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Quorum sensing

Zelula-dentsitatea baxua denean, autoinduktore-dentsitatea txikia izango da, txikiegia gene onuragarriaren adierazpena bultzatzeko. Zelula-dentsitatea emendatu ahala, antoinduktore-dentsitatea emendatuko da, ekoizpen proteikoari hasiera emanez.

Biologian, quorum sensinga, autoindukzioa edo quorum-pertzepzioa gene-erregulazioaren bidezko zelula-hazkuntza bateko zelula-populazioaren dentsitatea detektatzeko eta honi erantzuteko gaitasuna da.[1] Quorum sensingaren bidez autoinduktore deritzen seinale kimikoak askatzen dituzte, komunitate osoaren gene onuragarrien adierazpen genetikoa emendatzen edo induzitzen dutenak. Quorum sensing hau, bereziki maila zelularrean ematen bada (adibidez, minbizi-zelulen arteko komunikazioan)[2], zenbait intsektu-taldeek ere, inurrien kasu, halako mekanismoak erabiltzen dituzte;[3] adibidez, habia sortzeko momentuan.[4]

Erreferentziak

  1. ↑ (Ingelesez) Miller, Melissa B.; Bassler, Bonnie L.. (2001-10). «Quorum Sensing in Bacteria» Annual Review of Microbiology 55 (1): 165–199.  doi:10.1146/annurev.micro.55.1.165. ISSN 0066-4227. (kontsulta data: 2020-02-13).
  2. ↑ (Ingelesez) Ali, Isra; Alfarouk, Khalid O.; Reshkin, Stephan J.; Ibrahim, Muntaser E.. (2018-01-16). «Doxycycline as Potential Anti-cancer Agent» Anti-Cancer Agents in Medicinal Chemistry 17 (12)  doi:10.2174/1871520617666170213111951. (kontsulta data: 2020-02-13).
  3. ↑ (Ingelesez) Pontes, Mauricio H.; Babst, Markus; Lochhead, Robert; Oakeson, Kelly; Smith, Kari; Dale, Colin. (2008-10-28). Valdivia, Raphael H. ed. «Quorum Sensing Primes the Oxidative Stress Response in the Insect Endosymbiont, Sodalis glossinidius» PLoS ONE 3 (10): e3541.  doi:10.1371/journal.pone.0003541. ISSN 1932-6203. PMID 18958153. PMC PMC2568817. (kontsulta data: 2020-02-13).
  4. ↑ (Ingelesez) Franks, Nigel R.; Stuttard, Jonathan P.; Doran, Carolina; Esposito, Julian C.; Master, Maximillian C.; Sendova-Franks, Ana B.; Masuda, Naoki; Britton, Nicholas F.. (2015-12). «How ants use quorum sensing to estimate the average quality of a fluctuating resource» Scientific Reports 5 (1): 11890.  doi:10.1038/srep11890. ISSN 2045-2322. PMID 26153535. PMC PMC4495386. (kontsulta data: 2020-02-13).

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