Sulconazole

Sulconazole
Clinical data
Trade namesExelderm
AHFS/Drugs.comMonograph
MedlinePlusa698018
Routes of
administration		Topical
ATC code
Identifiers
  • 1-(2-{[(4-Chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H15Cl3N2S
Molar mass397.74 g·mol−1
3D model (JSmol)
  • Clc1ccc(c(Cl)c1)C(SCc2ccc(Cl)cc2)Cn3ccnc3
  • InChI=1S/C18H15Cl3N2S/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 checkY
  • Key:AFNXATANNDIXLG-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Sulconazole (trade name Exelderm) is an antifungal medication of the imidazole class. It is available as a cream or solution to treat skin infections such as athlete's foot, ringworm, jock itch, and tinea versicolor.[1][2] Although not used commercially for insect control, sulconazole nitrate exhibits a strong anti-feeding effect on the keratin-digesting Australian carpet beetle larvae Anthrenocerus australis.[3]

References

  1. ^ Drugs.com: sulconazole topical
  2. ^ Fromtling RA (April 1988). "Overview of medically important antifungal azole derivatives". Clinical Microbiology Reviews. 1 (2): 187–217. doi:10.1128/CMR.1.2.187. PMC 358042. PMID 3069196.
  3. ^ Sunderland MR, Cruickshank RH, Leighs SJ (2014). "The efficacy of antifungal azole and antiprotozoal compounds in protection of wool from keratin-digesting insect larvae". Textile Research Journal. 84 (9): 924–931. doi:10.1177/0040517513515312. S2CID 135799368.
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