Ze'ev Sherf (Hebrew: זאב שרף, 21 April 1904 – 18 April 1984) was an Israeli politician who held several ministerial portfolios in the 1960s and 1970s.
During World War II he was a member of the Haganah command, and following the war, worked for the Jewish Agency for Israel for two years.
In 1947 he was appointed secretary of the Situation Committee, which helped create the administrative apparatus of the new state. Following independence, he served as secretary of the government until 1957.