Following shakedown off Florida's Cape Kennedy, James Monroe spent the early months of 1964 in ballistic missile tests. She departed for her first deterrent patrol in June 1964. On 17 January 1967, James Monroe completed her twelfth deterrent patrol, having operated from both Holy Loch, Scotland, and Rota, Spain. Preparations for the arrival of the submarine squadron went forward with haste throughout the remainder of 1978 and into 1979. Commander Submarine Squadron 16 greeted the submarine tender USS Simon Lake, when she arrived at Kings Bay on 2 July 1979. Four days later, USS James Monroe entered Kings Bay and moored alongside Simon Lake's starboard side to begin a routine refit in preparation for another nuclear weapons deterrence patrol.
This article includes information collected from the Naval Vessel Register, which, as a U.S. government publication, is in the public domain. The entry can be found here.
Photo gallery of USS James Monroe at NavSource Naval History