mandat : 2018-2022 Code postal 913 24 Plaqueminéralogique TN Code LAU 2 506532 Démographie Population 1 559 hab. (31 déc. 2018) Densité 181...

Questa voce o sezione sull'argomento chimici tedeschi non cita le fonti necessarie o quelle presenti sono insufficienti. Puoi migliorare questa voce aggiungendo citazioni da fonti attendibili secondo le linee guida sull'uso delle fonti. Robert Wilhelm Eberhard Bunsen Robert Wilhelm Eberhard Bunsen (Gottinga, 31 marzo 1811 – Heidelberg, 16 agosto 1899) è stato un chimico e fisico tedesco. Indice 1 Biografia 2 Onorificenze 3 Note 4 Voci correlate 5 Altri progetti 6 Collegamenti esterni...

Pemilihan umum Presiden Argentina 20112007201523 Oktober 2011Pemilih terdaftar28.916.183Kehadiran pemilih79,39%Kandidat   Calon Cristina Fernández de Kirchner Hermes Binner Ricardo Alfonsín Partai Partido Justicialista Partai Sosialis Unión Cívica Radical Aliansi Front untuk Kemenangan Frente Amplio Progresista UDESO Negara bagian Buenos Aires Santa Fe Buenos Aires Wakil Amado Boudou Norma Morandini Javier González Fraga Negara bagian 22 + CABA 0 0 Suara rakyat 11.86...

この存命人物の記事には検証可能な出典が不足しています。 信頼できる情報源の提供に協力をお願いします。存命人物に関する出典の無い、もしくは不完全な情報に基づいた論争の材料、特に潜在的に中傷・誹謗・名誉毀損あるいは有害となるものはすぐに除去する必要があります。出典検索?: 池江泰郎 – ニュース · 書籍 · スカラー · CiNii ...

.bs البلد جزر البهاما  الموقع الموقع الرسمي  تعديل مصدري - تعديل   bs. هو نطاق إنترنت من صِنف مستوى النطاقات العُليا في ترميز الدول والمناطق، للمواقع التي تنتمي لجزر الباهماس.[1][2] انظر أيضًا .ba .rs مراجع ^ النطاق الأعلى في ترميز الدولة (بالإنجليزية). ORSN [الإنجليزية...