TNFRSF19

Abbozzo proteine
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Recettore del fattore di necrosi tumorale 19
Gene
HUGOTNFRSF19 TAJ; TAJ-alpha; TRADE; TROY
Entrez55504
LocusChr. 13 q12.12
Proteina
OMIM606122
UniProtQ9NS68
Modifica dati su Wikidata · Manuale

Il recettore del fattore di necrosi tumorale 19 è una proteina recettoriale che, nell'essere umano, è codificata dal gene TNFRSF19 e fa parte della superfamiglia dei recettori del fattore di necrosi tumorale[1].

Tale recettore è espresso soprattutto durante lo sviluppo embrionale, nel quale riveste un ruolo essenziale. Interagisce con i membri della famiglia TRAF e attiva il sistema di trasduzione del segnale mediato dalla proteina JNK, inducendo un meccanismo di morte cellulare programmata indipendente dalle caspasi. Ne sono state descritte diverse isoforme[1].

Note

  1. ^ a b Entrez Gene: TNFRSF19 tumor necrosis factor receptor superfamily, member 19, su ncbi.nlm.nih.gov.

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